Publication year
2012Source
Clinical Science, 122, 7, (2012), pp. 311-22ISSN
Annotation
01 april 2012
Publication type
Article / Letter to editor

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Organization
Physiology
Journal title
Clinical Science
Volume
vol. 122
Issue
iss. 7
Page start
p. 311
Page end
p. 22
Subject
NCEBP 14: Cardiovascular diseases IGMD 5: Health aging / healthy livingAbstract
Thickening of the carotid artery wall has been adopted as a surrogate marker of pre-clinical atherosclerosis, which is strongly related to increased cardiovascular risk. The cardioprotective effects of exercise training, including direct effects on vascular function and lumen dimension, have been consistently reported in asymptomatic subjects and those with cardiovascular risk factors and diseases. In the present review, we summarize evidence pertaining to the impact of exercise and physical activity on arterial wall remodelling of the carotid artery and peripheral arteries in the upper and lower limbs. We consider the potential role of exercise intensity, duration and modality in the context of putative mechanisms involved in wall remodelling, including haemodynamic forces. Finally, we discuss the impact of exercise training in terms of primary prevention of wall thickening in healthy subjects and remodelling of arteries in subjects with existing cardiovascular disease and risk factors.
This item appears in the following Collection(s)
- Academic publications [202652]
- Faculty of Medical Sciences [79967]
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