Metabolic effects of high altitude trekking in patients with type 2 diabetes
SourceDiabetes Care, 35, 10, (2012), pp. 2018-2020
Article / Letter to editor
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SubjectIGMD 5: Health aging / healthy living; ONCOL 3: Translational research
OBJECTIVE Limited information is available regarding the metabolic effects of high altitude trekking in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Thirteen individuals with type 2 diabetes took part in a 12-day expedition to the summit of Mount Toubkal (altitude, 4,167 m), Morocco, after 6 months of exercise training. Energy expenditure, body weight, blood glucose, fasting insulin, lipids, and HbA(1c) were assessed. RESULTS Training reduced fasting glucose (-0.7 +/- 0.9 mmol/L, P = 0.026) and increased exercise capacity (+0.3 +/- 0.3 W/kg, P = 0.005). High altitude trekking decreased fasting insulin concentrations (-3.8 +/- 3.2 muU/L, P = 0.04), total cholesterol (-0.7 +/- 0.8 mmol/L, P = 0.008), and LDL cholesterol (-0.5 +/- 0.6 mmol/L, P = 0.007). CONCLUSIONS High altitude trekking preceded by exercise training is feasible for patients with type 2 diabetes. It improves blood glucose, lipids, and fasting insulin concentrations, while glucose control is maintained.
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