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2011Nephritogenic antibodies bind in glomeruli through interaction with exposed chromatin fragments and not with renal cross-reactive antigens.Mjelle, J.E.; Rekvig, O.P.; Vlag, J. van der; Fenton, K.A.
2011Lupus nephritis: role of antinucleosome autoantibodiesvan der Vlag, J.; Berden, J.H.M.
2011Regulatory and pathogenetic mechanisms of autoantibodies in SLERadic, M.; Herrmann, M.; Vlag, J. van der; Rekvig, O.P.
2011Epigenetic patterns maintained in early Caenorhabditis elegans embryos can be established by gene activity in the parental germ cellsArico, J.K.; Katz, D.J.; Vlag, J. van der; Kelly, W.G.
2011Improvement in chromatin maturity of human spermatozoa selected through density gradient centrifugationMateo, S. de; Ramos, L.; van der Vlag, J.; Boer, P. de; Oliva, R.
2011Nucleosomes and C1q bound to glomerular endothelial cells serve as targets for autoantibodies and determine complement activationO'Flynn, J.; Flierman, R.; Pol, P. van der; Meulemans-Rops, L.W.M.; Satchell, S.C.; Mathieson, P.W.; Kooten, C. van; Vlag, J. van der; Berden, J.H.M.; Daha, M.R.
2011Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathwayNijenhuis, T.; Sloan, A.J.; Hoenderop, J.G.J.; Flesche, J.; Goor, H. van; Kistler, A.D.; Bakker, M.; Bindels, R.J.M.; Boer, R.A. de; Moller, C.C.; Hamming, I.; Navis, G.; Wetzels, J.F.M.; Berden, J.H.M.; Reiser, J.; Faul, C.; Vlag, J. van der
2011Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosusBavel, C.C.A.W. van; Dieker, J.W.C.; Kroeze, Y.L.; Tamboer, W.P.M.; Voll, R.; Muller, S.; Berden, J.H.M.; Vlag, J. van der
2011Synchronized turbo apoptosis induced by cold-shockFransen, J.H.; Dieker, J.W.C.; Hilbrands, L.B.; Berden, J.H.M.; van der Vlag, J.
2010The role of dendritic cells in the pathogenesis of systemic lupus erythematosus.Fransen, J.H.; Vlag, J. van der; Ruben, J.; Adema, G.J.; Berden, J.H.M.; Hilbrands, L.B.
2010A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx.Sluis, G.L. Van; Nieuwdorp, M.; Kamphuisen, T.P.W.; Vlag, J. van der; Noorden, C.J.F. van; Spek, C.A.
2010The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology.Rops, A.L.; Figdor, C.G.; Schaaf, A. van der; Tamboer, W.P.M.; Bakker, M.; Berden, J.H.M.; Dijkman, H.B.P.M.; Steenbergen, E.J.; Vlag, J. van der; Spriel, A.B. van
2010Expression of sialidase and dystroglycan in human glomerular diseases.Vogtlander, N.P.J.; Vlag, J. van der; Bakker, Maaike; Dijkman, H.B.; Wevers, R.A.; Campbell, K.P.; Wetzels, J.F.M.; Berden, J.H.M.
2010Lupus-derived monoclonal autoantibodies against apoptotic chromatin recognize acetylated conformational epitopes.Bavel, C.C.A.W. van; Dieker, J.W.C.; Tamboer, W.P.M.; Vlag, J. van der; Berden, J.H.M.
2010The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease.Smits, N.C.; Kurup, S.; Rops, A.L.; Dam, G.B. ten; Massuger, L.F.A.G.; Hafmans, T.G.M.; Turnbull, J.E.; Spillmann, D.; Li, J.P.; Kennel, S.J.; Wall, J.S.; Shworak, N.W.; Dekhuijzen, P.N.R.; Vlag, J. van der; Kuppevelt, A.H.M.S.M. van
2009Vascular endothelial growth factor in systemic capillary leak syndrome.Lesterhuis, W.J.; Rennings, A.J.M.; Leenders, W.P.J.; Nooteboom, A.; Punt, C.J.A.; Sweep, C.G.J.; Pickkers, P.; Geurts-Moespot, A.; Laarhoven, H.W.M. van; Vlag, J. van der; Berden, J.H.M.; Postma, C.T.; Meer, J.W.M. van der
2009The role of reactive oxygen species in apoptosis of the diabetic kidney.Wagener, F.A.D.T.G.; Dekker, D.; Berden, J.H.M.; Scharstuhl, A.; Vlag, J. van der
2009Both early and late apoptotic blebs are taken up by DC and induce IL-6 production.Fransen, J.H.; Hilbrands, L.B.; Jacobs, C.W.M.; Adema, G.J.; Berden, J.H.M.; Vlag, J. van der
2009Ligation of alpha-dystroglycan on podocytes induces intracellular signaling: a new mechanism for podocyte effacement?Vogtlander, N.P.J.; Visch, H.J.; Bakker, M.A.H.; Berden, J.H.M.; Vlag, J. van der
2009Role of the heparan sulfate proteoglycan syndecan-1 (CD138) in delayed-type hypersensitivity.Kharabi Masouleh, B.; Dam, G.B. ten; Wild, M.K.; Seelige, R.; Vlag, J. van der; Rops, L.W.M.; Echtermeyer, F.G.; Vestweber, D.; Kuppevelt, A.H.M.S.M. van; Kiesel, L.; Gotte, M.
2009Mutations of factor H impair regulation of surface-bound C3b by three mechanisms in atypical hemolytic uremic syndrome.Lehtinen, M.J.; Rops, L.W.M.; Isenman, D.E.; Vlag, J. van der; Jokiranta, T.S.
2009Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species.Hoven, M.J.W. van den; Waanders, F.; Rops, L.W.M.; Kramer, A.B.; Goor, H. van; Berden, J.H.M.; Navis, G.; Vlag, J. van der
2009Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies.Bavel, C.C.A.W. van; Dieker, J.W.C.; Muller, S.; Briand, J.P.; Monestier, M.; Berden, J.H.M.; Vlag, J. van der
2009Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17.Fransen, J.H.; Hilbrands, L.B.; Ruben, J.; Stoffels, M.; Adema, G.J.; Vlag, J. van der; Berden, J.H.M.
2009Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study.Manson, J.J.; Ma, A.; Rogers, P.; Mason, L.J.; Berden, J.H.M.; Vlag, J. van der; D'Cruz, D.P.; Isenberg, D.A.; Rahman, A.
2008Proteasome inhibition: a new therapeutic option in lupus nephritis?Vlag, J. van der; Berden, J.H.M.
2008Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus.Bavel, C.C.A.W. van; Fenton, K.A.; Rekvig, O.P.; Vlag, J. van der; Berden, J.H.M.
2008De rol van apoptose in de pathogenese van systemische lupus erythematosusVlag, J. van der; Berden, J.H.M.
2008Removal of heparan sulfate from the glomerular basement membrane blocks protein passage.Wijnhoven, T.J.M.; Lensen, J.F.M.; Wismans, R.G.; Lefeber, D.J.; Rops, A.; Vlag, J. van der; Berden, J.H.M.; Kuppevelt, A.H.M.S.M. van
2008Apoptosis in the pathogenesis of systemic lupus erythematosus.Munoz, L.E.; Bavel, C van; Franz, S.; Berden, J.H.M.; Herrmann, M.; Vlag, J. van der
2008Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria.Hoven, M.J.W. van den; Wijnhoven, T.J.; Li, J.P.; Zcharia, E.; Dijkman, H.B.; Wismans, P.G.P.; Rops, A.L.; Lensen, J.F.; Heuvel, L.P.v.d.; Kuppevelt, A.H.M.S.M. van; Vlodavsky, I.; Berden, J.H.M.; Vlag, J. van der
2008Sperm-derived histones contribute to zygotic chromatin in humans.Heijden, GW van der; Ramos, L.; Baart, E.B.; Berg, IM van den; Derijck, A.A.; Vlag, J. van der; Martini, E.; Boer, P. de
2008Heparan sulfate domains on cultured activated glomerular endothelial cells mediate leukocyte trafficking.Rops, A.L.; Hoven, M.J.W. van den; Baselmans, M.M.; Lensen, J.F.; Wijnhoven, T.J.; Heuvel, L.P.v.d.; Kuppevelt, A.H.M.S.M. van; Berden, J.H.M.; Vlag, J. van der
2008Characterization of anticoagulant heparinoids by immunoprofiling.Wijnhoven, T.J.M.; Westerlo, E.M.A. van de; Smits, N.C.; Lensen, J.F.M.; Rops, A.L.; Vlag, J. van der; Berden, J.H.M.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van
2008Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K.Dieker, J.; Cisterna, B.; Monneaux, F.; Decossas, M.; Vlag, J. van der; Biggiogera, M.; Muller, S.
2008Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null miceCunningham, R.; Esmaili, A.; Brown, E.; Biswas, R.S.; Murtazina, R.; Donowitz, M.; Dijkman, H.B.; Vlag, J. van der; Hogema, B.M.; Jonge, H.R. de; Shenolikar, S.; Wade, J.B.; Weinman, E.J.
2008Are primed polymorphonuclear leukocytes contributors to the high heparanase levels in hemodialysis patients?Cohen-Mazor, M.; Sela, S.; Mazor, R.; Ilan, N.; Vlodavsky, I.; Rops, A.L.; Vlag, J. van der; Cohen, H.I.; Kristal, B.
2008Heparanase induces a differential loss of heparan sulphate domains in overt diabetic nephropathy.Wijnhoven, T.J.; Hoven, M.J.W. van den; Ding, H.; Kuppevelt, A.H.M.S.M. van; Vlag, J. van der; Berden, J.H.M.; Prinz, R.A.; Lewis, E.J.; Schwartz, M.; Xu, X.
2008Incomplete nuclear transformation of human spermatozoa in oligo-astheno-teratospermia: characterization by indirect immunofluorescence of chromatin and thiol status.Ramos, L.; Heijden, GW van der; Derijck, A.; Berden, J.H.M.; Kremer, J.A.; Vlag, J. van der; Boer, P. de
2007Glomerular binding of anti-dsDNA autoantibodies: the dispute resolved?Bavel, C.C.A.W. van; Vlag, J. van der; Berden, J.H.M.
2007Anti-proteinuric effects of glycosaminoglycan-based drugs.Wijnhoven, T.J.M.; Lensen, J.F.M.; Rops, A.L.; McCarthy, K.J.; Vlag, J. van der; Berden, J.H.M.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van
2007Heparanase in glomerular diseases.Hoven, M.J.W. van den; Rops, A.L.; Vlodavsky, I.; Levidiotis, V.; Berden, J.H.M.; Vlag, J. van der
2007Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity.Harvey, S.J.; Jarad, G.; Cunningham, J.; Rops, A.L.; Vlag, J. van der; Berden, J.H.M.; Moeller, M.J.; Holzman, L.B.; Burgess, R.W.; Miner, J.H.
2007Removal of heparan sulfate from the glomerular basement membrane blocks protein passage.Wijnhoven, T.J.M.; Lensen, J.F.M.; Wismans, P.G.P.; Lefeber, D.J.; Rops, A.L.; Vlag, J. van der; Berden, J.H.M.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van
2007Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation.Heijden, G.W. van der; Derijck, A.H.A.; Posfai, E.; Giele, M.M.; Pelczar, P.; Ramos, L.; Wansink, D.G.; Vlag, J. van der; Peters, A.H.; Boer, P. de
2007Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes.Rops, A.L.; Jacobs, C.W.M.; Linssen, P.C.M.; Boezeman, J.B.M.; Lensen, J.F.M.; Wijnhoven, T.J.M.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van; Vlag, J. van der; Berden, J.H.M.
2007In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria.Wijnhoven, T.J.M.; Lensen, J.F.M.; Wismans, P.G.P.; Lamrani, M.; Monnens, L.A.H.; Wevers, R.A.; Rops, A.L.; Vlag, J. van der; Berden, J.H.M.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van
2007Syndecan-1 deficiency aggravates anti-glomerular basement membrane nephritis.Rops, A.L.; Gotte, M.; Baselmans, M.H.; Hoven, M.J.W. van den; Steenbergen, E.; Lensen, J.F.M.; Wijnhoven, T.J.M.; Cevikbas, F.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van; Berden, J.H.M.; Vlag, J. van der
2007Expression of glomerular heparan sulphate domains in murine and human lupus nephritis.Rops, A.L.; Hoven, M.J.W. van den; Bakker, M.A.H.; Lensen, J.F.M.; Wijnhoven, T.J.M.; Heuvel, L.P.W.J. van den; Kuppevelt, A.H.M.S.M. van; Vlag, J. van der; Berden, J.H.M.
2007A prospective study of anti-chromatin and anti-C1q autoantibodies in patients with proliferative lupus nephritis treated with cyclophosphamide pulses or azathioprine/methylprednisolone.Grootscholten, C.; Dieker, J.W.C.; McGrath, F.D.; Roos, A.; Derksen, R.H.W.M.; Vlag, J. van der; Daha, M.R.; Berden, J.H.M.

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