Publication year
2012Source
Nederlands Tijdschrift voor Tandheelkunde, 119, 4, (2012), pp. 186-90ISSN
Annotation
01 april 2012
Publication type
Article / Letter to editor

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Organization
Dentistry
Journal title
Nederlands Tijdschrift voor Tandheelkunde
Volume
vol. 119
Issue
iss. 4
Page start
p. 186
Page end
p. 90
Subject
NCMLS 6: Genetics and epigenetic pathways of disease IGMD 3: Genomic disorders and inherited multi-system disordersAbstract
Bisphosphonates are used in the treatment of various diseases which are associated with a disturbance of the balance between bone apposition and degradation. The most important complication of bisphosphonate use is osteonecrosis of the jaw. Certain components of an orthodontic treatment plan, such as the extraction of 1 or more teeth, are important risk factors in developing this complication. In addition to the desired effects on the bone metabolism, bisphosphonates may delay tooth eruption and inhibit or block orthodontic tooth movement. Nevertheless, case studies suggest that orthodontic treatment is possible despite the use of bisphosphonates. However, it is recommended to avoid orthodontic treatment unless this is strictly indicated.
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- Faculty of Medical Sciences [89012]
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