Browsing by Author "Swinkels, D.W."

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Chronic Adherence to a Ketogenic Diet Modifies Iron Metabolism in Elite Athletes
McKay, A.K.A.; Peeling, Peter; Pyne, D.B.; Welvaert, Marijke; Tee, Nicolin; Leckey, J.J.; Swinkels, D.W. ; Laarakkers, C.M. ; Burke, L.M.
2019, Article / Letter to editor (Medicine and Science in Sports and Exercise, vol. 51, iss. 3, (2019), pp. 548-555)
Association of anemia with health-related quality of life and survival: a large population-based cohort study
Wouters, Hanneke J.C.M.; Klauw, Melanie M. van der; Witte, T.J. de ; Stauder, Reinhard; Swinkels, D.W. ; Wolffenbuttel, Bruce H.R.; Huls, G.A.
2019, Article / Letter to editor (Haematologica, vol. 104, iss. 3, (2019), pp. 468-476)
Iron handling by the human kidney: glomerular filtration and tubular reabsorption both contribute to urinary iron excretion
Raaij, S.E.G. van; Rennings, A.J.; Biemond, B.J.; Schols, S.E.M.; Wiegerinck, E.T.G. ; Roelofs, H.M.J. ; Hoorn, E.J.; Walsh, S.B.; Nijenhuis, T. ; Swinkels, D.W. ; Swelm, R.P.L. van et al. sine al.
2019, Article / Letter to editor (American Journal of Physiology : Renal Physiology, vol. 316, iss. 3, (2019), pp. 606-614)
Iron uptake by ZIP8 and ZIP14 in human proximal tubular epithelial cells
Raaij, S.E.G. van; Srai, S.K.S.; Swinkels, D.W. ; Swelm, R.P.L. van
2019, Article / Letter to editor (Biometals, vol. 32, iss. 2, (2019), pp. 211-226)
First-in-human Phase I studies of PRS-080#22, a hepcidin antagonist, in healthy volunteers and patients with chronic kidney disease undergoing hemodialysis
Renders, L.; Budde, K.; Rosenberger, C.; Swelm, R.P. van ; Swinkels, D.W. ; Dellanna, F.; Feuerer, W.; Wen, M.; Erley, C.; Bader, B.; Sommerer, C.; Schaier, M.; Meurer, K.; Matis, L. et al. sine al.
2019, Article / Letter to editor (PLoS One, vol. 14, iss. 3, (2019), article e0212023)
Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey
Hohlbaum, A.M.; Gille, H.; Trentmann, S.; Kolodziejczyk, M.; Rattenstetter, Barbara; Laarakkers, C.M. ; Swinkels, D.W. ; Swelm, R.P.L. van
2018, Article / Letter to editor (British Journal of Pharmacology, vol. 175, iss. 7, (2018), pp. 1054-1065)
Definition of Iron Deficiency Based on the Gold Standard of Bone Marrow Iron Staining in Heart Failure Patients
Beverborg, Niels Grote; Klip, I.T.; Meijers, Wouter C.; Voors, A.A.; Vegter, Eline L.; Wal, Haye H. van der; Swinkels, D.W. ; Veldhuisen, D.J. van; Meer, P. van der
2018, Article / Letter to editor (Circulation. Heart Failure, vol. 11, iss. 2, (2018), article e004519)
Iron deficiency impairs contractility of human cardiomyocytes through decreased mitochondrial function
Hoes, Martijn F.; Beverborg, Niels Grote; Kijlstra, J.David; Kuipers, Jeroen; Swinkels, D.W. ; Giepmans, Ben N.G.; Rodenburg, R.J. ; Boer, Rudolf A. de; Meer, P. van der
2018, Article / Letter to editor (European Journal of Heart Failure, vol. 20, iss. 5, (2018), pp. 910-919)
Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis
Swelm, R.P.L. van ; Vos, Madelon; Verhoeven, Frank; Thevenod, F.; Swinkels, D.W.
2018, Article / Letter to editor (Cell Death and Disease, vol. 9, (2018), article 550)
Inhibition of Nrf2 alters cell stress induced by chronic iron exposure in human proximal tubular epithelial cells
Raaij, S.E.G. van; Masereeuw (UU), R. ; Swinkels, D.W. ; Swelm, R.P.L. van
2018, Article / Letter to editor (Toxicology Letters, vol. 295, (2018), pp. 179-186)
Effects of Weekly Iron and Folic Acid Supplements on Malaria Risk in Nulliparous Women in Burkina Faso: A Periconceptional, Double-Blind, Randomized Controlled Noninferiority Trial
Gies, Sabine; Diallo, Salou; Roberts, Stephen A.; Kazienga, Adama; Powney, Matthew; Brabin, Loretta; Swinkels, D.W. ; Geurts-Moespot, A. ; Faragher, B.; Brabin, B.J.
2018, Article / Letter to editor (Journal of Infectious Diseases, vol. 218, iss. 7, (2018), pp. 1099-1109)
A Stepwise Procedure to Define a Data Collection Framework for a Clinical Biobank
Manders, P. ; Peters, T.M.; Siezen, A.E.; Rooij, I.A.L.M. van ; Snijder, R.; Swinkels, D.W. ; Zielhuis, G.A.
2018, Article / Letter to editor (Biopreservation and Biobanking, vol. 16, iss. 2, (2018), pp. 138-147)
Contributors and Hemochromatosis International Taskforce. Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype
Adams, P.; Altes, A.; Brissot, P.; Butzeck, B.; Cabantchik, I.; Cançado, R.; Distante, S.; Evans, P.; Evans, R.; Ganz, T.; Girelli, D.; Hultcrantz, R.; McLaren, G.; Marris, B.; Milman, N.; Nemeth, E.; Nielsen, P.; Pineau, B.; Piperno, A.; Porto, G.; Prince, D.; Ryan, J.; Sanchez, M.; Santos, P.; Swinkels, D.W. ; Teixeira, E.; Toska, K.; Vanclooster, A.; White, D.P. et al. sine al.
2018, Article / Letter to editor (Hepatology International, vol. 12, iss. 2, (2018), pp. 83-86)
Biochemical effects on the liver of 1 month of alcohol abstinence in moderate alcohol consumers
Munsterman, I.D.; Groefsema, M.M. ; Weijers, G. ; Klein, W.M. ; Swinkels, D.W. ; Drenth, J.P.H. ; Schellekens, A.F.A. ; Tjwa, E.T.L.L.
2018, Article / Letter to editor (Alcohol and Alcoholism, vol. 53, iss. 4, (2018), pp. 435-438)
Utility of zinc protoporphyrin in management of whole blood donors
Schotten, N; Zalpuri, Saurabh; Pasker-de Jong, Pieternel C. M.; Swinkels, D.W. ; Hurk, Katja van den; Kort, W.L. de; Kraaij, Marian G.J. van ; Noord, P.A.H. van
2018, Article / Letter to editor (Transfusion, vol. 58, iss. 3, (2018), pp. 692-700)
The Radboud Biobank: A Central Facility for Disease-Based Biobanks to Optimise Use and Distribution of Biomaterial for Scientific Research in the Radboud University Medical Center, Nijmegen
Manders, P. ; Lutomski, J.E.; Smit, C.; Swinkels, D.W. ; Zielhuis, G.A.
2018, Article / Letter to editor (Open Journal of Bioresources, vol. 5, (2018), pp. 2)
Role of the Complement System in Chronic Central Serous Chorioretinopathy A Genome-Wide Association Study
Schellevis, R.L.; Dijk, E.H.C. van; Breukink, M.B.; Altay, L.; Bakker, B.; Koeleman, Bobby P. C.; Kiemeney, L.A. ; Swinkels, D.W. ; Keunen, J.E. ; Hoyng, C.B. ; Hollander, A.I. den ; Boon, C.J.F. ; Jong, E.K. de et al. sine al.
2018, Article / Letter to editor (Jama Ophthalmology, vol. 136, iss. 10, (2018), pp. 1128-1136)
The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2
Riley, Lisa G.; Heeney, Matthew M.; Rudinger-Thirion, Joelle; Frugier, Magali; Campagna, Dean R.; Zhou, Ronghao; Simons, A. ; Schaap, N.P. ; Rodenburg, R.J. ; Kleefstra, T. ; Swinkels, D.W. ; Christodoulou, John; Fleming, Mark D. et al. sine al.
2018, Article / Letter to editor (Haematologica, vol. 103, iss. 12, (2018), pp. 2008-2015)
Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes
Swart, L. de; Reiniers, Chloe; Bagguley, Timothy; Marrewijk, C.J. van ; Bowen, D.; Hellstrom-Lindberg, E.; Blijlevens, N.M. ; Langemeijer, S.M.C. ; Droste, J.A.H. ; Swinkels, D.W. ; Smith, A.; Witte, T.J.M. de et al. sine al.
2018, Article / Letter to editor (Haematologica, vol. 103, iss. 1, (2018), pp. 69-79)
Tubular iron deposition and iron handling proteins in human healthy kidney and chronic kidney disease
Raaij, S.E.G. van; Swelm, R.P.L. van ; Bouman, K.; Cliteur, Maaike; Heuvel, M van den; Pertijs, J.C. ; Goor, H van; Srai, S.K.S.; Swinkels, D.W.
2018, Article / Letter to editor (Scientific Reports, vol. 8, (2018), article 9353)
An intensified training schedule in recreational male runners is associated with increases in erythropoiesis and inflammation and a net reduction in plasma hepcidin
Moretti, D.; Mettler, S.; Zeder, C.; Lundby, C.; Geurts-Moespot, A. ; Monnard, A.; Swinkels, D.W. ; Brittenham, G.M.; Zimmermann, M.B.
2018, Article / Letter to editor (The American Journal of Clinical Nutrition, vol. 108, iss. 6, (2018), pp. 1324-1333)
Loss-of-function ferroportin disease: novel mechanistic insights and unanswered questions
Vlasveld, L.T.; Swinkels, D.W.
2018, Article / Letter to editor (Haematologica, vol. 103, iss. 11, (2018), pp. 1753-1755)
Variable workup calls for guideline development for type 2A hereditary haemochromatosis
Smit, S.L.; Peters, T.M.A.; Gisbertz, I.A.M.; Moolenaar, W.; Hendriks, Y.; Vincent, H.H.; Herwaarden, A.E. van ; Rennings, A.J.; Swinkels, D.W.
2018, Article / Letter to editor (Netherlands Journal of Medicine, vol. 76, iss. 8, (2018), pp. 365-373)
Oral iron supplementation: Potential implications for the gut microbiome and metabolome in patients with CKD
Kortman, G.A.M.; Reijnders, D.; Swinkels, D.W.
2017, Article / Letter to editor (Hemodialysis International, vol. 21, iss. 1, (2017), pp. S28-S36)
Pharmacokinetics of Ferric Pyrophosphate Citrate, a Novel Iron Salt, Administered Intravenously to Healthy Volunteers
Pratt, R.D.; Swinkels, D.W. ; Ikizler, T.A.; Gupta, A.
2017, Article / Letter to editor (Journal of Clinical Pharmacology and Journal of New Drugs, vol. 57, iss. 3, (2017), pp. 312-320)
TFR2-related haemochromatosis in the Netherlands: a cause of arthralgia in young adulthood
Peters, T.M.; Meulders, A.F.; Redert, K.; Cuijpers, M.L.; Rennings, A.J.; Janssen, M.C.H. ; Blijlevens, N.M.A. ; Swinkels, D.W.
2017, Article / Letter to editor (Netherlands Journal of Medicine, vol. 75, iss. 2, (2017), pp. 56-64)
Factors influencing the post-exercise hepcidin-25 response in elite athletes
Peeling, P.; McKay, A.K.A.; Pyne, D.B.; Guelfi, K.J.; McCormick, R.H.; Laarakkers, C.M. ; Swinkels, D.W. ; Garvican-Lewis, L.A.; Ross, M.L.R.; Sharma, A.P.; Leckey, J.J.; Burke, L.M. et al. sine al.
2017, Article / Letter to editor (European Journal of Applied Physiology, vol. 117, iss. 6, (2017), pp. 1233-1239)
Live high, train low - influence on resting and post-exercise hepcidin levels.
Govus, A.D.; Peeling, P.; Abbiss, C.R.; Lawler, N.G.; Swinkels, D.W. ; Laarakkers, C.M. ; Thompson, K.G.; Peiffer, J.J.; Gore, C.J.; Garvican-Lewis, L.A.
2017, Article / Letter to editor (Scandinavian Journal of Medicine & Science in Sports, vol. 27, iss. 7, (2017), pp. 704-713)
Prediction of human iron bioavailability using rapid c-ELISAs for human plasma hepcidin
Stoffel, N.U.; Zeder, C.; Fort, E.; Swinkels, D.W. ; Zimmermann, M.B.; Moretti, D.
2017, Article / Letter to editor (Clinical Chemistry and Laboratory Medicine, vol. 55, iss. 8, (2017), pp. 1186-1192)
Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials
Stoffel, N.U.; Cercamondi, C.I.; Brittenham, G.; Zeder, C.; Geurts-Moespot, A. ; Swinkels, D.W. ; Moretti, D.; Zimmermann, M.B.
2017, Article / Letter to editor (Lancet Haematology, vol. 4, iss. 11, (2017), pp. 524-533)
Serum ferritin and risk for new-onset heart failure and cardiovascular events in the community
Klip, I.T.; Voors, A.A.; Swinkels, D.W. ; Bakker, S.J.L.; Kootstra-Ros, J.E.; Lam, C.S.; Harst, P. van der; Veldhuisen, D.J. van; Meer, P. van der
2017, Article / Letter to editor (European Journal of Heart Failure, vol. 19, iss. 3, (2017), pp. 348-356)
Cohort Profile: The Nijmegen Biomedical Study (NBS)
Galesloot, T.E.; Vermeulen, S.H. ; Swinkels, D.W. ; Vegt, F. de ; Franke, B. ; Heijer, M. den ; Graaf, J. de ; Verbeek, A.L.M. ; Kiemeney, L.A.
2017, Article / Letter to editor (International Journal of Epidemiology, vol. 46, iss. 4, (2017), pp. 1099-1100j)
Interleukin-6 and Hepcidin Levels during Hormone-Deplete and Hormone-Replete Phases of an Oral Contraceptive Cycle: A Pilot Study
Sim, M.; Dawson, B.; Landers, G.; Swinkels, D.W. ; Wiegerinck, E.T.G. ; Yeap, B.B.; Trinder, D.; Peeling, P.
2017, Article / Letter to editor (Annals of Nutrition & Metabolism, vol. 70, iss. 2, (2017), pp. 100-105)
Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption
Staron, R.; Lipinski, P.; Lenartowicz, M.; Bednarz, A.; Gajowiak, A.; Smuda, E.; Krzeptowski, W.; Pieszka, M.; Korolonek, T.; Hamza, I.; Swinkels, D.W. ; Swelm, R.P.L. van ; Starzynski, R.R. et al. sine al.
2017, Article / Letter to editor (PLoS One, vol. 12, iss. 7, (2017), article e0181117)
EPO and hepcidin plasma concentrations in blood donors and β-thalassemia intermedia are not related to commercially tested plasma ERFE concentrations
Schotten, N; Laarakkers, C.M. ; Roelofs, R.W.H.M. ; Origa, R.; Kraaij, M.G.J. van ; Swinkels, D.W.
2017, Article / Letter to editor (American Journal of Hematology, vol. 92, iss. 3, (2017), pp. 29-31)
A rare splice donor mutation in the haptoglobin gene associates with blood lipid levels and coronary artery disease.
Bjornsson, E.; Halldorsson, G.; Helgadottir, A.; Gylfason, A; Kehr, B.; Jonasdottir, A.; Sigurdsson, A.; Oddsson, A.; Thorleifsson, G.; Magnusson, O.T.; Gretarsdottir, S.; Kristjansson, R.P.; Asgeirsdottir, M.; Swinkels, D.W. ; Kiemeney, L.A. ; Eyjolfsson, G.I.; Sigurdardottir, O.; Masson, G.; Olafsson, I.; Thorgeirsson, G.; Holm, H.; Thorsteinsdottir, U.; Gudbjartsson, D.F.; Sulem, P.; Stefansson, K. et al. sine al.
2017, Article / Letter to editor (Human Molecular Genetics, vol. 26, iss. 12, (2017), pp. 2364-2376)
Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury.
Swelm, R.P. van ; Wetzels, J.F. ; Verweij, V.G. ; Laarakkers, C.M. ; Pertijs, J.C. ; Wijst, J.A. van der ; Thevenod, F.; Masereeuw, R. ; Swinkels, D.W.
2016, Article / Letter to editor (Journal of the American Society of Nephrology, vol. 27, iss. 9, (2016), pp. 2720-2732)
Cardiac Hepcidin Expression Associates with Injury Independent of Iron
Breda, G.F. van; Bongartz, L.G.; Zhuang, W.; Swelm, R.P.L. van ; Pertijs, J.; Braam, B.; Cramer, M.J.; Swinkels, D.W. ; Doevendans, P.A.; Verhaar, M.C.; Masereeuw, R. ; Joles, J.A.; Gaillard, C.A. et al. sine al.
2016, Article / Letter to editor (American Journal of Nephrology, vol. 44, iss. 5, (2016), pp. 368-378)
Catalytic iron and acute kidney injury
Leaf, D.E.; Swinkels, D.W.
2016, Article / Letter to editor (American Journal of Physiology : Renal Physiology, vol. 311, iss. 5, (2016), pp. F871-F876)
EHA Roadmap for European Hematology Research. The European Hematology Association Roadmap for European Hematology Research: a consensus document
Engert, A.; Balduini, C.; Brand, Anneke ; Coiffier, B.; Cordonnier, C.; Döhner, H.; Wit, T.D. de; Eichinger, S.; Fibbe, W.; Green, T.; Haas, F. de; Iolascon, A.; Jaffredo, T.; Rodeghiero, F.; Salles, G.; Schuringa, J.J.; Swinkels, D.W. ; Huls, G.A.; Donnelly, P. ; et al. et al. sine al.
2016, Article / Letter to editor (Haematologica, vol. 101, iss. 2, (2016), pp. 115-208)
Toward Worldwide Hepcidin Assay Harmonization: Identification of a Commutable Secondary Reference Material
Vorm, L.N. van der; Hendriks, J.C.M. ; Laarakkers, C.M. ; Klaver, S.; Armitage, A.E.; Bamberg, A.; Geurts-Moespot, A.J.; Girelli, D.; Herkert, M.; Itkonen, O.; Konrad, R.J.; Tomosugi, N.; Westerman, M.; Bansal, S.S.; Campostrini, N.; Drakesmith, H.; Fillet, M.; Olbina, G.; Pasricha, S.R.; Pitts, K.R.; Sloan, J.H.; Tagliaro, F.; Weykamp, C.W.; Swinkels, D.W. et al. sine al.
2016, Article / Letter to editor (Clinical Chemistry, vol. 62, iss. 7, (2016), pp. 993-1001)
Course of iron parameters in HFE-hemochromatosis patients during initial treatment with erythrocytapheresis compared to phlebotomy
Rombout-Sestrienkova, E.; Koek, G.H.; Neslo, R.; Kraaij, M. van; Menheere, P.P.; Masclee, A.; Swinkels, D.W.
2016, Article / Letter to editor (Journal of Clinical Apheresis, vol. 31, iss. 6, (2016), pp. 564-570)
Safety, pharmacokinetics and pharmacodynamics of the anti-hepcidin Spiegelmer lexaptepid pegol in healthy subjects
Boyce, M.; Warrington, S.; Cortezi, B.; Zöllner, S.; Vauléon, S.; Swinkels, D.W. ; Summo, L.; Schwoebel, F.; Riecke, K.
2016, Article / Letter to editor (British Journal of Pharmacology, vol. 173, iss. 10, (2016), pp. 1580-1588)
Hepcidin in the diagnosis of iron disorders
Girelli, D.; Nemeth, E.; Swinkels, D.W.
2016, Article / Letter to editor (Blood, vol. 127, iss. 23, (2016), pp. 2809-2813)
Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders
Swart, L. de; Hendriks, J.C.M. ; Vorm, L.N. van der; Cabantchik, Z.I.; Evans, P.J.; Hod, E.A.; Brittenham, G.M.; Furman, Y.; Wojczyk, B.; Janssen, M.C.H. ; Porter, J.B.; Mattijssen, V.E.; Biemond, B.J.; MacKenzie, M.A. ; Origa, R.; Galanello, R.; Hider, R.C.; Swinkels, D.W. et al. sine al.
2016, Article / Letter to editor (Haematologica, vol. 101, iss. 1, (2016), pp. 38-45)
Seven days of high carbohydrate ingestion does not attenuate post-exercise IL-6 and hepcidin levels
Badenhorst, C.E.; Dawson, B.; Cox, G.R.; Sim, M.; Laarakkers, C.M. ; Swinkels, D.W. ; Peeling, P.
2016, Article / Letter to editor (European Journal of Applied Physiology, vol. 116, iss. 9, (2016), pp. 1715-1724)
The donation interval of 56 days requires extension to 180 days for whole blood donors to recover from changes in iron metabolism
Schotten, N.; Pasker-de Jong, P.C.M. ; Moretti, D.; Zimmermann, M.B.; Geurts-Moespot, A.J.; Swinkels, D.W. ; Kraaij, M.G.J. van
2016, Article / Letter to editor (Blood, vol. 128, iss. 17, (2016), pp. 2185-2188)
Iron refractory iron deficiency anemia: a heterogeneous disease that is not always iron refractory
Donker, A.E.; Schaap, C.C.; Novotny, V.M.J. ; Smeets, R.; Peters, T.M.; Heuvel, B.L. van den; Raphael, M.F.; Rijneveld, A.W.; Appel, I.M.; Vlot, A.J.; Versluijs, A.B.; Gelder, M. van; Granzen, B.; Janssen, M.C.H. ; Rennings, A.J.; Veerdonk, F.L. van de ; Brons, P.P.T. ; Bakkeren, D.L.; Nijziel, M.R.; Vlasveld, L.T.; Swinkels, D.W. et al. sine al.
2016, Article / Letter to editor (American Journal of Hematology, vol. 91, iss. 12, (2016), pp. E482-e490)
Hyperferritinemia and iron metabolism in Gaucher disease: Potential pathophysiological implications
Regenboog, M.; Kuilenburg, A.B. van; Verheij, J.; Swinkels, D.W. ; Hollak, C.E.M.
2016, Article / Letter to editor (Blood Reviews, vol. 30, iss. 6, (2016), pp. 431-437)
Microbial Metabolism Shifts Towards an Adverse Profile with Supplementary Iron in the TIM-2 In vitro Model of the Human Colon
Kortman, G.A.; Dutilh, B.E. ; Maathuis, A.J.; Engelke, U.F. ; Boekhorst, J. ; Keegan, K.P.; Nielsen, F.G.; Betley, J.; Weir, J.C.; Kingsbury, Z.; Kluijtmans, L.A. ; Swinkels, D.W. ; Venema, K.; Tjalsma, H. et al. sine al.
2016, Article / Letter to editor (Frontiers in Microbiology, vol. 6, iss. 6, (2016), pp. 1481)

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