Browsing by Author "Kar, N.C.A.J. van de"

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The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment
Heuvel, L.P. van den ; Kar, N.C.A.J. van de ; Duineveld, C. ; Sarlea, A.; Velden, T.J.A.M. van der ; Liebrand, W.T.B.; Kraaij, S.A.W. van ; Schjalm, C.; Bouwmeester, R.N. ; Wetzels, J.F.M. ; Mollnes, T.E.; Volokhina, E.B. et al. sine al.
2020, Article / Letter to editor (Cellular & Molecular Immunology, vol. 17, (2020), pp. 653-655)
Preparing for a kidney transplant: Medical nephrectomy in children with nephrotic syndrome
Vos, Eefke; Koster-Kamphuis, L. ; Kar, N.C.A.J. van de ; Bootsma-Robroeks, C.M.H.H.T.; Cornelissen, E.A.M. ; Schreuder, M.F.
2020, Article / Letter to editor (Pediatric Transplantation, vol. 24, iss. 4, (2020), article e13703)
Shiga Toxin Selectively Upregulates Expression of Syndecan-4 and Adhesion Molecule ICAM-1 in Human Glomerular Microvascular Endothelium
Volokhina, E.B. ; Feitz, W.J.C. ; Elders, Lonneke M.; Velden, T.J.A.M. van der ; Kar, N.C.A.J. van de ; Heuvel, B. van den
2020, Article / Letter to editor (Toxins, vol. 12, iss. 7, (2020), article 435)
Primary Human Derived Blood Outgrowth Endothelial Cells: An Appropriate In Vitro Model to Study Shiga Toxin Mediated Damage of Endothelial Cells
Feitz, W.J.C. ; Kar, N.C.A.J. van de ; Cheong, I.; Velden, T.J.A.M. van der ; Ortiz-Sandoval, C.G.; Orth-Höller, D.; Heuvel, L.P.W.J. van den ; Licht, C.
2020, Article / Letter to editor (Toxins, vol. 12, iss. 8, (2020), article 483)
Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b
Bos, Ramon M. van den; Pearce, Nicholas M.; Granneman, Joke; Brondijk, T.Harma C.; Gros, P.; Berger, S.; Heuvel, L.P.W.J. van den ; Kar, N.C. van de ; Vries, A. de
2019, Article / Letter to editor (Frontiers in Immunology, vol. 10, (2019), article 2097)
Novel Assays to Distinguish Between Properdin-Dependent and Properdin-Independent C3 Nephritic Factors Provide Insight Into Properdin-Inhibiting Therapy
Michels, M.A.H.M. ; Kar, N.C.A.J. van de ; Bos, Ramon M. van den; Velden, T.J.A.M. van der ; Kraaij, S.A.W. van ; Sarlea, Sebastian A.; Volokhina, E.B. ; Heuvel, L.P.W.J. van den
2019, Article / Letter to editor (Frontiers in Immunology, vol. 10, (2019), article 1350)
Placental passage of eculizumab and complement blockade in a newborn
Duineveld, C. ; Wijnsma, K.L. ; Volokhina, E.B. ; Heuvel, L.P.W.J. van den ; Kar, N.C.A.J. van de ; Wetzels, J.F.M.
2019, Article / Letter to editor (Kidney International, vol. 95, iss. 4, (2019), pp. 996)
Eculizumab in atypical hemolytic uremic syndrome: strategies toward restrictive use
Wijnsma, K.L. ; Duineveld, C. ; Wetzels, J.F.M. ; Kar, N.C. van de
2019, Article / Letter to editor (Pediatric Nephrology, vol. 34, iss. 4, (2019), pp. 741-742)
Validity of the Patient Experiences and Satisfaction with Medications (PESaM) Questionnaire
Kimman, Merel L.; Wijsenbeek, Marlies S.; Kuijk, Sander M.J. van; Wijnsma, K.L. ; Kar, N.C.A.J. van de ; Storm, Marjolein; Wegman, Ingrid M.H.; Wetzels, J.
2019, Article / Letter to editor (Patient-Patient Centered Outcomes Research, vol. 12, iss. 1, (2019), pp. 149-162)
Glyco-iELISA: a highly sensitive and unambiguous serological method to diagnose STEC-HUS caused by serotype O157
Wijnsma, K.L. ; Veissi, S.T. ; Bommel, S.A. van; Heuver, Rik; Volokhina, E.B. ; Comerci, Diego J.; Kar, N.C.A.J. van de ; Heuvel, L.P.W.J. van den
2019, Article / Letter to editor (Pediatric Nephrology, vol. 34, iss. 4, (2019), pp. 631-639)
The role of properdin in complement-mediated renal diseases: a new player in complement-inhibiting therapy?
Michels, M.A.H.M. ; Volokhina, E.B. ; Kar, N.C.A.J. van de ; Heuvel, L.P.W.J. van den
2019, Article / Letter to editor (Pediatric Nephrology, vol. 34, iss. 8, (2019), pp. 1349-1367)
Pharmacology, Pharmacokinetics and Pharmacodynamics of Eculizumab, and Possibilities for an Individualized Approach to Eculizumab
Wijnsma, K.L. ; Heine, R. ter ; Moes, D.; Langemeijer, S.M. ; Schols, S.E.M. ; Volokhina, E.B. ; Heuvel, L.P.W.J. van den ; Wetzels, J.F.M. ; Kar, N.C.A.J. van de ; Bruggemann, R.J.
2019, Article / Letter to editor (Clinical Pharmacokinetics, vol. 58, iss. 7, (2019), pp. 859-874)
Clinical and genetic analyses of a Dutch cohort of 40 patients with a nephronophthisis-related ciliopathy
Stokman, M.F.; Zwaag, B. van der; Kar, N.C.A.J. van de ; Haelst, M.M. van; Eerde, A.M. van; Heijden, J.W. van der; Kroes, H.Y.; Ippel, E.; Schulp, A.J.A.; Gassen, K.L.I. van; Rooij, I.A.L.M. van ; Giles, R.H.; Beales, P.L.; Roepman, R. ; Arts, H.H. ; Bongers, E.M.H.F. ; Renkema, K.Y.; Knoers, N.; Reeuwijk, J. van ; Lilien, M.R. et al. sine al.
2018, Article / Letter to editor (Pediatric Nephrology, vol. 33, iss. 10, (2018), pp. 1701-1712)
Overactivity of alternative Pathway convertases in Patients With complement-Mediated renal Diseases
Michels, M.A.H.M. ; Kar, N.C.A.J. van de ; Okroj, M.; Blom, A.M.; Kraaij, S.A.W. van ; Volokhina, E.B. ; Heuvel, L.P.W.J. van den
2018, Article / Letter to editor (Frontiers in Immunology, vol. 9, (2018), article 612)
Genotype-phenotype correlations of low-frequency variants in the complement system in renal disease and age-related macular degeneration
Geerlings, M.J. ; Volokhina, E.B. ; Jong, E.K. de ; Kar, N.C. van de ; Pauper, M.; Hoyng, C.B. ; Heuvel, L.P. van den ; Hollander, A.I. den
2018, Article / Letter to editor (Clinical Genetics, vol. 94, iss. 3-4, (2018), pp. 330-338)
Safety and effectiveness of restrictive eculizumab treatment in atypical haemolytic uremic syndrome
Wijnsma, K.L. ; Duineveld, C. ; Volokhina, E.B. ; Heuvel, L.P.W.J. van den ; Kar, N.C.A.J. van de ; Wetzels, J.F.M.
2018, Article / Letter to editor (Nephrology, Dialysis, Transplantation, vol. 33, iss. 4, (2018), pp. 635-645)
Genetic predisposition to infection in a case of atypical hemolytic uremic syndrome
Heuvel, L.P. van den ; Riesbeck, Kristian; Tahir, Omaima El; Gracchi, V.; Kremlitzka, Mariann; Morre, Servaas A.; Kar, N.C. van de ; Blom, A.M.; Volokhina, E.B.
2018, Article / Letter to editor (Journal of Human Genetics, vol. 63, iss. 1, (2018), pp. 93-96)
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference
Goodship, T.H.; Cook, H.T.; Fakhouri, F.; Fervenza, F.C.; Fremeaux-Bacchi, V.; Kavanagh, D.; Nester, C.M.; Noris, M.; Pickering, M.C.; Cordoba, S.; Roumenina, L.T.; Sethi, S.; Smith, R.J.; Kar, N.C. van de ; et al. et al. sine al.
2017, Article / Letter to editor (Kidney International. Supplement, vol. 91, iss. 3, (2017), pp. 539-551)
Re: Bevill et al.: The Modern Metabolic Stone Evaluation in Children (Urology 2017;101:15-20)
Schreuder, M.F. ; Kar, N.C.A.J. van de
2017, Article / Letter to editor (Urology, vol. 102, (2017), pp. 267-268)
REducing STEroids in Relapsing Nephrotic syndrome: the RESTERN study- protocol of a national, double-blind, randomised, placebo-controlled, non-inferiority intervention study
Schijvens, A.M.; Dorresteijn, E.M.; Roeleveld, N. ; Heine, R. ter ; Wijk, J.A. van; Bouts, A.H.M.; Keijzer-Veen, M.G.; Kar, N.C.A.J. van de ; Heuvel, L.P.W.J. van den ; Schreuder, M.F.
2017, Article / Letter to editor (BMJ Open, vol. 7, iss. 9, (2017), pp. e018148)
Serological and genetic complement alterations in infection-induced and complement-mediated haemolytic uremic syndrome
Westra, D. ; Volokhina, E.B. ; Molen, R.G. van der ; Velden, T.J.A.M. van der ; Jeronimus-Klaasen, A.; Goertz, J.H.C. ; Gracchi, V.; Dorresteijn, E.M.; Bouts, A.H.; Keijzer-Veen, M.G.; Wijk, J.A. van; Bakker, J.A.; Roos, A. de; Heuvel, L.P.W.J. van den ; Kar, N.C.A.J. van de et al. sine al.
2017, Article / Letter to editor (Pediatric Nephrology, vol. 32, iss. 2, (2017), pp. 297-309)
Living Donor Kidney Transplantation in Atypical Hemolytic Uremic Syndrome: A Case Series
Duineveld, C. ; Verhave, J.C. ; Berger, Stefan P.; Kar, N.C.A.J. van de ; Wetzels, J.F.M.
2017, Article / Letter to editor (American Journal of Kidney Diseases, vol. 70, iss. 6, (2017), pp. 770-777)
Unusual severe case of hemolytic uremic syndrome due to Shiga toxin 2d-producing E. coli O80:H2
Wijnsma, K.L. ; Schijvens, A.M.; Rossen, J.W.; Kooistra-Smid, A.; Schreuder, M.F. ; Kar, N.C.A.J. van de
2017, Article / Letter to editor (Pediatric Nephrology, vol. 32, iss. 7, (2017), pp. 1263-1268)
Development and Pretesting of a Questionnaire to Assess Patient Experiences and Satisfaction with Medications (PESaM Questionnaire)
Kimman, M.L.; Rotteveel, A.H.; Wijsenbeek, M.; Mostard, R.; Tak, N.C.; Jaarsveld, X. van; Storm, M.; Wijnsma, K.L. ; Gelens, M.; Kar, N.C.A.J. van de ; Wetzels, J. ; Dirksen, C.D. et al. sine al.
2017, Article / Letter to editor (Patient-Patient Centered Outcomes Research, vol. 10, iss. 5, (2017), pp. 629-642)
Eculizumab Dosing Regimen in Atypical HUS: Possibilities for Individualized Treatment
Volokhina, E.B. ; Wijnsma, K.L. ; Molen, R.G. van der ; Roeleveld, N. ; Velden, T.J. van der ; Goertz, J.H.C. ; Sweep, C.G.J. ; Bruggemann, R.J.M. ; Wetzels, J. ; Kar, N.C. van de ; Heuvel, L.P. van den et al. sine al.
2017, Article / Letter to editor (Clinical Pharmacology and Therapeutics, vol. 102, iss. 4, (2017), pp. 671-678)
An international consensus approach to the management of atypical hemolytic uremic syndrome in children
Loirat, C.; Fakhouri, F.; Ariceta, G.; Besbas, N.; Bitzan, M.; Bjerre, A.; Coppo, R.; Emma, F.; Johnson, S.; Karpman, D.; Landau, D.; Langman, C.B.; Lapeyraque, A.L.; Licht, C.; Nester, C.; Pecoraro, C.; Riedl, M.; Kar, N.C.A.J. van de ; Walle, J. Vande; Vivarelli, M.; Fremeaux-Bacchi, V. et al. sine al.
2016, Article / Letter to editor (Pediatric Nephrology, vol. 31, iss. 1, (2016), pp. 15-39)
Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome
Greenbaum, L.A.; Fila, M.; Ardissino, G.; Al-Akash, S.I.; Evans, J.; Henning, P.; Lieberman, K.V.; Maringhini, S.; Pape, L.; Rees, L.; Kar, N.C. van de ; Walle, J. Vande; Ogawa, M.; Bedrosian, C.L.; Licht, C. et al. sine al.
2016, Article / Letter to editor (Kidney International. Supplement, vol. 89, iss. 3, (2016), pp. 701-711)
Drug-Drug Interactions in Treatment Using Azole Antifungal Agents
Schreuder, M.F. ; Kar, N.C.A.J. van de ; Bruggemann, R.J.M.
2016, Article / Letter to editor (Jama : Journal of the American Medical Association, vol. 315, iss. 23, (2016), pp. 2622)
A young girl with an unusual cause of acute kidney injury: Questions
Binkhorst, M. ; Wijnsma, K.L. ; Steenbergen, E.J.; Kar, N.C.A.J. van de ; Schreuder, M.F.
2016, Article / Letter to editor (Pediatric Nephrology, vol. 31, iss. 11, (2016), pp. 2071-2073)
Fecal diagnostics in combination with serology: best test to establish STEC-HUS
Wijnsma, K.L. ; Bommel, S.A. van; Velden, T. van der; Volokhina, E.; Schreuder, M.F. ; Heuvel, L.P.W.J. van den ; Kar, N.C.A.J. van de
2016, Article / Letter to editor (Pediatric Nephrology, vol. 31, iss. 11, (2016), pp. 2163-2170)
A young girl with an unusual cause of acute kidney injury: Answers
Binkhorst, M. ; Wijnsma, K.L. ; Steenbergen, E.J.; Kar, N.C.A.J. van de ; Schreuder, M.F.
2016, Article / Letter to editor (Pediatric Nephrology, vol. 31, iss. 11, (2016), pp. 2075-2078)
Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease
Maten, E. van der; Westra, D. ; Selm, S. van ; Langereis, J.D. ; Bootsma, H.J. ; Opzeeland, F.J.H. van ; Groot, R. de ; Ruseva, M.M.; Pickering, M.C.; Heuvel, L.P. van den ; Kar, N.C.A.J. van de ; Jonge, M.I. de ; Flier, M. van der et al. sine al.
2016, Article / Letter to editor (The Journal of Infectious Diseases, vol. 213, iss. 11, (2016), pp. 1820-1827)
Discontinuation of eculizumab maintenance treatment for atypical hemolytic uremic syndrome
Wetzels, J.F.M. ; Kar, N.C.A.J. van de
2015, Article / Letter to editor (American Journal of Kidney Diseases, vol. 65, iss. 2, (2015), pp. 342)
Advances and challenges in the management of complement-mediated thrombotic microangiopathies
Davin, J.C.; Kar, N.C.A.J. van de
2015, Article / Letter to editor (Therapeutic Advances in Hematology, vol. 6, iss. 4, (2015), pp. 171-185)
KOUNCIL: Kidney-Oriented Understanding of Correcting Ciliopathies.
Stokman, M.; Oud, M.; Reeuwijk, J. van ; Lilien, M.; Kar, N.C. van de ; Nijman, I.; Gilissen, C.; Kroes, H.Y.; Bongers, E.M.H.F. ; Geijsen, N.; Kamsteeg, E.J. ; Cuppen, E.; Roepman, R. ; Giles, R.; Renkema, K.Y. ; Arts, H.; Knoers, N.V.A.M. et al. sine al.
2015, Article / Letter to editor (Cilia, vol. 4, iss. 1, (2015), pp. 2530-2534)
Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo
Volokhina, E.B. ; Bergseth, G.; Kar, N.C.A.J. van de ; Heuvel, L.P.W.J. van den ; Mollnes, T.E.
2015, Article / Letter to editor (Blood, vol. 126, iss. 2, (2015), pp. 278-279)
Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome
Volokhina, E.B. ; Kar, N.C.A.J. van de ; Bergseth, G.; Velden, T.J.A.M. van der ; Westra, D. ; Wetzels, J.F.M. ; Heuvel, L.P.W.J. van den ; Mollnes, T.E.
2015, Article / Letter to editor (Clinical Immunology, vol. 160, iss. 2, (2015), pp. 237-243)
Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission
Volokhina, E.B. ; Westra, D. ; Velden, T.J.A.M. van der ; Kar, N.C.A.J. van de ; Mollnes, T.E.; Heuvel, B. van den
2015, Article / Letter to editor (Clinical and Experimental Immunology, vol. 181, iss. 2, (2015), pp. 306-313)
An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome.
Johnson, S.; Stojanovic, J.; Ariceta, G.; Bitzan, M.; Besbas, N.; Frieling, M.; Karpman, D.; Landau, D.; Langman, C.; Licht, C.; Pecoraro, C.; Riedl, M.; Siomou, E.; Kar, N.C. van de ; Walle, J.V.; Loirat, C.; Taylor, C.M. et al. sine al.
2014, Article / Letter to editor (Pediatric Nephrology, vol. 29, iss. 10, (2014), pp. 1967-1978)
Novel aspects of atypical haemolytic uraemic syndrome and the role of eculizumab
Verhave, J.C. ; Wetzels, J.F. ; Kar, N.C. van de
2014, Article / Letter to editor (Nephrology, Dialysis, Transplantation, vol. 29, iss. suppl 4, (2014), pp. iv131-iv141)
Severe infantile Bordetella pertussis pneumonia in monozygotic twins with a congenital C3 deficiency
Kurvers, R.A.J. ; Westra, D. ; Heijst, A.F.J. van ; Walk, T.L.M.; Warris, A. ; Kar, N.C.A.J. van de
2014, Article / Letter to editor (European Journal of Pediatrics, vol. 173, iss. 12, (2014), pp. 1591-1594)
Compound heterozygous mutations in the C6 gene of a child with recurrent infections
Westra, D. ; Kurvers, R.A.; Heuvel, L.P.W.J. van den ; Wurzner, R.; Hoppenreijs, E.P.A.H. ; Flier, M. van der ; Kar, N.C.A.J. van de ; Warris, A.
2014, Article / Letter to editor (Molecular Immunology, vol. 58, iss. 2, (2014), pp. 201-205)
Refractory thrombotic thrombocytopenic purpura in a 16-year-old girl: successful treatment with bortezomib
Balen, T. van ; Schreuder, M.F. ; Jong, H. de ; Kar, N.C.A.J. van de
2014, Article / Letter to editor (European Journal of Haematology, vol. 92, iss. 1, (2014), pp. 80-82)
Cat induced Pasteurella multocida peritonitis in peritoneal dialysis: a case report and review of the literature.
Sol, P.M.; Kar, N.C.A.J. van de ; Schreuder, M.F.
2013, Article / Letter to editor (International Journal of Hygiene and Environmental Health, vol. 216, iss. 2, (2013), pp. 211-213)
Combined pulmonary hypertension and renal thrombotic microangiopathy in cobalamin C deficiency.
Komhoff, M.; Roofthooft, M.T.; Westra, D. ; Teertstra, T.K.; Losito, A.; Kar, N.C.A.J. van de ; Berger, R.M.
2013, Article / Letter to editor (Pediatrics (Evanston), vol. 132, iss. 2, (2013), pp. e540-4)
The challenge of managing hemophilia A and STEC-induced hemolytic uremic syndrome
Westra, D. ; Dorresteijn, E.M.; Beishuizen, A.; Heuvel, L.P. van den ; Brons, P.P.T. ; Kar, N.C. van de
2013, Article / Letter to editor (Pediatric Nephrology, vol. 28, iss. 2, (2013), pp. 349-352)
Living kidney transplantation in adult patients with atypical haemolytic uraemic syndrome
Verhave, J.C. ; Westra, D. ; Hamersvelt, H.W. van ; Helden, M. van; Kar, N.C.A.J. van de ; Wetzels, J.F.M.
2013, Article / Letter to editor (Netherlands Journal of Medicine, vol. 71, iss. 7, (2013), pp. 342-347)
Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count.
Dorresteijn, E.M.; Kar, N.C.A.J. van de ; Cransberg, K.
2012, Article / Letter to editor (Pediatric Nephrology, vol. 27, iss. 7, (2012), pp. 1193-1195)
Novel C3 mutation p.Lys65Gln in aHUS affects complement factor H binding.
Volokhina, E.; Westra, D. ; Xue, X.; Gros, P.; Kar, N.C. van de ; Heuvel, L.P. van den
2012, Article / Letter to editor (Pediatric Nephrology, vol. 27, iss. 9, (2012), pp. 1519-1524)
Atypical hemolytic uremic syndrome in children: complement mutations and clinical characteristics.
Geerdink, L.M.; Westra, D. ; Wijk, J.A. van; Dorresteijn, E.M.; Lilien, M.R.; Davin, J.C.; Komhoff, M.; Hoeck, K. van; Vlugt, A. van der; Heuvel, L.P.W.J. van den ; Kar, N.C.A.J. van de et al. sine al.
2012, Article / Letter to editor (Pediatric Nephrology, vol. 27, iss. 8, (2012), pp. 1283-1291)

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