Publication year
2012Source
Nature Reviews. Neurology, 8, 2, (2012), pp. 97-107ISSN
Annotation
01 februari 2012
Publication type
Article / Letter to editor

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Organization
Neurology
Journal title
Nature Reviews. Neurology
Volume
vol. 8
Issue
iss. 2
Page start
p. 97
Page end
p. 107
Subject
DCN MP - Plasticity and memoryAbstract
Positive muscle phenomena arise owing to various forms of spontaneous muscle hyperactivity originating in motor neurons or in the muscle itself. Although they are common in a wide range of neurological and non-neurological diseases, clinical and scientific data on these phenomena are limited, and their presence is sometimes overlooked. This gap in our knowledge hampers effective diagnosis and treatment. In this article, we review the clinical characteristics and approach to diagnosis of the various positive muscle phenomena, and discuss their genetic underpinnings and pathophysiological mechanisms. Finally, we outline an algorithm to discriminate between the different positive muscle phenomena.
This item appears in the following Collection(s)
- Academic publications [227942]
- Faculty of Medical Sciences [86237]
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