18F-FDG PET/CT in Detecting Metastatic Infection in Children

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Title:	18F-FDG PET/CT in Detecting Metastatic Infection in Children
Author(s):	Kouijzer, I.J.E. ; Blokhuis, G.J.; Draaisma, J.M.T. ; Oyen, W.J.G. ; Geus-Oei, L.F. de ; Bleeker-Rovers, C.P.
Publication year:	2016
Source:	Clinical Nuclear Medicine, vol. 41, iss. 4, (2016), pp. 278-281
ISSN:	0363-9762
DOI:	https://doi.org/10.1097/RLU.0000000000001119
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/172765
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Subject:	Radboudumc 14: Tumours of the digestive tract RIMLS: Radboud Institute for Molecular Life Sciences Radboudumc 17: Women's cancers RIHS: Radboud Institute for Health Sciences Radboudumc 18: Healthcare improvement science RIHS: Radboud Institute for Health Sciences Radboudumc 4: lnfectious Diseases and Global Health RIHS: Radboud Institute for Health Sciences Radboudumc 9: Rare cancers RIMLS: Radboud Institute for Molecular Life Sciences
Organization:	Internal Medicine Human Genetics Paediatrics - OUD tm 2017 Radiology & Nuclear Medicine
Journal title:	Clinical Nuclear Medicine
Volume:	vol. 41
Issue:	iss. 4
Page start:	p. 278
Page end:	p. 281
Abstract:	PURPOSE OF THE REPORT: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. METHODS: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. RESULTS: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. CONCLUSIONS: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value.