Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.
SourceEmerging Infectious Diseases, 18, 4, (2012), pp. 660-663
1 april 2012
Article / Letter to editor
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Emerging Infectious Diseases
SubjectN4i 3: Poverty-related infectious diseases; N4i 3: Poverty-related infectious diseases NCEBP 13: Infectious diseases and international health; N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity; N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity
To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's association with multidrug-resistant tuberculosis.
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