Subject:
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NCEBP 10: Human Movement & Fatigue NCEBP 6 - Quality of nursing and allied health care DCN PAC - Perception action and control NCEBP 6: Quality of nursing and allied health care NCEBP 6: Quality of nursing and allied health care |
Organization:
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Rehabilitation Paediatrics - OUD tm 2017 IQ Healthcare |
Journal title:
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Neuroscience and Biobehavioral Reviews
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Abstract:
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Although motor problems in Prader-Willi syndrome (PWS) are prominent in infants, and continue into childhood and adulthood, there is little insight into the factors important for clinical management. The literature was reviewed to: (1) provide an overview of the characteristics and prevalence of motor problems and (2) evaluate the effects of growth hormone (GH) treatment and physical training on motor performance. A systematic search revealed 34 papers: 13 on motor performance; 12 on GH treatment; and nine on physical training. In infants, motor development is 30-57% of the normal reference values, and children and adults also have significant problems in skill acquisition, muscle force, cardiovascular fitness, and activity level. GH treatment positively influenced motor performance in infants, children, and adults, although not all studies demonstrated an effect. All studies on physical training demonstrated beneficial effects in PWS patients. We suggest a combination of GH treatment and physical training to be started as soon as possible, especially in infants, to improve motor development as this will positively influence general development.
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