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MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia

Prange, K.H.M.; Mandoli, A.; Kuznetsova, T.; Wang, S. ; Sotoca, A.M.; Marneth, A.E.; Van der Reijden, B.A.; Stunnenberg, H. ; Martens, J.H.A.

2017, Article / Letter to editor (Oncogene, (2017), pp. 1-11)
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis

van den Boom, V.; Maat, H.; Geugien, M.; Lopez, A.R.; Sotoca, A.M.; Jaques, J.; Brouwers-Vos, A.Z.; Fusetti, F.; Groen, R.W.J.; Yuan, H.P.; Martens, A.C.M.; Stunnenberg, H.G. ; Vellenga, E.; Martens, J.H.A. ; Schuringa, J.J. et al. sine al.

2016, Article / Letter to editor (Cell Reports, vol. 14, iss. 2, (2016), pp. 332-346)
The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia

Sotoca Covaleda, A.M.; Prange, K.H.M.; Reijnders, B.; Mandoli, A.; Nguyen, L.N.; Stunnenberg, H.G. ; Martens, J.H.A.

2015, Article / Letter to editor (Oncogene, vol. 35, (2015), pp. 1965-1976)
Cytotoxic and genotoxic activity of fisetin (3, 3 ', 4 ', 7-tetrahydroxyflavone) in an osteosarcoma in vitro model

Oliveira, J.M.P.F. de; Oliveira, H.; Pinho, S.; Pimentel, F.; Almeida, L.; Zoelen, E.J.J. van ; Santos, C. dos

2014, Article / Letter to editor (Planta Medica, vol. 80, iss. 16, (2014), pp. 1412, article P1L4)
Analysis of stably expressed genes with low-dose etoposide for toxicological studies in osteosarcoma

Oliveira, J.M.P.F. de; Almeida, L.; Pimentel, F.; Zoelen, E.J.J. van ; Santos, C. dos

2014, Article / Letter to editor (Planta Medica, vol. 80, iss. 16, (2014), pp. 1451-1452, article P1L127)
Cytoplasmic Overexpression of HER2: a Key Factor in Colorectal Cancer

Blok, E.J.; Kuppen, P.J.; Leeuwen, J.E. van ; Sier, C.F.

2013, Article / Letter to editor (Clinical Medicine Insights: Oncology, vol. 7, (2013), pp. 41-51)
Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risks

Rietjens, I.M.C.M.; Sotoca Covaleda, A.M.; Vervoort, J.; Louisse, J.

2013, Article / Letter to editor (Molecular Nutrition & Food Research (Formerly Nahrung/Food), vol. 57, iss. 1, (2013), pp. 100-113)
Cbl and Itch binding sites in ERBB4 CYT-1 and CYT-2 mediate K48- and K63-polyubiquitination, respectively

Meijer, I.M.J.; Rotterdam, W. van ; Zoelen, E.J.J. van ; Leeuwen, J.E.M. van

2013, Article / Letter to editor (Cellular Signalling, vol. 25, iss. 2, (2013), pp. 470-478)
The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation

Meijer, I.M.; Kerperien, J.; Sotoca, A.M.; Zoelen, Joop van ; Leeuwen, J.E. van

2013, Article / Letter to editor (Cellular Signalling, vol. 25, iss. 4, (2013), pp. 919-930)
Identification of Novel Bacterial M.SssI DNA Methyltransferase Inhibitors

Hupkes, M.; Azevedo, R.; Jansen, H.; Zoelen, Joop van ; Dechering, K.J.

2013, Article / Letter to editor (Journal of Biomolecular Screening, vol. 18, iss. 3, (2013), pp. 348-355)
Comparative proteome approach demonstrates that platelet-derived growth factor C and D efficiently induce proliferation while maintaining multipotency of hMSCs

Sotoca, A.M.; Roelofs-Hendriks, J.; Boeren, S.; Kraan, P.M. van der ; Vervoort, J.; Zoelen, E.J.J. van ; Piek, E.

2013, Article / Letter to editor (Experimental Cell Research, vol. 319, iss. 17, (2013), pp. 2649-2662)
Inference of dynamical gene-regulatory networks based on time-resolved multi-stimuli multi-experiment data applying NetGenerator V2.0

Weber, M.; Henkel, S.; Vlaic, S.; Guthke, R.; Zoelen, Joop van ; Driesch, D.

2013, Article / Letter to editor (BMC Systems Biology, vol. 7, iss. 1, (2013), pp. 1-16)
Dynamic modelling of microrna regulation during mesenchymal stem cell differentiation

Weber, M.; Sotoca, A.M.; Kupfer, P.; Guthke, R.; Zoelen, E.J.J. van

2013, Article / Letter to editor (BMC Systems Biology, vol. 7, iss. 1, (2013), pp. 124)
Inference of dynamical gene-regulatory networks based on time-resolved multi-stimuli multi-experiment data applying NetGenerator V2.0

Weber, M.; Henkel, S.G.; Vlaic, S.; Guthke, R.; Zoelen, Joop van ; Driesch, D.

2013, Article / Letter to editor (BMC Systems Biology, vol. 7, iss. 1, (2013), pp. 1(1)-1(28))
Activation of the antioxidant response in methionine deprived human cells results in an HSF1-independent increase in HSPA1A mRNA levels

Hensen, S.M.M.; Heldens, L. ; Enckevort, C.M.W. van; Genesen, S.T. van ; Pruijn, G.J.M. ; Lubsen, N.H.

2013, Article / Letter to editor (Biochimie, vol. 95, iss. 6, (2013), pp. 1245-1251)
A delayed antioxidant response in heat-stressed cells expressing a non-DNA binding HSF1 mutant

Hensen, S.M.; Heldens, L. ; Genesen, S.T. van ; Pruijn, G.J.M. ; Lubsen, N.H.

2013, Article / Letter to editor (Cell Stress & Chaperones, vol. 18, iss. 4, (2013), pp. 455-473)
Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH

Meijer, I.M.J.; Rotterdam, W. van ; Zoelen, Joop van ; Leeuwen, J.E. van

2012, Article / Letter to editor (Cellular Signalling, vol. 24, (2012), pp. 1981-1988)
Catabolic Factors and Osteoarthritis-Conditioned Medium Inhibit Chondrogenesis of Human Mesenchymal Stem Cells

Heldens, G.; Davidson, E.N; Vitters, E.L; Schreurs, B.W; Piek, E. ; Berg, W.B. van den ; Kraan, P.M. van der

2012, Article / Letter to editor (Tissue Engineering Part A, vol. 18, iss. 1-2, (2012), pp. 45-54)
Role of Trpc channels, Stim1 and Orai1 in PGF(2 alpha)-induced calcium signaling in NRK fibroblasts

Almirza, W.H.M.A.; Peters, P.H.J.; Zoelen, E.J.J. van ; Theuvenet, A.P.R.

2012, Article / Letter to editor (Cell Calcium, vol. 51, iss. 1, (2012), pp. 12-21)
Heat shock factor 1 is inactivated by amino acid deprivation

Hensen, S.M.M.; Heldens, L. ; Enckevort, C.M.W. van; Genesen, S.T. van ; Pruijn, G.J.M. ; Lubsen, N.H.

2012, Article / Letter to editor (Cell Stress & Chaperones, vol. 17, iss. 6, (2012), pp. 743-755)
Non-glycosylated BMP-2 can induce ectopic bone formation at lower concentrations compared to glycosylated BMP-2.

Watering, F.C.J. van de ; Beucken, J.J.J.P van den ; Woning, S.P. van der ; Briest, A.; Eek, A. ; Qureshi, H.; Winnubst, L.; Boerman, O.C. ; Jansen, J.B.M.J.

2012, Article / Letter to editor (Journal of Controlled Release, vol. 159, iss. 1, (2012), pp. 69-77)
Analysis of the melanotrope cell neuroendocrine interface in two amphibian species, Rana ridibunda and Xenopus laevis: A celebration of 35 years of collaborative research

Jenks, B.G. ; Galas, L.; Kuribara, M. ; Desrues, L.; Kidane, A.H. ; Vaudry, H.; Scheenen, W.J.J.M. ; Roubos, E.W. ; Tonon, M.C.

2011, Article / Letter to editor (General and Comparative Endocrinology, vol. 170, iss. 1, (2011), pp. 57-67)
DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation

Hupkes, M.; Someren, E.P. van ; Middelkamp, S.H.A.; Piek, E. ; Zoelen, Joop van ; Dechering, K.J.

2011, Article / Letter to editor (Biochimica et Biophysica Acta. Molecular Cell Research, vol. 1813, iss. 5, (2011), pp. 839-849)
Epigenetics: DNA demethylation promotes skeletal myotube maturation

Hupkes, M.; Jonsson, M.K.; Scheenen, W.J.J.M. ; Rotterdam, W. van ; Sotoca Covaleda, A.M.; Someren, E.P. van ; Heyden, M.A. van der; Veen, T.A. van; Ravestein-Van Os, R.I. van; Bauerschmidt, S.; Piek, E. ; Ypey, D.L. ; Zoelen, E.J.J. van ; Dechering, K.J. et al. sine al.

2011, Article / Letter to editor (The Faseb Journal, vol. 25, iss. 11, (2011), pp. 3861-3872)
Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis

Vrolix, K.; Niks, E.H.; Panse, R. Le; Ostaijen-ten Dam, M.M. van; Muris, A.H.; Zijde, C.M. Jol-van der; Tol, M.J.D. van; Losen, M.; Molenaar, P.C.; Zoelen, E.J.J. van ; Berrih-Aknin, S.; Baets, M.H. De; Verschuuren, J.; Martinez-Martinez, P. et al. sine al.

2011, Article / Letter to editor (Journal of Neuroimmunology, vol. 232, iss. 1-2, (2011), pp. 158-165)
Extracellular-signal regulated kinase regulates production of pro-opiomelanocortin in pituitary melanotroph cells.

Kuribara, M. ; Kidane, A.H. ; Vos, G.A.; Gouw, D. de; Roubos, E.W. ; Scheenen, W.J.J.M. ; Jenks, B.G.

2011, Article / Letter to editor (Journal of Neuroendocrinology, vol. 23, iss. 3, (2011), pp. 261-268)
A dnajb chaperone subfamily with hdac-dependent activities suppresses toxic protein aggregation

Hageman, J.; Rujano, M.A.; Waarde, M. van; Kakkar, V.; Dirks, R.P.; Govorukhina, N.; Oosterveld-Hut, H.M.J.; Lubsen, N.H. ; Kampinga, H.H.

2010, Article / Letter to editor (Molecular Cell, vol. 37, iss. 3, (2010), pp. 355-369)
Beyond single p-value cut-offs: Methods to improve decision making in GO enrichment analysis of microarray experiments

Haan, J.R. de ; Wehrens, H.R.M.J. ; Bauerschmidt, S.; Schaik, R.C. Van; Piek, E. ; Buydens, L.M.C.

2010, Article / Letter to editor (Online Journal of Bioinformatics, vol. 11, iss. 1, (2010), pp. 1-18)
Effects of the EGFR Inhibitor Erlotinib on Magnesium Handling.

Dimke, H. ; Wijst, J.A.J. van der ; Alexander, T. ; Meijer, I.M.J.; Mulder, G.M.; Goor, H. van ; Tejpar, S.; Hoenderop, J.G.J. ; Bindels, R.J.M.

2010, Article / Letter to editor (Journal of the American Society of Nephrology, vol. 21, iss. 8, (2010), pp. 1309-1316)
Osteo-transcriptomics of human mesenchymal stem cells: Accelerated gene expression and osteoblast differentiation induced by vitamin d reveals c-myc as an enhancer of bmp2-induced osteogenesis

Piek, E. ; Sleumer, L.S.; Someren, E.P. van ; Heuver, L.; Haan, J.R. de ; Grijs, I. de; Gilissen, C.F.H.A. ; Hendriks, J.M.; van Ravestein-van Os, R.I.; Bauerschmidt, S.; Dechering, K.J. ; Zoelen, E.J.J. van et al. sine al.

2010, Article / Letter to editor (Bone, vol. 46, iss. 3, (2010), pp. 613-627)
Integrating gene expression and go classification for pca by preclustering

Haan, J.R. de ; Piek, E. ; Schaik, R.C. Van; Vlieg, J. de ; Bauerschmidt, S.; Buydens, L.M.C. ; Wehrens, H.R.M.J.

2010, Article / Letter to editor (BMC Bioinformatics, vol. 11, (2010), pp. 1-10, article 158)
Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism

Vaes, B.L.T. ; Lute, C.; Woning, S.P. van der ; Piek, E. ; Vermeer, J.; Blom, H.J. ; Mathers, J.C.; Muller, M.; Groot, L. de; Steegenga, W.T.

2010, Article / Letter to editor (Bone, vol. 46, iss. 2, (2010), pp. 514-523)
Erbb2 is a target for usp8-deiated deubquitination

Meijer, I.M.J.; Leeuwen, J.E.M. van

2010, Article / Letter to editor (Cellular Signalling, vol. 23, iss. 2, (2010), pp. 458-467)
Different roles of inositol 1,4,5-trisphosphate receptor subtypes in prostaglandin f-2 alpha-induced calcium oscillations and pacemaking activity of nrk fibroblasts

Almirza, W.H.M.; Peters, P.H.J.; Meerwijk, W.P.M. van; Zoelen, E.J.J. van ; Theuvenet, A.P.R.

2010, Article / Letter to editor (Cell Calcium, vol. 47, iss. 6, (2010), pp. 544-553)
Effects of the egfr inhibitor erlotinib on magnesium handling

Dimke, H.; Wijst, J.A.J. van der ; Alexander, T. ; Meijer, I.M.J.; Mulder, G.M.; Goor, H. van ; Tejpar, S.; Hoenderop, J.G.J. ; Bindels, R.J.

2010, Article / Letter to editor (Journal of the American Society of Nephrology, vol. 21, iss. 8, (2010), pp. 1309-1316)
Growth-dependent modulation of capacitative calcium entry in normal rat kidney fibroblasts

Dernison, M.M. ; Almirza, W.H.M.A.; Kusters, J.M.A.M. ; Meerwijk, W.P.M. van; Gielen, C.C.A.M. ; Zoelen, E.J.J. van ; Theuvenet, A.P.R.

2010, Article / Letter to editor (Cellular Signalling, vol. 22, iss. 7, (2010), pp. 1044-1053)
Cell death or survival promoted by alternative isoforms of erbb4

Sundvall, M.; Veikkolainen, V.; Kurppa, K.; Salah, Z.; Tvorogov, D.; Zoelen, Joop van ; Aqeilan, R.; Elenius, K.

2010, Article / Letter to editor (Molecular Biology of the Cell, vol. 21, iss. 23, (2010), pp. 4275-4286)
Manipulating heat shock factor-1 in xenopus tadpoles: Neuronal tissues are refractory to exogenous expression

Dirks, R.P.H. ; Geel, R. van ; Hensen, S.M.M.; Genesen, S.T. van ; Lubsen, N.H.

2010, Article / Letter to editor (PLoS One, vol. 5, iss. 4, (2010), article e10158)
Co-chaperones are limiting in a depleted chaperone network

Heldens, L. ; Dirks, R.P.H. ; Hensen, S.M.M.; Onnekink, C.; Genesen, S.T. van ; Rustenburg, F.; Lubsen, N.H.

2010, Article / Letter to editor (Cellular and Molecular Life Sciences, vol. 67, iss. 23, (2010), pp. 4035-4048)
Explosive expansion of beta gamma-crystallin genes in the ancestral vertebrate (vol 71, 219, 2010)

Kappe, G. ; Purkiss, A.G.; Genesen, S.T. van ; Slingsby, C; Lubsen, N.H.

2010, Article / Letter to editor (Journal of Molecular Evolution, vol. 71, iss. 4, (2010), pp. 317-318)
Explosive expansion of beta gamma-crystallin genes in the ancestral vertebrate

Kappe, G. ; Purkiss, A.G.; Genesen, S.T. van ; Slingsby, C; Lubsen, N.H.

2010, Article / Letter to editor (Journal of Molecular Evolution, vol. 71, iss. 3, (2010), pp. 219-230)

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