Subject:
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UMCN 1.2: Molecular diagnosis, prognosis and monitoring UMCN 5.2: Endocrinology and reproduction |
Organization:
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Chemical Endocrinology Medical Oncology |
Journal title:
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Breast Cancer Research and Treatment
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Abstract:
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E1AF is a transcription factor involved in regulation of several metastasis-associated genes, and is associated with overexpression of HER2/neu. We were unable to find a clear prognostic value of E1AF expression in human breast cancer. Furthermore, no association of E1AF levels with HER2/neu mRNA levels, hormone receptor status, histological grade, tumor size, or lymph node involvement was found.
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