TY  - THES
AU  - Rood, P.J.T.
PY  - 2020
UR  - https://hdl.handle.net/2066/226627
PB  - [S.l. : s.n.]
TI  - Non pharmacological prevention and treatment of delirium in the intensive care unit
N1  - Radboud University, 1 december 2020
N1  - Promotores : Pickkers, P., Vermeulen, H. 
Co-promotor : Boogaard, M.H.W.A. van den
ER  - 
TY  - THES
AU  - Koch, R.M.
PY  - 2019
UR  - https://hdl.handle.net/2066/207783
PB  - [S.l. : s.n.]
TI  - Differential pathogen-host interactions
N1  - Radboud University, 25 oktober 2019
N1  - Promotor : Pickkers, P. 
Co-promotores : Kox, M., Jonge, M.I. de
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/207783/207783.pdf?sequence=1
ER  - 
TY  - THES
AU  - Geven, C.B.C.A.G.
PY  - 2019
UR  - https://hdl.handle.net/2066/201197
PB  - [S.l. : s.n.]
TI  - Targeting adrenomedullin in sepsis
N1  - Radboud University, 15 maart 2019
N1  - Promotor : Pickkers, P. 
Co-promotor : Kox, M.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/201197/201197.pdf?sequence=1
ER  - 
TY  - THES
AU  - Kiers, H.D.
PY  - 2019
UR  - https://hdl.handle.net/2066/200678
PB  - [S.l. : s.n.]
TI  - Oxygen and platelets. Translational studies on therapeutic targets for immunomodulation
N1  - Radboud University, 4 februari 2019
N1  - Promotores : Pickkers, P., Scheffer, G.J. 
Co-promotor : Kox, M.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/200678/200678.pdf?sequence=1
ER  - 
TY  - THES
AU  - Brule, J.M.D. van den
PY  - 2019
UR  - https://hdl.handle.net/2066/200690
PB  - [S.l. : s.n.]
TI  - Cerebral hemodynamics. After cardiac arrest, in sepsis and in the human endotoxemia model
N1  - Radboud University, 21 februari 2019
N1  - Promotor : Hoeven, J.G. van der 
Co-promotor : Hoedemaekers, C.W.E.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/200690/200690.pdf?sequence=1
ER  - 
TY  - THES
AU  - Witjes, M.
PY  - 2019
UR  - https://hdl.handle.net/2066/206200
PB  - [S.l. : s.n.]
TI  - Organ donation in the Netherlands; how to improve donor identification and family consent
N1  - Radboud University, 4 september 2019
N1  - Promotor : Hoeven, J.G. van der 
Co-promotores : Abdo, W.F., Jansen, N.E.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/206200/206200.pdf?sequence=1
ER  - 
TY  - THES
AU  - Wassenaar, A.
PY  - 2018
SN  - 9789492896
UR  - https://hdl.handle.net/2066/190667
PB  - [S.l. : s.n.]
TI  - Prediction and non-pharmacological prevention of delirium in the intensive care unit
N1  - Radboud University, 16 mei 2018
N1  - Promotores : Pickkers, P., Schoonhoven, L. 
Co-promotor : Boogaard, M. van den
PS  - 242 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/190667/190667.pdf?sequence=1
ER  - 
TY  - THES
AU  - Simons, K.S.
PY  - 2018
SN  - 9789492896414
UR  - https://hdl.handle.net/2066/194289
PB  - [S.l. : s.n.]
TI  - The ICU environment. Impact of light and noise exposure on critically ill patients
N1  - Radboud University, 14 september 2018
N1  - Promotores : Pickkers, P., Hoeven, J.G. van der 
Co-promotores : Boogaard, M. van den, Jager, C.P.C. de
PS  - 200 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/194289/194289.pdf?sequence=1
ER  - 
TY  - THES
AU  - Kolk, B.M. van der
PY  - 2018
SN  - 9789463751537
UR  - https://hdl.handle.net/2066/196862
PB  - [S.l. : s.n.]
TI  - Development, implementation and evaluation of high-risk surgery related clinical pathways in the intensive care: effects of a process intervention
N1  - Radboud University, 15 november 2018
N1  - Promotores : Pickkers, P., Laarhoven, C.J.H.M. van 
Co-promotor : Boogaard, M. van den
PS  - 168 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/196862/196862.pdf?sequence=1
ER  - 
TY  - THES
AU  - Haerkens, M.H.T.M.
PY  - 2017
SN  - 9789077245668
UR  - https://hdl.handle.net/2066/162528
AB  - Despite modern equipment, increasing emphasis on patient safety, and excellent training facilities medical care frequently results in unintentional harm to patients. Human Factors (HF) appear to play an important role in adverse events, especially in high risk clinical departments. A sound safety climate is considered essential, as it is positively related to safety outcomes.
This thesis focused on HF and critical team performance in clinical medicine.
First, an overview of existing literature, our healthcare CRM training curriculum, and a three-phase implementation structure were described.
An open source safety climate assessment tool (Safety Attitudes Questionnaire-NL) was validated and an aviation-derived HF awareness / team concept (Crew Resource Management - CRM)  was adapted to the clinical setting. Additionally, CRM was implemented in multiple hospital departments and its impact on patient safety assessed.
A study into the impact of a CRM-intervention in a large ICU yielded an association of CRM with a reduction in serious complications, and lower mortality, in critically ill patients. Also, safety climate improved.
CRM implementation in the Trauma Room of a level 1 Emergency Department (ED) was associated with an improved safety climate, although the time spent by trauma patients in the ED increased.
CRM implementation in 17 high-risk clinical departments was associated with an improved safety climate. The results were related to perceived implementation success factors as well as threats to success. Also, points for improvement formulated by healthcare providers and potential barriers to transfer of CRM training to the work floor were provided.
Finally all research findings, current issues and future perspectives for healthcare CRM are discussed. The challenge of adapting the medical organizational context to fully integrate HF principles into daily health operations was described and operational, educational, standardization and inspectorate/judicial aspects of this challenge identified.
PB  - [S.l. : s.n.]
TI  - Human factors and team performance
N1  - Radboud University, 19 januari 2017
N1  - Promotores : Hoeven, J.G. van der, Pickkers, P. 
Co-promotor : Kox, M.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/162528/162528.pdf?sequence=1
ER  - 
TY  - THES
AU  - Peters, E.
PY  - 2017
SN  - 9789492380333
UR  - https://hdl.handle.net/2066/169251
PB  - [S.l.] : s.l. ; s.n.
TI  - Alkaline phosphatase to treat septic acute kidney injury
N1  - Radboud University, 19 mei 2017
N1  - Promotores : Pickkers, P., Masereeuw (UU), R.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/169251/169251.pdf?sequence=1
ER  - 
TY  - THES
AU  - Doorduin, J.
PY  - 2017
SN  - 9789082678420
UR  - https://hdl.handle.net/2066/173271
PB  - [S.l. : s.n.]
TI  - Diaphragm dysfunction in critically ill patients. From monitoring to interventions
N1  - Radboud University, 22 juni 2017
N1  - Promotores : Hoeven, J.G. van der, Heunks, L.M.A. 
Co-promotor : Hees, H.W.H. van
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/173271/173271.pdf?sequence=1
ER  - 
TY  - THES
AU  - Dorresteijn, M.J.
PY  - 2016
SN  - 9789462334250
UR  - https://hdl.handle.net/2066/161236
PB  - [S.l. : s.n.]
TI  - Heme oxygenase and inflammation
N1  - Radboud University, 16 december 2016
N1  - Promotores : Pickkers, P., Hoeven, J.G. van der 
Co-promotor : Wagener, F.A.D.T.G.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/161236/161236.pdf?sequence=1
ER  - 
TY  - THES
AU  - Eijk, L.T.G.J. van
PY  - 2016
SN  - 9789463320658
UR  - https://hdl.handle.net/2066/160309
PB  - [S.l. : s.n.]
TI  - Iron and innate immunity
N1  - RU Radboud Universiteit, 17 oktober 2016
N1  - Promotores : Pickkers, P., Swinkels, D.W. 
Co-promotor : Kox, M.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/160309/160309.pdf?sequence=1
ER  - 
TY  - THES
AU  - Leentjens, J.
PY  - 2016
SN  - 9789462599758
UR  - https://hdl.handle.net/2066/150171
PB  - [S.l. : s.n.]
TI  - Immunomodulation in severe infections
N1  - Radboud Universiteit Nijmegen, 8 januari 2016
N1  - Promotores : Pickkers, P., Netea, M.G. 
Co-promotor : Kox, M.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/150171/150171.pdf?sequence=1
ER  - 
TY  - THES
AU  - Bisschops, L.L.A.
PY  - 2015
SN  - 9789462596207
UR  - https://hdl.handle.net/2066/139518
PB  - [S.l. : s.n.]
TI  - Hypothermia and rewarming after cardiac arrest. Dynamics in cerebral blood flow, cerebral metabolism and inflammation
N1  - Radboud Universiteit Nijmegen, 21 april 2015
N1  - Promotor : Hoeven, J.G. van der 
Co-promotor : Hoedemaekers, C.W.E.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/139518/139518.pdf?sequence=1
ER  - 
TY  - THES
AU  - Santen, S. van
PY  - 2015
UR  - https://hdl.handle.net/2066/141369
PB  - [S.l. : s.n.]
TI  - Iron homeostasis in inflammation, malaria and pregnancy
N1  - Radboud Universiteit Nijmegen, 16 juni 2015
N1  - Promotores : Ven, A.J.A.M. van der, Swinkels, D.W. 
Co-promotor : Mast, Q. de
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/141369/MMUBN000001_107296662X.pdf?sequence=1
ER  - 
TY  - THES
AU  - Simmes, W.M.C.
PY  - 2014
SN  - 9789462592568
UR  - https://hdl.handle.net/2066/129681
PB  - [S.l. : s.n.]
TI  - Critically ill, well assessed. Evaluation of the rapid response system in a university medical center
N1  - Radboud Universiteit Nijmegen, 26 september 2014
N1  - Promotor : Hoeven, J.G. van der 
Co-promotores : Schoonhoven, L., Mintjes-de Groot, A.J.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/129681/129681.pdf?sequence=1
ER  - 
TY  - THES
AU  - Nusmeier, A.
PY  - 2013
SN  - 9789057501135
UR  - https://hdl.handle.net/2066/117512
PB  - [S.l. : s.n.]
TI  - Advanced hemodynamic monitoring in children
N1  - Radboud Universiteit Nijmegen, 28 november 2013
N1  - Promotor : Hoeven, J.G. van der 
Co-promotores : Lemson, J., Boode, W.P. de
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/117512/117512.pdf?sequence=1
ER  - 
TY  - THES
AU  - Moviat, M.
PY  - 2013
UR  - https://hdl.handle.net/2066/101054
PB  - [S.l. : s.n.]
TI  - Stewart approach of acid-base disorders in Intensive Care patients
N1  - Radboud Universiteit Nijmegen, 18 januari 2013
N1  - Promotores : Pickkers, P., Hoeven, J.G. van der 
Co-promotor : Voort, P.J.H. van der
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/101054/101054.pdf?sequence=1
ER  - 
TY  - THES
AU  - Boogaard, M.H.W.A. van den
PY  - 2012
SN  - 9789461908131
UR  - https://hdl.handle.net/2066/93528
PB  - [S.l. : s.n.]
TI  - Delirium in intensive care patients; detection, impact, prediction, prevention and biomarkers.
N1  - Radboud Universiteit Nijmegen, 2 april 2012
N1  - Promotores : Pickkers, P., Hoeven, J.G. van der, Achterberg, T. van 
Co-promotor : Schoonhoven, L.
PS  - 253 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/93528/93528.pdf?sequence=1
ER  - 
TY  - THES
AU  - Ramakers, B.P.C.
PY  - 2012
UR  - https://hdl.handle.net/2066/108603
PB  - [S.l. : s.n.]
TI  - Adenosine and immunomodulation
N1  - Radboud Universiteit Nijmegen, 16 november 2012
N1  - Promotores : Pickkers, P., Smits, P.A.B.M., Hoeven, J.G. van der 
Co-promotor : Riksen, N.P.
PS  - 241 p.
ER  - 
TY  - THES
AU  - Tromp, M.
PY  - 2012
SN  - 9789462032019
UR  - https://hdl.handle.net/2066/100891
PB  - [S.l. : s.n.]
TI  - Improving the care for patients with sepsis. Prevention, diagnosis and treatment
N1  - Radboud Universiteit Nijmegen, 14 december 2012
N1  - Promotores : Pickkers, P., Kullberg, B.J., Achterberg, T. van 
Co-promotor : Hulscher, M.E.J.L.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/100891/100891.pdf?sequence=1
ER  - 
TY  - THES
AU  - Kox, M.
PY  - 2011
SN  - 9789081798204
UR  - https://hdl.handle.net/2066/91436
PB  - [S.l. : s.n.]
TI  - The cholinergic anti-inflammatory pathway. In vitro, animal and human studies.
N1  - Radboud Universiteit Nijmegen, 17 november 2011
N1  - Promotores : Pickkers, P., Hoeven, J.G. van der 
Co-promotor : Hoedemaekers, C.W.E.
PS  - 319 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/91436/91436.pdf?sequence=1
ER  - 
TY  - THES
AU  - Lemson, J.
PY  - 2010
SN  - 9789057501104
UR  - https://hdl.handle.net/2066/82615
PB  - [S.l. : s.n.]
TI  - Advanced hemodynamic monitoring in critically ill children.
N1  - Radboud Universiteit Nijmegen, 14 oktober 2010
N1  - Promotores : Hoeven, J.G. van der, Scheffer, G.J.
PS  - 227 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/82615/82615.pdf?sequence=1
ER  - 
TY  - THES
AU  - Draisma, A.
PY  - 2010
SN  - 9789090248714
UR  - https://hdl.handle.net/2066/74871
PB  - [S.l. : s.n.]
TI  - Endotoxin Tolerance. Explorative studies in humans.
N1  - RU Radboud Universiteit Nijmegen, 7 januari 2010
N1  - Promotor : Hoeven, J.G. van der 
Co-promotor : Pickkers, P.
PS  - 149 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/74871/74871.pdf?sequence=1
ER  - 
TY  - THES
AU  - Haren, F.M.P. van
PY  - 2010
SN  - 9789090252377
UR  - https://hdl.handle.net/2066/76176
PB  - [S.l. : s.n.]
TI  - Novel hemodynamic therapies in septic shock; Effects on circulation, organ perfusion and immune system.
N1  - RU Radboud Universiteit Nijmegen, 22 april 2010
N1  - Promotores : Hoeven, J.G. van der, Sleigh, J., Pickkers, P.
PS  - 186 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/76176/76176.pdf?sequence=1
ER  - 
TY  - THES
AU  - Halbertsma, F.J.
PY  - 2008
SN  - 9789076014197
UR  - https://hdl.handle.net/2066/70825
PB  - [S.l. : s.n.]
TI  - Ventilator Induced Lung Injury in Children in the Intensive Care: Experimental and Clinical Studies.
N1  - RU Radboud Universiteit Nijmegen, 31 oktober 2008
N1  - Promotores : Hoeven, J.G. van der, Scheffer, G.J. 
Co-promotor : Pickkers, P.
PS  - 147 p.
ER  - 
TY  - THES
AU  - Schouten, J.A.
PY  - 2006
SN  - 9076316872
UR  - https://hdl.handle.net/2066/50931
PB  - [S.l. : s.n.]
TI  - Improving the quality of antibiotic use for respiratory tract infections in hospitals.
N1  - RU Radboud Universiteit Nijmegen, 29 augustus 2006
N1  - Promotores : Meer, J.W.M. van der, Grol, R.P.T.M., Kullberg, B.J. 
Co-promotor : Hulscher, M.E.J.L.
PS  - 192 p.
ER  - 
TY  - THES
AU  - Neeleman, C.
PY  - 2004
SN  - 9090182462
UR  - https://hdl.handle.net/2066/58711
PB  - [S.l. : s.n.]
TI  - Streptococcus Pneumoniae. Aspects of pathogenis and resistance.
N1  - KUN Katholieke Universiteit Nijmegen, 9 juli 2004
N1  - Promotores : Meer, J.W.M. van der, Hoeven, J.G. van der 
Co-promotores : Deuren, M. van, Mouton, J.W.
PS  - V, 145 p.
ER  -