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Title: Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.
Author(s): Steenwinkel, J.E. de; Kate, M.T. Ten; Knegt, G.J. de; Kremer, K. ; Aarnoutse, R.E. ; Boeree, M.J. ; Verbrugh, H.A.; Soolingen, D. van ; Bakker-Woudenberg, I.A.
Publication year: 2012
Source: Emerging Infectious Diseases, vol. 18, iss. 4, (2012), pp. 660-663
ISSN: 1080-6040
DOI: https://doi.org/10.3201/eid1804.110912
Annotation: 1 april 2012
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/110971   http://hdl.handle.net/2066/110971

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Subject: N4i 3: Poverty-related infectious diseases
N4i 3: Poverty-related infectious diseases NCEBP 13: Infectious diseases and international health
N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity
N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity
Organization: Clinical Pharmacy
Pulmonary Diseases
Medical Microbiology
Journal title:
Emerging Infectious Diseases
Volume: vol. 18
Issue: iss. 4
Page start: p. 660
Page end: p. 663
Abstract:
To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's association with multidrug-resistant tuberculosis.

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