[Treatment of patients with severe glucocorticoid-refractory ulcerative colitis: cyclosporine or infliximab?]
SourceNederlands Tijdschrift voor Geneeskunde, 157, 38, (2013), pp. A6130
Article / Letter to editor
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Nederlands Tijdschrift voor Geneeskunde
SubjectIGMD 2: Molecular gastro-enterology and hepatology
- Cyclosporine and infliximab are so-called 'rescue-therapies' as last resort for the treatment of patients with severe glucocorticoid-refractory ulcerative colitis.- A recent study found that cyclosporine and infliximab are similar in terms of efficacy in the treatment of patients with severe ulcerative colitis.- Cyclosporine may be prescribed as a bridge to treatment with thiopurines; infliximab may be prescribed when a patient is intolerant or refractory to thiopurines.- Preoperative treatment with cyclosporine or infliximab does not affect the number of postoperative complications.
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