Publication year
2012Source
Journal of Clinical Gastroenterology, 46, 4, (2012), pp. 321-3ISSN
Publication type
Article / Letter to editor
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Organization
Gastroenterology
Journal title
Journal of Clinical Gastroenterology
Volume
vol. 46
Issue
iss. 4
Page start
p. 321
Page end
p. 3
Subject
IGMD 2: Molecular gastro-enterology and hepatologyAbstract
Refractory medical treatment of Crohn disease-associated toxic megacolon usually requires surgery, which carries substantial morbidity and mortality. We report a case of a woman with steroid and antibiotic-refractory fulminant Crohn colitis and ileitis, complicated by a toxic megacolon, who was successfully treated with infliximab. Infliximab induced rapid clinical response and remission, thereby avoiding emergency (ileo) colectomy. This is the first report of treatment of Crohn disease-associated toxic megacolon with infliximab.
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- Academic publications [238428]
- Faculty of Medical Sciences [90358]
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