[Better pain management in chronic pancreatitis through early surgery?].
SourceNederlands Tijdschrift voor Geneeskunde, 156, 5, (2012), pp. A4469
Article / Letter to editor
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Nederlands Tijdschrift voor Geneeskunde
SubjectIGMD 2: Molecular gastro-enterology and hepatology; IGMD 2: Molecular gastro-enterology and hepatology NCMLS 5: Membrane transport and intracellular motility; NCEBP 2: Evaluation of complex medical interventions; NCEBP 2: Evaluation of complex medical interventions NCMLS 3: Tissue engineering and pathology; ONCOL 3: Translational research NCEBP 2: Evaluation of complex medical interventions
The most important symptom in patients with chronic pancreatitis is pain. This is often difficult to treat. The current treatment consists of, successively, optimal medical treatment, endoscopic intervention and finally surgical intervention. Previous research has indicated that early surgical intervention leads to better pain management and preservation of pancreatic function. Recently, the randomised multicentre 'Early surgery versus optimal current step up practice for chronic-pancreatitis' (ESCAPE) trial was started in order to evaluate whether early surgery provides better reduction of pain in comparison with present treatment. In addition, serious complications, mortality, cost-effectiveness, quality of life, pancreas insufficiency, alternative pain scores, hospital admissions and the number of interventions will be assessed.
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