[Endoscopic versus surgical treatment of infected necrotising pancreatitis: the TENSION study].

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Title:	[Endoscopic versus surgical treatment of infected necrotising pancreatitis: the TENSION study].
Author(s):	Brunschot, S. van; Santvoort, H.C. van ; Gooszen, H.G. ; Fockens, P.
Publication year:	2012
Source:	Nederlands Tijdschrift voor Geneeskunde, vol. 156, iss. 4, (2012), pp. A4329
ISSN:	0028-2162
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/110265
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Subject:	NCEBP 2: Evaluation of complex medical interventions
Organization:	Operating Rooms
Journal title:	Nederlands Tijdschrift voor Geneeskunde
Volume:	vol. 156
Issue:	iss. 4
Page start:	p. A4329
Page end:	p. A4329
Abstract:	In patients with infected necrotising pancreatitis there is a significant risk (40%) of complications and mortality with the surgical step-up approach. This approach consists of percutaneous retroperitoneal drainage, if necessary followed by video-assisted retroperitoneal debridement. An alternative treatment is an endoscopic step-up approach consisting of endoscopic transluminal drainage, if necessary followed by endoscopic transluminal necrosectomy. The Dutch Pancreatitis Study Group has recently started the nationwide randomized TENSION-trial, in which in 98 patients the endoscopic step-up approach is compared with the surgical method. The primary endpoint is a composite of mortality and major morbidity (new onset organ failure, bleeding, perforation of a hollow organ or incisional hernia for which intervention is needed).