Browsing by Author "Dinarello, C.A."

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Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity
Mantovani, A.; Dinarello, C.A. ; Molgora, M.; Garlanda, C.
2019, Article / Letter to editor (Immunity, vol. 50, iss. 4, (2019), pp. 778-795)
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease
Hojen, J.F.; Kristensen, Marie Louise Vindvad; McKee, Amy S.; Wade, Megan Taylor; Azam, T.; Lunding, Lars P.; Graaf, D.M. de; Fischer, S.; Dinarello, C.A.
2019, Article / Letter to editor (Nature Immunology, vol. 20, iss. 9, (2019), pp. 1138-+)
The IL-1 family of cytokines and receptors in rheumatic diseases
Dinarello, C.A.
2019, Article / Letter to editor (Nature Reviews. Rheumatology, vol. 15, iss. 10, (2019), pp. 612-632)
The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis
Madonna, S.; Girolomoni, G.; Dinarello, C.A. ; Albanesi, C.
2019, Article / Letter to editor (International Journal of Molecular Sciences, vol. 20, iss. 13, (2019), article 3318)
OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis
Sanchez-Fernandez, Alba; Skouras, Damaris B.; Dinarello, C.A. ; Lopez-Vales, R.
2019, Article / Letter to editor (Frontiers in Immunology, vol. 10, (2019), article 2578)
Blocking IL-1 beta reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation
Kaplanov, Irena; Carmi, Yaron; Kornetsky, Rachel; Shemesh, Avishai; Shurin, Galina V.; Shurin, Michael R.; Dinarello, C.A. ; Voronov, E.; Apte, R.N.
2019, Article / Letter to editor (Proceedings of the National Academy of Sciences USA, vol. 116, iss. 4, (2019), pp. 1361-1369)
Interleukin-37 monomer is the active form for reducing innate immunity
Eisenmesser, E.Z.; Gottschlich, Adrian; Redzic, Jasmina S.; Paukovich, Natasia; Nix, Jay C.; Azam, T.; Meng, Xianzhong; Dinarello, C.A.
2019, Article / Letter to editor (Proceedings of the National Academy of Sciences USA, vol. 116, iss. 12, (2019), pp. 5514-5522)
Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease
Cavalli, G.C.; Tomelleri, A.; Luca, G. De; Campochiaro, C.; Dinarello, C.A. ; Baldissera, E.; Dagna, L.
2019, Article / Letter to editor (Arthritis Research & Therapy, vol. 21, iss. 1, (2019), pp. 54)
Role for nuclear interleukin-37 in the suppression of innate immunity
Li, Suzhao; Amo-Aparicio, Jesus; Neff, C.P.; Tengesdal, I.W.; Azam, T.; Palmer, B.E.; Bufler, P.; Dinarello, C.A.
2019, Article / Letter to editor (Proceedings of the National Academy of Sciences USA, vol. 116, iss. 10, (2019), pp. 4456-4461)
Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression
Cleophas, M.C.P.; Crisan, T. O.; Kluck, V.; Hoogerbrugge, N. ; Netea-Maier, R.T. ; Dinarello, C.A. ; Netea, M.G. ; Joosten, L.A.B.
2019, Article / Letter to editor (Arthritis Research & Therapy, vol. 21, (2019), article 50)
Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits &ITEx Vivo&IT Lipopolysaccharide-Induced Inflammatory Responses
Brinkmann, C.R.; Hojen, J.F.; Rasmussen, T.A.; Kjaer, A.; Olesen, R.; Denton, Paul W.; Dinarello, C.A. ; Tolstrup, M.
2018, Article / Letter to editor (Msphere, vol. 3, iss. 1, (2018), article e00616-17)
NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis
Marchetti, C.; Swartzwelter, Benjamin; Koenders, M.I. ; Azam, T.; Tengesdal, I.W.; Powers, Nick; Graaf, D.M. de; Dinarello, C.A. ; Joosten, L.A.B.
2018, Article / Letter to editor (Arthritis Research & Therapy, vol. 20, (2018), article 169)
IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
Mercurio, Laura; Morelli, M.; Scarponi, Claudia; Eisenmesser, E.Z.; Doti, Nunzianna; Pagnanelli, Gianluca; Dinarello, C.A. ; Albanesi, Cristina; Madonna, Stefania
2018, Article / Letter to editor (Cell Death and Disease, vol. 9, (2018), article 1104)
IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake
Kuipers, E.N.; Dam, A.D. van; Ballak, D.B.; Wit, E.A. de; Dinarello, C.A. ; Stienstra, R. ; Diepen, J.A. van; Rensen, P.C.; Boon, M.R.
2018, Article / Letter to editor (International Journal of Molecular Sciences, vol. 19, iss. 8, (2018), article 2264)
Human Interleukin-32 gamma Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice
Gomes, R.S.; Teodoro Silva, Muriel Vilela; Dos Santos, J.C.; Linge, Christine van; Reis, Juliana Machado; Teixeira, M.M.; Dinarello, C.A. ; Joosten, L.A.B. ; Ribeiro-Dias, F.
2018, Article / Letter to editor (Infection and Immunity, vol. 86, iss. 5, (2018), article e00796-17)
Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity
Dinarello, C.A.
2018, Article / Letter to editor (Immunological Reviews, vol. 281, iss. 1, (2018), pp. 5-7)
Overview of the IL-1 family in innate inflammation and acquired immunity
Dinarello, C.A.
2018, Article / Letter to editor (Immunological Reviews, vol. 281, iss. 1, (2018), pp. 8-27)
Indeed, IL-18 is more than an inducer of IFN-gamma
Dinarello, C.A. ; Kaplanski, G.
2018, Article / Letter to editor (Journal of Leukocyte Biology, vol. 104, iss. 2, (2018), pp. 237-238)
An Interleukin-1 Signature in Breast Cancer Treated with Interleukin-1 Receptor Blockade: Implications for Treating Cytokine Release Syndrome of Checkpoint Inhibitors
Dinarello, C.A.
2018, Article / Letter to editor (Cancer Research, vol. 78, iss. 18, (2018), pp. 5200-5202)
Suppression of inflammation and acquired immunity by IL-37
Cavalli, G.; Dinarello, C.A.
2018, Article / Letter to editor (Immunological Reviews, vol. 281, iss. 1, (2018), pp. 179-190)
The selective ROCK2 inhibitor KD025 reduces IL-17 secretion in human peripheral blood mononuclear cells independent of IL-1 and IL-6
Tengesdal, I.W.; Kitzenberg, D.; Li, S.; Nyuydzefe, M.S.; Weiss, J.M.; Zhang, J.; Waksal, S.D.; Zanin-Zhorov, A.; Dinarello, C.A.
2018, Article / Letter to editor (European Journal of Immunology, vol. 48, iss. 10, (2018), pp. 1679-1686)
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism
Jeong, Mark Y.; Lin, Ying H.; Wennersten, Sara A.; Demos-Davies, Kimberly M.; Cavasin, Maria A.; Mahaffey, Jennifer H.; Dinarello, C.A. ; McKinsey, T.A.
2018, Article / Letter to editor (Science Translational Medicine, vol. 10, iss. 427, (2018), article eaao0144)
The Inter-Relationship of Platelets with Interleukin-1 beta-Mediated Inflammation in Humans
Tunjungputri, R.N.; Li, Yang; Groot, P.G. de; Dinarello, C.A. ; Smeekens, S.P.; Jaeger, M.; Doppenberg-Oosting, M. ; Lemmers, H.L.M. ; Kumar, V.; Joosten, L.A.B. ; Netea, M.G. ; Ven, A.J.A.M. van der ; Mast, Q. de et al. sine al.
2018, Article / Letter to editor (Thrombosis and Haemostasis, vol. 118, iss. 12, (2018), pp. 2112-2125)
Interleukin-1alpha as an intracellular alarmin in cancer biology
Voronov, E.; Dinarello, C.A. ; Apte, R.N.
2018, Article / Letter to editor (Seminars in Immunology, vol. 38, (2018), pp. 3-14)
Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes
Damen, M.S.M.A.; Dos Santos, J.C.; Hermsen, R. ; van der Vliet, J.A. ; Netea, M.G. ; Riksen, N.P. ; Dinarello, C.A. ; Joosten, L.A.B. ; Heinhuis, B.
2018, Article / Letter to editor (Atherosclerosis, vol. 271, (2018), pp. 193-202)
Role of glutathione metabolism in host defense against Borrelia burgdorferi infection
Kerstholt, M; Vrijmoeth, H.D.; Lachmandas, E.L.; Oosting, M. ; Lupse, M.; Flonta, M.; Dinarello, C.A. ; Netea, M.G. ; Joosten, L.A.B.
2018, Article / Letter to editor (Proceedings of the National Academy of Sciences USA, vol. 115, iss. 10, (2018), pp. E2320-E2328)
OLT1177, a beta-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
Marchetti, C.; Swartzwelter, Benjamin; Gamboni, Fabia; Neff, C.P.; Richter, Katrin; Azam, T.; Joosten, L.A.B. ; Dinarello, C.A.
2018, Article / Letter to editor (vol. 115, iss. 7, (2018), pp. E1530-E1539)
Anakinra Therapy for Non-cancer Inflammatory Diseases
Cavalli, G.; Dinarello, C.A.
2018, Article / Letter to editor (Frontiers in Pharmacology, vol. 9, (2018), article 1157)
Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue
Ballak, D.B.; Li, Suzhao; Cavalli, G.; Stahl, J.; Tengesdal, Isak W.; Diepen, Janna A. van; Kluck, Viola; Tack, C.J.J. ; Stienstra, R. ; Seals, D.R.; Dinarello, C.A. et al. sine al.
2018, Article / Letter to editor (Journal of Biological Chemistry, vol. 293, iss. 37, (2018), pp. 14224-14236)
Interleukin-1 as a mediator of fatigue in disease: a narrative review
Roerink, M.E.; Schaaf, M.E. van der; Dinarello, C.A. ; Knoop, H. ; Meer, J.W.M. van der
2017, Article / Letter to editor (Journal of Neuroinflammation, vol. 14, iss. 1, (2017), pp. 16)
Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection
Davis, C.J.; Zielinski, M.R.; Dunbrasky, D.; Taishi, P.; Dinarello, C.A. ; Krueger, J.M.
2017, Article / Letter to editor (Neurobiology of Sleep and Circadian Rhythms, vol. 3, (2017), pp. 1-9)
Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT
Choi, S.W.; Braun, T.; Henig, I.; Gatza, E.; Magenau, J.; Parkin, B.; Pawarode, A.; Riwes, M.; Yanik, G.; Dinarello, C.A. ; Reddy, P. et al. sine al.
2017, Article / Letter to editor (Blood, vol. 130, iss. 15, (2017), pp. 1760-1767)
Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice
Li, Jilin; Zhai, Y.; Ao, L.; Hui, H.; Fullerton, D.A.; Dinarello, C.A. ; Meng, X.
2017, Article / Letter to editor (Cytokine, vol. 95, (2017), pp. 55-63)
IL-32gamma promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis
Gomes, R.S.; Silva, M.V.T.; Santos, J.C. Dos; Silva, L.L. de Lima; Batista, A.C.; Machado, J.R.; Teixeira, M.M.; Dorta, M.L.; Oliveira, M.A. de; Dinarello, C.A. ; Joosten, L.A.B. ; Ribeiro-Dias, F. et al. sine al.
2017, Article / Letter to editor (Parasites & Vectors, vol. 10, iss. 1, (2017), pp. 336)
The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice
Hoeke, G.; Khedoe, P.; Diepen, J.A. van; Pike-Overzet, K.; Ven, B. van de; Vazirpanah, N.; Mol, I.; Hiemstra, P.S.; Staal, F.J.; Stienstra, R. ; Netea, M.G. ; Dinarello, C.A. ; Rensen, P.C.; Berbee, J.F. et al. sine al.
2017, Article / Letter to editor (International Journal of Molecular Sciences, vol. 18, iss. 8, (2017), article 1672)
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
Davegardh, C.; Broholm, C.; Perfilyev, A.; Henriksen, T.; Garcia-Calzon, S.; Peijs, L.; Hansen, N.S.; Volkov, P.; Kjobsted, R.; Wojtaszewski, J.F.; Pedersen, M.; Pedersen, B.K.; Ballak, D.B.; Dinarello, C.A. ; Heinhuis, B. ; Joosten, L.A.B. ; Nilsson, E.; Vaag, A.; Scheele, C.; Ling, C. et al. sine al.
2017, Article / Letter to editor (BMC Medicine, vol. 15, iss. 1, (2017), pp. 39)
Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species
Santos, J.C. Dos; Heinhuis, B. ; Gomes, R.S.; Damen, M.S.M.A.; Real, F.; Mortara, R.A.; Keating, S.T.; Dinarello, C.A. ; Joosten, L.A.B. ; Ribeiro-Dias, F.
2017, Article / Letter to editor (Plos Neglected Tropical Diseases, vol. 11, iss. 2, (2017), pp. e0005413)
A guiding map for inflammation
Netea, M.G. ; Balkwill, F.; Chonchol, M.; Cominelli, F.; Donath, M.Y.; Giamarellos-Bourboulis, E.J.; Golenbock, D.; Gresnigt, M.S.; Heneka, M.T.; Hoffman, H.M.; Hotchkiss, R.; Joosten, L.A.B. ; Kastner, D.L.; Korte, M.; Latz, E.; Libby, P.; Mandrup-Poulsen, T.; Mantovani, A.; Mills, K.H.; Nowak, K.L.; O'Neill, L.A.; Pickkers, P. ; Poll, T. van der; Ridker, P.M.; Schalkwijk, J. ; Schwartz, D.A.; Siegmund, B.; Steer, C.J.; Tilg, H.; Meer, J.W.M. van der ; Veerdonk, F.L. van de ; Dinarello, C.A. et al. sine al.
2017, Article / Letter to editor (Nature Immunology, vol. 18, iss. 8, (2017), pp. 826-831)
IL-18 binding protein reverses the life-threatening hyperinflammation of a baby with the NLRC4 mutation
Novick, D.; Dinarello, C.A.
2017, Article / Letter to editor (Journal of Allergy and Clinical Immunology, vol. 140, iss. 1, (2017), pp. 316)
IL-1 Inhibition and Vascular Function in CKD
Nowak, K.L.; Chonchol, M.; Ikizler, T.A.; Farmer-Bailey, H.; Salas, N.; Chaudhry, R.; Wang, W.; Smits, G.; Tengesdal, I.; Dinarello, C.A. ; Hung, A.M. et al. sine al.
2017, Article / Letter to editor (Journal of the American Society of Nephrology, vol. 28, iss. 3, (2017), pp. 971-980)
NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma
Zhai, Z.; Liu, W; Kaur, M.; Luo, Y.; Domenico, J.; Samson, J.M.; Shellman, Y.G.; Norris, D.A.; Dinarello, C.A. ; Spritz, R.A.; Fujita, M. et al. sine al.
2017, Article / Letter to editor (Oncogene, vol. 36, iss. 27, (2017), pp. 3820-3830)
Alarmins: Feel the Stress
Rider, P.; Voronov, E.; Dinarello, C.A. ; Apte, R.N.; Cohen, I.
2017, Article / Letter to editor (Journal of Immunology, vol. 198, iss. 4, (2017), pp. 1395-1402)
IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia
Schauer, A.E.; Klassert, T.E.; Lachner, C. von; Riebold, D.; Schneeweiss, A.; Stock, M.; Muller, M.M.; Hammerschmidt, S.; Bufler, P.; Seifert, U.; Dietert, K.; Dinarello, C.A. ; Nold, M.F.; Gruber, A.D.; Nold-Petry, C.A.; Slevogt, H. et al. sine al.
2017, Article / Letter to editor (Journal of Innate Immunity, vol. 9, iss. 4, (2017), pp. 403-418)
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
Neudecker, V.; Haneklaus, M.; Jensen, O.; Khailova, L.; Masterson, J.C.; Tye, H.; Biette, K.; Jedlicka, P.; Brodsky, K.S.; Gerich, M.E.; Mack, M.; Robertson, A.A.B.; Cooper, M.A.; Furuta, G.T.; Dinarello, C.A. ; O'Neill, L.A.; Eltzschig, H.K.; Masters, S.L.; McNamee, E.N. et al. sine al.
2017, Article / Letter to editor (Journal of Experimental Medicine, vol. 214, iss. 6, (2017), pp. 1737-1752)
Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial
Roerink, M.E.; Bredie, S.J.H. ; Heijnen, M.; Dinarello, C.A. ; Knoop, H. ; Meer, J.W.M. van der
2017, Article / Letter to editor (Annals of Internal Medicine C.2, vol. 166, iss. 8, (2017), pp. 557-564)
Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases
Damen, M.S.M.A.; Popa, C. ; Netea, M.G. ; Dinarello, C.A. ; Joosten, L.A.B.
2017, Article / Letter to editor (Atherosclerosis, vol. 264, (2017), pp. 83-91)
Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury
Maicas Blasco, N. ; Vlag, J. van der ; Bublitz, J.; Florquin, S.; Bakker-van Bebber, M.A.H. ; Dinarello, C.A. ; Verweij, V.G. ; Masereeuw, R. ; Joosten, L.A.B. ; Hilbrands, L.B.
2017, Article / Letter to editor (PLoS One, vol. 12, iss. 2, (2017), article e0168981)
Implication of the intestinal microbiome as a potential surrogate marker of immune responsiveness to experimental therapies in autoimmune diabetes
Needell, J.C.; Dinarello, C.A. ; Ir, D.; Robertson, C.E.; Ryan, S.M.; Kroehl, M.E.; Frank, D.N.; Zipris, D.
2017, Article / Letter to editor (PLoS One, vol. 12, iss. 3, (2017), article e0173968)
IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis
Damen, M.S.M.A.; Agca, R.; Holewijn, S.; Graaf, J. de ; Santos, J.C. Dos; Riel, P.L.C.M. van ; Fransen, J. ; Coenen, M.J.H. ; Nurmohamed, M.T.; Netea, M.G. ; Dinarello, C.A. ; Joosten, L.A.B. ; Heinhuis, B. ; Popa, C. et al. sine al.
2017, Article / Letter to editor (Scientific Reports, vol. 7, (2017), article 41629)
Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure
Cavalli, G.; Foppoli, M.; Cabrini, L.; Dinarello, C.A. ; Tresoldi, M.; Dagna, L.
2017, Article / Letter to editor (Frontiers in Immunology, vol. 8, (2017), article 131)

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