Molecular imaging and carbonic anhydrase IX-targeted radioimmunotherapy in clear cell renal cell carcinoma
Publication year
2013Source
Immunotherapy, 5, 5, (2013), pp. 489-95ISSN
Publication type
Article / Letter to editor

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Organization
Nuclear Medicine
Urology
Journal title
Immunotherapy
Volume
vol. 5
Issue
iss. 5
Page start
p. 489
Page end
p. 95
Subject
ONCOL 3: Translational research; ONCOL 3: Translational research N4i 1: Pathogenesis and modulation of inflammation; ONCOL 3: Translational research NCMLS 2: Immune Regulation; ONCOL 3: Translational research NCMLS 3: Tissue engineering and pathology; ONCOL 5: Aetiology, screening and detectionAbstract
Conventional imaging is suboptimal at evaluating disease status in renal cell carcinoma (RCC) because of poor sensitivity. Furthermore, there is an unmet need for the treatment of metastatic RCC, both in terms of improvement of progression-free survival and limitation of toxicity. For this reason, radionuclide imaging and radionuclide therapy are extensively investigated. This review provides an overview of the current progress in molecular imaging and radionuclide therapy in clear cell RCC and will focus on promising detection and therapy strategies targeting the carbonic anhydrase IX antigen, which is expressed in clear cell RCC.
This item appears in the following Collection(s)
- Academic publications [227683]
- Faculty of Medical Sciences [86198]
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