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2012Bioeffect modeling and equieffective dose concepts in radiation oncology - Terminology, quantities and unitsBentzen, S.M.; Dorr, W.; Gahbauer, R.; Howell, R.W.; Joiner, M.C.; Jones, B.; Jones, D.T.; van der Kogel, A.J.; Wambersie, A.; Whitmore, G.
201264Cu-ATSM and 18FDG PET uptake and 64Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry.Hansen, A.E.; Kristensen, A.T.; Jorgensen, J.T.; McEvoy, F.J.; Busk, M.; Kogel, A.J. van der; Bussink, J.; Engelholm, S.A.; Kjaer, A.
2012Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial.Janssens, G.O.R.J.; Rademakers, S.E.; Terhaard, C.H.J.; Doornaert, P.A.; Bijl, H.P.; Ende, P. van den; Chin, A.; Marres, H.A.M.; Bree, R. de; Kogel, A.J. van der; Hoogsteen, I.J.; Bussink, J.; Span, P.N.; Kaanders, J.H.A.M.
2012Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neckStegeman, H.; Kaanders, J.H.A.M.; Wheeler, D.L.; van der Kogel, A.J.; Verheijen, M.M.; Waaijer, S.J.; Iida, M.; Grenman, R.; Span, P.N.; Bussink, J.
2012(64)Cu-ATSM and (18)FDG PET uptake and (64)Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistryHansen, A.E.; Kristensen, A.T.; Jorgensen, J.T.; McEvoy, F.J.; Busk, M.; van der Kogel, A.J.; Bussink, J.; Engelholm, S.A.; Kjaer, A.
2012Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancerRoe, K.; Mikalsen, L.T.; van der Kogel, A.J.; Bussink, J.; Lyng, H.; Ree, A.H.; Marignol, L.; Olsen, D.R.
2012Spinal cord tolerance to reirradiation with single-fraction radiosurgery: a swine model.Medin, P.M.; Foster, R.D.; Kogel, A.J. van der; Sayre, J.W.; McBride, W.H.; Solberg, T.D.
2011Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1alpha, CAIX, LDH-5, GLUT-1, MCT1 and MCT4Rademakers, S.E.; Lok, J.; van der Kogel, A.J.; Bussink, J.; Kaanders, J.H.A.M.
2011Expression of E-cadherin and vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patientsNijkamp, M.M.; Span, P.N.; Hoogsteen, I.J.; van der Kogel, A.J.; Kaanders, J.H.A.M.; Bussink, J.
2011Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fractionRouschop, K.M.; Dubois, L.; Schaaf, M.B.; Beucken, T. van den; Lieuwes, N.; Keulers, T.G.; Savelkouls, K.G.; Bussink, J.; Kogel, A.J. van der; Koritzinsky, M.; Wouters, B.G.
2011Spinal cord tolerance to single-fraction partial-volume irradiation: a swine modelMedin, P.M.; Foster, R.D.; Kogel, A.J. van der; Sayre, J.W.; McBride, W.H.; Solberg, T.D.
2011Parametric mapping of immunohistochemically stained tissue sections; a method to quantify the colocalization of tumor markersRademakers, S.E.; Rijken, P.F.J.W.; Peeters, W.J.M.; Nijkamp, M.M.; Barber, P.R.; Laak, J.A.W.M. van der; Kogel, A.J. van der; Bussink, J.; Kaanders, J.H.A.M.
2011Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imagingDubois, L.J.; Lieuwes, N.G.; Janssen, M.H.; Peeters, W.J.M.; Windhorst, A.D.; Walsh, J.C.; Kolb, H.C.; Ollers, M.C.; Bussink, J.; Dongen, G.A. van; Kogel, A.J. van der; Lambin, P.
2011Spatial relationship of phosphorylated epidermal growth factor receptor and activated AKT in head and neck squamous cell carcinomaNijkamp, M.M.; Hoogsteen, I.J.; Span, P.N.; Takes, R.P.; Lok, J.; Rijken, P.F.J.W.; van der Kogel, A.J.; Bussink, J.; Kaanders, J.H.A.M.
2011Characterization of positron emission tomography hypoxia tracer uptake and tissue oxygenation via electrochemical modelingBowen, S.R.; Kogel, A.J. van der; Nordsmark, M.; Bentzen, S.M.; Jeraj, R.
2010Assessment of Blood Hemodynamics by USPIO-Induced R(1) Changes in MRI of Murine Colon Carcinoma.Laarhoven, H.W.M. van; Philippens, M.E.P.; Peeters, W.J.M.; Rijken, P.F.J.W.; Kogel, A.J. van der; Punt, C.J.A.; Heerschap, A.
2010Benign uterine uptake of FDG: a case report and review of literature.Vriens, D.; Geus-Oei, L.F. de; Flucke, U.E.; Kogel, A.J. van der; Oyen, W.J.G.; Vierhout, M.E.; Meer, J.W.M. van der
2010Radiation dose-volume effects in the spinal cord.Kirkpatrick, J.P.; Kogel, A.J. van der; Schultheiss, T.E.
2010Innovations in radiotherapy planning of head and neck cancers: role of PET.Troost, E.G.C.; Schinagl, D.A.X.; Bussink, J.; Boerman, O.C.; Kogel, A.J. van der; Oyen, W.J.G.; Kaanders, J.H.A.M.
2010Longitudinal magnetic resonance imaging-based assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgen-exposed and androgen-deprived conditions.Roe, K.; Seierstad, T.; Kristian, A.; Mikalsen, L.T.; Maelandsmo, G.M.; Kogel, A.J. van der; Ree, A.H.; Olsen, D.R.
2010The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.Rouschop, K.M.; Beucken, T. van den; Dubois, L.; Niessen, H.; Bussink, J.; Savelkouls, K.; Keulers, T.; Mujcic, H.; Landuyt, W.; Voncken, J.W.; Lambin, P.; Kogel, A.J. van der; Koritzinsky, M.; Wouters, B.G.
2010Effect of cetuximab and fractionated irradiation on tumour micro-environment.Santiago, A.; Eicheler, W.; Bussink, J.; Rijken, P.F.J.W.; Yaromina, A.; Beuthien-Baumann, B.; Kogel, A.J. van der; Baumann, M.; Krause, M.
2010Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors.Kruser, T.J.; Wheeler, D.L.; Armstrong, E.A.; Iida, M.; Kozak, K.R.; Kogel, A.J. van der; Bussink, J.; Coxon, A.; Polverino, A.; Harari, P.M.
2010Histopathologic validation of 3'-deoxy-3'-18F-fluorothymidine PET in squamous cell carcinoma of the oral cavity.Troost, E.G.C.; Bussink, J.; Slootweg, P.J.; Peeters, W.J.M.; Merkx, M.A.W.; Kogel, A.J. van der; Oyen, W.J.G.; Kaanders, J.H.A.M.
2009Bath and shower effect in spinal cord: the effect of time interval.Philippens, M.E.P.; Pop, L.A.M.; Visser, A.G.; Peeters, W.J.M.; Kogel, A.J. van der
2009Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response.Beucken, T. van den; Koritzinsky, M.; Niessen, H.; Dubois, L.; Savelkouls, K.; Mujcic, H.; Jutten, B.; Kopacek, J.; Pastorekova, S.; Kogel, A.J. van der; Lambin, P.; Voncken, W.; Rouschop, K.M.; Wouters, B.G.
2009Radiation effects in the rat spinal cord : evaluation with apparent diffusion coefficient versus T2 at serial MR imagingPhilippens, M.E.P.; Gambarota, G.; Kogel, A.J. van der; Heerschap, A.
2009No detectable hypoxia in malignant salivary gland tumors: preliminary results.Wijffels, K.I.E.M.; Hoogsteen, I.J.; Lok, J.; Rijken, P.F.J.W.; Marres, H.A.M.; Wilde, P.C.M. de; Kogel, A.J. van der; Kaanders, J.H.A.M.
2009Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia.Hoogsteen, I.J.; Lok, J.; Marres, H.A.M.; Takes, R.P.; Rijken, P.F.J.W.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2009Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?Busk, M.; Horsman, M.R.; Jakobsen, S.; Hansen, K.V.; Bussink, J.; Kogel, A.J. van der; Overgaard, J.
2009Angiogenesis, hypoxia and VEGF expression during tumour growth in a human xenograft tumour model.Hendriksen, E.M.; Span, P.N.; Schuuring, J.; Peters, J.P.W.; Sweep, F.C.; Kogel, A.J. van der; Bussink, J.
2008Clinical radiobiology in 2008.Begg, A.C.; Kogel, A.J. van der
2008Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: in regard to Evans et al. (Int J Radiat Oncol Biol Phys 2007;69:1024-1031).Bussink, J.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2008Molecular aspects of tumour hypoxiaRademakers, S.E.; Span, P.N.; Kaanders, J.H.A.M.; Sweep, C.G.J.; Kogel, A.J. van der; Bussink, J.
2008Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics.Thorsen, F.; Jirak, D.; Wang, J.; Sykova, E.; Bjerkvig, R.; Enger, P.O.; Kogel, A.J. van der; Hajek, M.
2008Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: a comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy.Busk, M.; Horsman, M.R.; Jakobsen, S.; Keiding, S.; Kogel, A.J. van der; Bussink, J.; Overgaard, J.
2008Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer.Bussink, J.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2008Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti-glioma therapy.Claes, A.; Schuuring, J.; Boots-Sprenger, S.; Hendriks-Cornelissen, S.; Dekkers, M.; Kogel, A.J. van der; Leenders, W.P.J.; Wesseling, P.; Jeuken, J.W.M.
2008Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas.Wijffels, K.I.E.M.; Marres, H.A.M.; Peters, J.P.W.; Rijken, P.F.J.W.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2008Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage.Busk, M.; Horsman, M.R.; Jakobsen, S.; Bussink, J.; Kogel, A.J. van der; Overgaard, J.
2008Aerobic glycolysis in cancers: implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia.Busk, M.; Horsman, M.R.; Kristjansen, P.E.; Kogel, A.J. van der; Bussink, J.; Overgaard, J.
2008Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI.Gambarota, G.; Leenders, W.P.J.; Maass, C.; Wesseling, P.; Kogel, A.J. van der; Tellingen, O van; Heerschap, A.
2008Correlation of [18F]FMISO autoradiography and pimonodazole immunohistochemistry in human head and neck carcinoma xenografts.Troost, E.G.C.; Laverman, P.; Philippens, M.E.P.; Lok, J.; Kogel, A.J. van der; Oyen, W.J.G.; Boerman, O.C.; Kaanders, J.H.A.M.; Bussink, J.
2007Tumorhypoxie en modificatie van hypoxie tijdens radiotherapieHoogsteen, I.J.; Marres, H.A.M.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2007Bij behandeling plaveiselcelcarcinomen in het hoofdhalsgebied: Radiotherapie en de epidermale groeifactorreceptorTroost, E.G.C.; Bussink, J.; Hoogsteen, I.J.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2007The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments.Hoogsteen, I.J.; Marres, H.A.M.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2007Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers.Ljungkvist, A.; Bussink, J.; Kaanders, J.H.A.M.; Kogel, A.J. van der
2007Microenvironmental transformations by VEGF- and EGF-receptor inhibition and potential implications for responsiveness to radiotherapy.Bussink, J.; Kaanders, J.H.A.M.; Kogel, A.J. van der
2007Tumor microenvironment in head and neck squamous cell carcinomas: predictive value and clinical relevance of hypoxic markers. A review.Hoogsteen, I.J.; Marres, H.A.M.; Bussink, J.; Kogel, A.J. van der; Kaanders, J.H.A.M.
2007Dose-volume effects in rat thoracolumbar spinal cord: the effects of nonuniform dose distribution.Philippens, M.E.P.; Pop, L.A.M.; Visser, A.G.; Kogel, A.J. van der

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