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MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia

Prange, K.H.M.; Mandoli, A.; Kuznetsova, T.; Wang, S. ; Sotoca, A.M.; Marneth, A.E.; Van der Reijden, B.A.; Stunnenberg, H. ; Martens, J.H.A.

2017, Article / Letter to editor (Oncogene, (2017), pp. 1-11)
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis

van den Boom, V.; Maat, H.; Geugien, M.; Lopez, A.R.; Sotoca, A.M.; Jaques, J.; Brouwers-Vos, A.Z.; Fusetti, F.; Groen, R.W.J.; Yuan, H.P.; Martens, A.C.M.; Stunnenberg, H.G. ; Vellenga, E.; Martens, J.H.A. ; Schuringa, J.J. et al. sine al.

2016, Article / Letter to editor (Cell Reports, vol. 14, iss. 2, (2016), pp. 332-346)
The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia

Sotoca Covaleda, A.M.; Prange, K.H.M.; Reijnders, B.; Mandoli, A.; Nguyen, L.N.; Stunnenberg, H.G. ; Martens, J.H.A.

2015, Article / Letter to editor (Oncogene, vol. 35, (2015), pp. 1965-1976)
Epidermal growth factor mutant with wild-type affinity for both ErbB1 and ErbB3

Wingens, M. ; Jacobs-Oomen, S. ; Woning, S.P. van der ; Stortelers, C.; Zoelen, E.J.J. van

2006, Article / Letter to editor (Biochemistry, vol. 45, iss. 14, (2006), pp. 4703-4710)
Negative constraints underlie the ErbB specificity of epidermal growth factor-like ligands

Woning, S.P. van der ; Rotterdam, W. van ; Nabuurs, S.B. ; Venselaar, H. ; Jacobs-Oomen, S. ; Wingens, M. ; Vriend, G. ; Stortelers, C.; Zoelen, E.J.J. van

2006, Article / Letter to editor (Journal of Biological Chemistry, vol. 281, iss. 52, (2006), pp. 40033-40040)
Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts

Vaes, B.L.T. ; Dechering, K.J. ; Someren, E.P. van ; Hendriks, J.M.; Ven, C.J. van de; Feijen, A.; Mummery, C.L.; Reinders, M.J.; Olijve, W. ; Zoelen, E.J.J. van ; Steegenga, W.T. et al. sine al.

2005, Article / Letter to editor (Bone, vol. 36, iss. 5, (2005), pp. 803-811)
Identification of novel regulators associated with early-phase osteoblast differentiation.

Jong, D.S. de; Vaes, B.L.T. ; Dechering, K.J. ; Feijen, A.; Hendriks, J.M.; Wehrens, H.R.M.J. ; Mummery, C.L.; Zoelen, E.J.J. van ; Olijve, W. ; Steegenga, W.T.

2004, Article / Letter to editor (Journal of Bone and Mineral Research, vol. 19, iss. 6, (2004), pp. 947-958)
Regulation of Notch signaling genes during BMP2-induced differentiation of osteoblast precursor cells.

Jong, D.S. de; Steegenga, W.T. ; Hendriks, J.M.; Zoelen, E.J.J. van ; Olijve, W. ; Dechering, K.J.

2004, Article / Letter to editor (Biochemical and Biophysical Research Communications, vol. 320, iss. 1, (2004), pp. 100-107)
Selective formation of ErbB-2/ErbB-3 heterodimers depends on the ErbB-3 affinity of epidermal growth factor-like ligands

Stortelers, C.; Woning, S.P. van der ; Jacobs-Oomen, S. ; Wingens, M. ; Zoelen, E.J.J. van

2003, Article / Letter to editor (Journal of Biological Chemistry, vol. 278, (2003), pp. 12055-12063)
Structural analysis of an epidermal growth factor/transforming growth factor-alpha chimera with unique ErbB binding specificity

Wingens, M. ; Walma, T. ; Ingen, H. van ; Stortelers, C.; Leeuwen, J.E.M. van ; Zoelen, E.J.J. van ; Vuister, G.W.

2003, Article / Letter to editor (Journal of Biological Chemistry, vol. 278, iss. 40, (2003), pp. 39114-39123)
A regulating element essential for PDGRFA transcription is recognized by neural tube defect-associated PRX homeobox transcription factors

Joosten, P.H.L.J.; Toepoel, M.; Oosterhout, D. van; Afink, G.B. ; Zoelen, E.J.J. van

2002, Article / Letter to editor (Biochimica et Biophysica Acta. Molecular Basis of Disease, vol. 1588, (2002), pp. 254-260)
Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development

Vaes, B.L.T. ; Dechering, K.J. ; Feijen, A.; Hendriks, J.M.A.; Lefevre, C.; Mummery, C.L.; Olijve, W. ; Zoelen, E.J.J. van ; Steegenga, W.T.

2002, Article / Letter to editor (Journal of Bone and Mineral Research, vol. 17, (2002), pp. 2106-2118)
Epidermal growth factor contains both positive and negative determinants for interaction with ErbB2/ErbB-3 heterodimers

Stortelers, C.; Poll, M.L.M. van de ; Lenferink, A.E.G. ; Gadellaa, M.M.; Zoelen, C. van; Zoelen, E.J.J. van

2002, Article / Letter to editor (Biochemistry, vol. 41, (2002), pp. 4292-4301)
Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display

Stortelers, C.; Souriau, C.; Liempt, E. van; Poll, M.L.M. van de ; Zoelen, E.J.J. van

2002, Article / Letter to editor (Biochemistry, vol. 41, (2002), pp. 8732-8741)
Fenamates: a novel class of reversible gap junction blockers.

Harks, G.A.; Roos, A.D.G. de ; Peters, P.H.J.; Haan, L. de; Brouwer, A.P.M. de ; Ypey, D.L. ; Zoelen, E.J.J. van ; Theuvenet, A.P.R.

2001, Article / Letter to editor (Journal of Pharmacology and Experimental Therapeutics, vol. 298, iss. 3, (2001), pp. 1033-1041)
Antiestrogens specifically upregulate bone morphogenetic protein-4 promoter activity in human osteoblastic cells

Wijngaard, A. van de; Mulder, W.R.; Dijkema, R.; Boersma, C.J.C.; Mosselman, S.; Zoelen, E.J.J. van ; Olijve, W.

2000, Article / Letter to editor (Molecular Endocrinology, vol. 14, (2000), pp. 623-633)
Non-linear antigenic regions in epidermal growth factor (EGF) and transforming growth factor alpha (TGFalpha) studied by EGF-TGFalpha chimaeras

Poll, M.L.M. van de ; Rotterdam, W. van ; Gadellaa, M.M.; Stortelers, C.; Vught, M.J.H. van; Zoelen, E.J.J. van

2000, Article / Letter to editor (Biochemical Journal, vol. 349, (2000), pp. 267-274)
Superagonistic activation of ErbB-1 by EGF-related growth factors with enhanced association and dissociation rate constants

Lenferink, A.E.G. ; Zoelen, E.J.J. van ; Vugt, M. van; Grothe, S.; Rotterdam, W. van ; Poll, M.L.M. van de ; O'Connor-McCourt, M.D.

2000, Article / Letter to editor (Journal of Biological Chemistry, vol. 275, (2000), pp. 26748-26753)
The EGF domain: requirements for binding to receptors of the ErbB familly

Zoelen, E.J.J. van ; Stortelers, C.; Lenferink, A.E.G. ; Poll, M.L.M. van de

2000, Article / Letter to editor (Vitamins and Hormones, vol. 59, (2000), pp. 99-131)
Central role of epidermal growth factor (EGF) receptor density in anchorage-independent growth of normal rad kidney cells

Lahaye, D.H.T.P.; Camps, M.; Zoelen, E.J.J. van

1999, Article / Letter to editor (FEBS Letters, vol. 446, (1999), pp. 256-260)
Homeobox proteins as signal transfuction intermediates in regulation of NCAM expression by recombinant human bone morphogenetic protein-2 in osteoblast-like cells

Boersma, C.J.C.; Bloemen, M. ; Hendriks, J.M.A.; Berkel, E.A.T. van; Olijve, W. ; Zoelen, E.J.J. van

1999, Article / Letter to editor (Molecular Cell Biology Research Communications, vol. 1, (1999), pp. 117-124)
Phenotypic transformation of normal rad kidney fibroblasts by endothelin-1. Different mode of action from lysophosphatidic acid, bradykinin, and prostaglandin F2alpha

Lahaye, D.H.T.P.; Walboomers, X.F. ; Peters, P.H.J.; Theuvenet, A.P.R. ; Zoelen, E.J.J. van

1999, Article / Letter to editor (Biochimica et Biophysica Acta. Molecular Cell Research, vol. 1449, (1999), pp. 107-118)
Altered regulation of PDGFRa transcription in vitro by spina bifida associated mutant Pax1 proteins

Joosten, P.H.L.J.; Hol, F.A. ; Beersum, S.E.C. van ; Peters, H.; Hamel, B.C.J. ; Afink, G.B. ; Zoelen, E.J.J. van ; Mariman, E.C.M.

1998, Article / Letter to editor (Proceedings of the National Academy of Sciences USA, vol. 95, (1998), pp. 14459-14463)
Synchronized calcium spiking resulting from spontaneous calcium action potentials in monolayers of NRK fibroblasts

Roos, A.D.G. de ; Willems, P.H.G.M. ; Peters, P.H.J.; Zoelen, E.J.J. van ; Theuvenet, A.P.R.

1997, Article / Letter to editor (Cell Calcium, vol. 22, (1997), pp. 195-207)
Synchronized Ca2+ signaling by intercellular propagation of Ca2+ action potentials in NRK fibroblasts

Roos, A.D.G. de ; Willems, P.H.G.M. ; Zoelen, E.J.J. van ; Theuvenet, A.P.R.

1997, Article / Letter to editor (American Journal of Physiology, vol. 273, (1997), pp. C1900-C1907)
Fine mapping of the human bone morphogenetic protein-4 (BMP-4) gene to chromosome 14q22-q23 by in situ hybridization

Wijngaard, A. van de; Olde Weghuis, D.E.M. ; Boersma, C.J.C.; Zoelen, E.J.J. van ; Geurts van Kessel, A.H.M. ; Olijve, W.

1995, Article / Letter to editor (Genomics : International Journal of Gene Mapping and Nucleotide Sequencing Emphasizing Analyses of the Human and Other Complex Genomes, vol. 27, (1995), pp. 559-560)
A single amino acid exchange, Arg 45 to Ala, generates an epidermal growth facor (EGF) mutant with high affinity for the chicken EGF receptor

Poll, M.L.M. van de ; Lenferink, A.E.G. ; Vugt, A.H.M. van; Jacobs, J.J.L.; Janssen, J.W.H.; Joldersma, M.; Zoelen, E.J.J. van

1995, Article / Letter to editor (Journal of Biological Chemistry, vol. 270, (1995), pp. 22337-22343)

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