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Nephrotoxicity of concomitant piperacillin/tazobactam and teicoplanin compared with monotherapy

Workum, J.D.; Kramers, C. ; Kolwijck, E. ; Schouten, J.A. ; Wildt, S.N. de ; Brüggemann, R.J.M.

2021, Article / Letter to editor (Journal of Antimicrobial Chemotherapy, vol. 76, iss. 1, (2021), pp. 212-219)
Pharmacological and Parenteral Nutrition-Based Interventions in Microvillus Inclusion Disease

Leng, C.; Rings, E.; Wildt, S.N. de ; Ijzendoorn, S.C. van

2021, Article / Letter to editor (Journal of Clinical Medicine, vol. 10, iss. 1, (2021), article 22)
External Validation of Model-Based Dosing Guidelines for Vancomycin, Gentamicin, and Tobramycin in Critically Ill Neonates and Children: A Pragmatic Two-Center Study

Hartman, S.J.F. ; Orriens, L.B.; Zwaag, S.M.; Poel, T.; Hoop, M. de; Wildt, S.N. de

2020, Article / Letter to editor (Paediatric Drugs, vol. 22, iss. 4, (2020), pp. 433-444)
Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial

Bestebreurtje, P.; Koning, B.A.E. de; Roeleveld, N. ; Knibbe, C.A.J.; Tibboel, D.; Groen, B. van; Ven, C.P. van de; Plötz, F.B.; Wildt, S.N. de

2020, Article / Letter to editor (European Journal of Drug Metabolism and Pharmacokinetics, vol. 45, iss. 5, (2020), pp. 635-643)
Developmental patterns in human blood-brain barrier and blood-cerebrospinal fluid barrier ABC drug transporter expression

Verscheijden, L.F.M.; Hattem, A.C. van; Pertijs, J.C.L.M. ; Jongh, C.A. de; Verdijk, R.M.; Smeets, B. ; Koenderink, J.B. ; Russel, F.G.M. ; Wildt, S.N. de

2020, Article / Letter to editor (Histochemistry and Cell Biology, vol. 154, iss. 3, (2020), pp. 265-273)
Risk factors for intensive care admission in children with severe acute asthma in the Netherlands: a prospective multicentre study

Boeschoten, S.A.; Boehmer, A.L.M.; Merkus, P.J.F.M. ; Rosmalen, J. van; Jongste, J.C. de; Fraaij, P.L.; Molenkamp, R.; Heisterkamp, S.G.J.; Woensel, J.B. van; Kapitein, B.; Haarman, E.G.; Asperen, R.M. Wösten-van; Kneyber, M.C.J.; Lemson, J. ; Hartman, S.J.F. ; Waardenburg, D.A. van; Bunker-Wiersma, H.E.; Brouwer, C.N.M.; Ewijk, B.E. van; Landstra, A.M.; Verwaal, M.; Vaessen-Verberne, A.A.; Hammer, S.; Buysse, C.M.; Hoog, M. de et al. sine al.

2020, Article / Letter to editor (ERJ Open Research, vol. 6, iss. 3, (2020), article 00126-2020)
Completing the Enalaprilat Excretion Pathway-Renal Handling by the Proximal Tubule

Smeets, N.J.L. ; Litjens, C.H.C. ; Heuvel, J.M.W. van den ; Hove, H.; Broek, P.H.H. van den ; Russel, F.G.M. ; Koenderink, J.B. ; Wildt, S.N. de

2020, Article / Letter to editor (Pharmaceutics, vol. 12, iss. 10, (2020), article E935)
Considerations in Neuromuscular Blockade in the ICU: A Case Report and Review of the Literature

Workum, J.D.; Janssen, S.H.V.; Touw, H.R.W.

2020, Article / Letter to editor (Case reports in critical care, vol. 2020, (2020), article 8780979)
Gender and Authorship in Pediatric Critical Care Randomized Control Trials

Xu, G.M.; Zavalkoff, S.; Wildt, S.N. de ; Duffett, M.

2020, Article / Letter to editor (Pediatric Critical Care Medicine, vol. 21, iss. 12, (2020), pp. 1035-1041)
Ontogeny Related Changes in the Pediatric Liver Metabolome

Wilson, Christopher M.; Li, Qian; Gaedigk, R.; Bi, C.; Wildt, S.N. de ; Steven Leeder, J.; Fridley, B.

2020, Article / Letter to editor (Frontiers in Pediatrics, vol. 8, (2020), article 549)
Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus

Vet, N.J.; Winter, Brenda C.M. de; Koninckx, Muriel; Boeschoten, Shelley A.; Boehmer, Annemie L.M.; Verhallen, Jacintha T.; Wildt, S.N. de ; Koch, Birgit C.P.; Hoog, M. de

2020, Article / Letter to editor (Clinical Pharmacokinetics, vol. 59, iss. 2, (2020), pp. 257-264)
Involve Children and Parents in Clinical Studies

Vermeulen, E.; Karsenberg, K.; Lee, J.H. van der; Wildt, S.N. de

2020, Article / Letter to editor (Cts-Clinical and Translational Science, vol. 13, iss. 1, (2020), pp. 11-13)
Proof of Concept: First Pediatric [(14) C]microtracer Study to Create Metabolite Profiles of Midazolam

Groen, B.D.; Duijn, E. van; Vries, A. De; Mooij, M.G.; Tibboel, D.; Vaes, W.H.; Wildt, S.N. de

2020, Article / Letter to editor (Clinical Pharmacology and Therapeutics, vol. 108, iss. 5, (2020), pp. 1003-1009)
OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery

Matic, M.; Hoogd, Sjoerd de; Wildt, S.N. de ; Tibboel, D.; Knibbe, Catherijne A.J.; Schaik, R.H. van

2020, Article / Letter to editor (Pharmacogenomics, vol. 21, iss. 3, (2020), pp. 181-193)
Chloroquine Dosing Recommendations for Pediatric COVID-19 Supported by Modeling and Simulation

Verscheijden, L.F.M.; Zanden, T.M. van der; Bussel, L.P.M. van; Hoop-Sommen, M. de; Russel, F.G.M. ; Johnson, T.N.; Wildt, S.N. de

2020, Article / Letter to editor (Clinical Pharmacology and Therapeutics, vol. 108, iss. 2, (2020), pp. 248-252)
Development and Stability Study of an Omeprazole Suppository for Infants

Bestebreurtje, P.; Roeleveld, N. ; Knibbe, C.A.J.; Sorge, A.A. van; Plötz, F.B.; Wildt, S.N. de

2020, Article / Letter to editor (European Journal of Drug Metabolism and Pharmacokinetics, vol. 45, iss. 5, (2020), pp. 627-633)
A New Framework to Implement Model-Informed Dosing in Clinical Guidelines: Piperacillin and Amikacin as Proof of Concept

Hartman, S.J.F. ; Swaving, J.G.E.; Beek, S.W. van ; Groen, B.D.; Hoop, M. de; Zanden, T.M. van der; Heine, R. ter ; Wildt, S.N. de

2020, Article / Letter to editor (Frontiers in Pharmacology, vol. 11, (2020), article 592204)
Pharmacokinetics and Target Attainment of Antibiotics in Critically Ill Children: A Systematic Review of Current Literature.

Hartman, S.J.F. ; Bruggemann, R.J.M. ; Orriens, L.; Dia, N.; Schreuder, M.F. ; Wildt, S.N. de

2020, Article / Letter to editor (Clinical Pharmacokinetics, vol. 59, iss. 2, (2020), pp. 173-205)
Proenkephalin as a new biomarker for pediatric acute kidney injury - reference values and performance in children under one year of age

Hartman, S.J.F. ; Zwiers, Alexandra J.M.; Water, Nadies E.C. van de; Rosmalen, Joost van; Struck, Joachim; Schulte, Janin; Pickkers, P. ; Beunders, R. ; Schreuder, M.F. ; Wildt, S.N. de

2020, Article / Letter to editor (Clinical Chemistry and Laboratory Medicine, vol. 58, iss. 11, (2020), pp. 1911-1919)
Low Bioavailability of Oral Tacrolimus Suspension in Pediatric Kidney Transplant Patients

Schijvens, A.M. ; Wildt, S.N. de ; Cornelissen, E.A.M. ; Hesteren, F.H.S. van; Schreuder, M.F. ; Heine, R. ter

2020, Article / Letter to editor (Clinical Pharmacokinetics, vol. 59, iss. 11, (2020), pp. 1483-1485)
A continued method performance monitoring approach for the determination of pediatric renin samples - application within a European clinical trial

Feickert, M.; Burdman, I.; Makowski, N.; Ali, M; Wildt, S.N. de ; Bartel, A.; Burckhardt, B.B.

2020, Article / Letter to editor (Clinical Chemistry and Laboratory Medicine, vol. 58, iss. 11, (2020), pp. 1847-1855)
Development of implementation of a paediatric dosing calculator integrated in the Dutch Paediatric Formulary

Zanden, T.M. van der; Goedknegt, L.H., M. de; Mooij, M.G.; Wildt, S.N. de ; Sijs, I.H. van der

2020, Article / Letter to editor (Drugs & Therapy Perspectives, vol. 36, (2020), pp. 253-262)
Does a Dose Calculator as an Add-On to a Web-Based Paediatric Formulary Reduce Calculation Errors in Paediatric Dosing? A Non-Randomized Controlled Study

Zanden, T.M. van der; Hoog, M. de; Windster, J.D.; Rosmalen, J. van; Sijs, I.H. van der; Wildt, S.N. de

2020, Article / Letter to editor (Paediatric Drugs, vol. 22, iss. 2, (2020), pp. 229-239)
Diagnosis and Treatment of Chronic Neuropathic and Mixed Pain in Children and Adolescents: Results of a Survey Study amongst Practitioners

Leeuw, T.G. de; Zanden, Tjitske van Der; Ravera, Simona; Felisi, M.; Bonifazi, D.; Tibboel, D.; Kaguelidou, F.; Wildt, S.N. de

2020, Article / Letter to editor (Children, vol. 7, iss. 11, (2020), article 208)
A comprehensive quality control system suitable for academic research: application in a pediatric study

Makowski, N.; Ciplea, A.M.; Ali, M; Burdman, I.; Wildt, S.N. de ; Bartel, A.; Burckhardt, B.B.

2020, Article / Letter to editor (Bioanalysis, vol. 12, iss. 5, (2020), pp. 319-333)
Alternative Splicing of the SLCO1B1 Gene: An Exploratory Analysis of Isoform Diversity in Pediatric Liver

Groen, B.D.; Bi, C.; Gaedigk, R.; Staggs, V.S.; Tibboel, D.; Wildt, S.N. de ; Leeder, J.S.

2020, Article / Letter to editor (Cts-Clinical and Translational Science, vol. 13, iss. 3, (2020), pp. 509-519)
Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology

Schrier, L.; Hadjipanayis, A.; Stiris, T.; Ross-Russell, R.I.; Valiulis, A.; Turner, M.A.; Zhao, W.; Cock, P. De; Wildt, S.N. de ; Allegaert, K.; Anker, J. van den et al. sine al.

2020, Article / Letter to editor (European Journal of Pediatrics, vol. 179, iss. 5, (2020), pp. 839-847)
Pharmacokinetics in children with chronic kidney disease

Schijvens, A.M. ; Wildt, S.N. de ; Schreuder, M.F.

2020, Article / Letter to editor (Pediatric Nephrology, vol. 35, iss. 7, (2020), pp. 1153-1172)
Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Infliximab in Pediatric Inflammatory Bowel Disease: A Systematic Review and Revised Dosing Considerations

Winter, D.A.; Joosse, M.E.; Wildt, S.N. de ; Taminiau, J.; Ridder, L.; Escher, J.C.

2020, Article / Letter to editor (Journal of Pediatric Gastroenterology and Nutrition, vol. 70, iss. 6, (2020), pp. 763-776)
Physiologically-based pharmacokinetic models for children: Starting to reach maturation?

Verscheijden, L.F.M.; Koenderink, J.B. ; Johnson, T.N.; Wildt, S.N. de ; Russel, F.G.M.

2020, Article / Letter to editor (Pharmacology and Therapeutics. Part A: Chemotherapy, Toxicology and Metabolic Inhibitors, vol. 211, (2020), article 107541)
Fit-for-Purpose Quality Control System in Continuous Bioanalysis during Long-Term Pediatric Studies

Ali, M; Tins, J.; Wildt, S.N. de ; Burckhardt, B.B.

2020, Article / Letter to editor (Aaps Journal, vol. 22, iss. 2, (2020), article 37)
A quality control system for ligand-binding assay of plasma renin activity: Proof-of-concept within a pharmacodynamic study

Suessenbach, F.K.; Makowski, N.; Feickert, M.; Gangnus, T.; Wildt, S.N. de ; Tins, J.; Burckhardt, B.B.

2020, Article / Letter to editor (Journal of Pharmaceutical and Biomedical Analysis, vol. 181, (2020), article 113090)
Finger-Prick Blood Sampling for Therapeutic Drug Monitoring: Be Aware of Skin Contamination by Nebulized Drugs

Winter, B.C. de; Hoog, M. de; Vet, N.J.; Dunk-Craaijo, J.H.; Koch, B.C.; Wildt, S.N. de

2020, Article / Letter to editor (Therapeutic Drug Monitoring, vol. 42, iss. 3, (2020), pp. 512-513)
Impact of gastrointestinal physiology on drug absorption in special populations--An UNGAP review

Stillhart, C.; Vucicevic, K.; Augustijns, P.; Basit, A.W.; Batchelor, H.; Flanagan, T.R.; Gesquiere, I.; Greupink, R.; Keszthelyi, D.; Koskinen, M.; Madla, C.M.; Matthys, C.; Miljus, G.; Mooij, M.G.; Parrott, N.; Ungell, A.L.; Wildt, S.N. de ; Orlu, M.; Klein, S.; Mullertz, A. et al. sine al.

2020, Article / Letter to editor (European Journal of Pharmaceutical Sciences, vol. 147, (2020), article 105280)
Dose-linearity of the pharmacokinetics of an intravenous [(14) C]midazolam microdose in children

Groen, B.D.; Vaes, W.H.; Park, B.K.; Krekels, E.H.J.; Duijn, E. van; Korgvee, L.T.; Maruszak, W.; Grynkiewicz, G.; Garner, R.C.; Knibbe, Catherijne A.J.; Tibboel, D.; Wildt, S.N. de ; Turner, M.A. et al. sine al.

2019, Article / Letter to editor (British Journal of Clinical Pharmacology, vol. 85, iss. 10, (2019), pp. 2332-2340)
A Comprehensive Analysis of Ontogeny of Renal Drug Transporters: mRNA Analyses, Quantitative Proteomics, and Localization

Cheung, K.W.K.; Groen, B.D.; Spaans, E.; Borselen, M.D. van; Bruijn, A. de; Simons-Oosterhuis, Y.; Tibboel, D.; Samsom, J.N.; Verdijk, R.M.; Smeets, B. ; Zhang, L.; Huang, S.M.; Giacomini, K.M.; Wildt, S.N. de et al. sine al.

2019, Article / Letter to editor (Clinical Pharmacology and Therapeutics, vol. 106, iss. 5, (2019), pp. 1083-1092)
The KHENERGY Study: Safety and Efficacy of KH176 in Mitochondrial m.3243A>G Spectrum Disorders

Janssen, M.C.H. ; Koene, S. ; Laat, P. de ; Hemelaar, P. ; Pickkers, P. ; Spaans, Edwin; Beukema, R.J. ; Beyrath, J.D. ; Groothuis, J.T. ; Verhaak, C.M. ; Smeitink, J. et al. sine al.

2019, Article / Letter to editor (Clinical Pharmacology and Therapeutics, vol. 105, iss. 1, (2019), pp. 101-111)
The potential impact of hematocrit correction on evaluation of tacrolimus target exposure in pediatric kidney transplant patients

Schijvens, A.M. ; Hesteren, Fransje H.S. van; Cornelissen, E.A.M. ; Bootsma-Robroeks, Charlotte M.H.H.T.; Bruggemann, R.J.M. ; Burger, D.M. ; Wildt, S.N. de ; Schreuder, M.F. ; Heine, R. ter

2019, Article / Letter to editor (Pediatric Nephrology, vol. 34, iss. 3, (2019), pp. 507-515)
Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome

Schijvens, A.M. ; Heine, R. ter ; Wildt, S.N. de ; Schreuder, M.F.

2019, Article / Letter to editor (Pediatric Nephrology, vol. 34, iss. 3, (2019), pp. 389-403)
Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation A Randomized Clinical Trial

Onland, Wes; Cools, Filip; Kroon, Andre; Rademaker, Karin; Merkus, Maruschka P.; Dijk, Peter H.; Heijst, A.F.J. van ; Matthijsse, R. ; Boode, W.P. de ; Baal, Caroline van; Wildt, S.N. de et al. sine al.

2019, Article / Letter to editor (Jama : Journal of the American Medical Association, vol. 321, iss. 4, (2019), pp. 354-363)
Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

Cheung, Kit Wun Kathy; Groen, Bianca D. van; Burckart, Gilbert J.; Zhang, L.; Wildt, S.N. de ; Huang, Shiew-Mei

2019, Article / Letter to editor (Journal of Clinical Pharmacology and Journal of New Drugs, vol. 59, (2019), pp. S56-S69)
Pharmacotherapy in paediatric heart failure: a Delphi process

Diez, Cristina C.; Khalil, F.; Makowski, N.; Schwender, Holger; Jovanovic, I.; Dalinghaus, M.; Wildt, S.N. de ; Laeer, S.

2019, Article / Letter to editor (Cardiology in the Young, vol. 29, iss. 7, (2019), pp. 869-876, article PII S104795111900066)
Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model

Voller, Swantje; Flint, R.B. ; Beggah, Fouzi; Reiss, Irwin K.M.; Andriessen, Peter; Zimmermann, L.J.; Liem, K.D. ; Wildt, S.N. de ; Knibbe, Catherijne A.J.; Simons, Sinno H.P.

2019, Article / Letter to editor (Journal of Clinical Pharmacology and Journal of New Drugs, vol. 59, iss. 10, (2019), pp. 1300-1308)
Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

Verscheijden, L.F.M.; Koenderink, J.B. ; Wildt, S.N. de ; Russel, F.G.M.

2019, Article / Letter to editor (Plos Computational Biology, vol. 15, iss. 6, (2019), pp. e1007117)
Orodispersible minitablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety study

Bajcetic, M.; Wildt, S.N. de ; Dalinghaus, M.; Breitkreutz, J.; Klingmann, I.; Lagler, F.B.; Keatley-Clarke, A.; Breur, J.M.; Male, C.; Jovanovic, I.; Szatmari, A.; Ablonczy, L.; Burckhardt, B.B.; Cawello, W.; Kleine, K.; Obarcanin, E.; Spatenkova, L.; Swoboda, V.; Meulen, M. van der; Wagner, P.; Walsh, J.; Laer, S. et al. sine al.

2019, Article / Letter to editor (Contemporary Clinical Trials Communications, vol. 15, (2019), pp. 100393)
A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates in Children

Brussee, J.M.; Krekels, E.H.J.; Calvier, E.A.M.; Palic, S.; Rostami-Hodjegan, A.; Danhof, M.; Barrett, J.S.; Wildt, S.N. de ; Knibbe, C.A.

2019, Article / Letter to editor (Aaps Journal, vol. 21, iss. 5, (2019), pp. 81)
beta-Blockade attenuates renal blood flow in experimental endotoxic shock by reducing perfusion pressure

Loon, L.M. van; Rongen, G.A.P.J.M. ; Hoeven, J.G. van der ; Veltink, P.H.; Lemson, J.

2019, Article / Letter to editor (Physiological Reports, vol. 7, iss. 23, (2019), pp. e14301)
Enteral Acetaminophen Bioavailability in Pediatric Intensive Care Patients Determined With an Oral Microtracer and Pharmacokinetic Modeling to Optimize Dosing

Kleiber, N.; Calvier, E.; Mooij, M.G.; Krekels, E.H.J.; Vaes, W.H.; Tibboel, D.; Knibbe, C.A.J.; Wildt, S.N. de

2019, Article / Letter to editor (Critical Care Medicine, vol. 47, iss. 12, (2019), pp. e975-e983)
Target attainment of cefotaxime in critically ill children with meningococcal septic shock as a model for cefotaxime dosing in severe pediatric sepsis

Hartman, S.J.F. ; Boeddha, Navin P.; Ekinci, Ebru; Koch, Birgit C.P.; Donders, R. ; Hazelzet, Jan A.; Driessen, Gertjan J.; Wildt, S.N. de

2019, Article / Letter to editor (European Journal of Clinical Microbiology and Infectious Diseases, vol. 38, iss. 7, (2019), pp. 1255-1260)
Combining Brain Microdialysis and Translational Pharmacokinetic Modeling to Predict Drug Concentrations in Pediatric Severe Traumatic Brain Injury: The Next Step Toward Evidence-Based Pharmacotherapy?

Ketharanathan, N.; Yamamoto, Y.; Rohlwink, U.K.; Wildschut, E.D.; Mathot, R.A.A.; Lange, E.C.M. de; Wildt, S.N. de ; Argent, A.C.; Tibboel, D.; Figaji, A.A.

2019, Article / Letter to editor (Journal of Neurotrauma, vol. 36, iss. 1, (2019), pp. 111-117)

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