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| Full Text | Issue Date | Title | Author(s) |  | 2012 | T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization. | Koenders, M.I.; Marijnissen, R.J.; Joosten, L.A.B.; Abdollahi-Roodsaz, S.; Padova, F.E. Di; Loo, F.A.J. van de; Dulos, J.; Berg, W.B. van den; Boots, A.M.H. |
| | 2012 | Disease-dependent local IL-10 production ameliorates collagen induced arthritis in mice | Henningsson, L.; Eneljung, T.; Jirholt, P.; Tengvall, S.; Lidberg, U.; van den Berg, W.B.; van de Loo, F.A.; Gjertsson, I. |
| | 2012 | Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice. | Abdollahi-Roodsaz, S.; Loo, F.A.J. van de; Koenders, M.I.; Helsen, M.M.A.; Walgreen, B.; Bersselaar, L.A.M. van den; Arntz, O.J.; Takahashi, N.; Joosten, L.A.B.; Berg, W.B. van den |
| | 2012 | Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte function | van de Loo, F.A.; Veenbergen, S.; van den Brand, B.; Bennink, M.B.; Blaney-Davidson, E.; Arntz, O.J.; van Beuningen, H.M.; van der Kraan, P.M.; van den Berg, W.B. |
 | 2011 | Trapped in a vicious loop: Toll-like receptors sustain the spontaneous cytokine production by rheumatoid synovium | Abdollahi-Roodsaz, S.; Loo, F.A. van de; Berg, W.B. van den |
| | 2011 | Soluble IL-18 receptor complex: a new star in the firmament of rheumatoid arthritis diagnosis? | Loo, F.A.J. van de |
| | 2011 | Toll-like receptor 4 signalling is specifically TGF-beta-activated kinase 1 independent in synovial fibroblasts | Geurts, J.; van den Brand, B.T.; Wolf, A.; Abdollahi-Roodsaz, S.; Arntz, O.J.; Kracht, M.; van den Berg, W.B.; van de Loo, F.A. |
| | 2011 | A pivotal role for antigen-presenting cells overexpressing SOCS3 in controlling invariant NKT cell responses during collagen-induced arthritis | Veenbergen, S.; Bennink, M.B.; Affandi, A.J.; Bessis, N.; Biton, J.; Arntz, O.J.; Berg, W.B. van den; Loo, F.A. van de |
| | 2011 | A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts | Geurts, J.; Vermeij, E.A.; Pohlers, D.; Arntz, O.J.; Kinne, R.W.; Berg, W.B. van den; Loo, F.A. van de |
 | 2011 | Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis | Heinhuis, B.; Koenders, M.M.J.F.; Loo, F.A.J. van de; Netea, M.G.; Berg, W.B. van den; Joosten, L.A.B. |
| | 2011 | Abnormal actomyosin assembly in proliferating and differentiating myoblasts upon expression of a cytosolic DMPK isoform | Mulders, S.A.M.; Horssen, R. van; Gerrits, L.; Bennink, M.B.; Pluk, W.L.L.P.; Boer-van Huizen, R.T. de; Croes, H.J.E.; Wijers, M.J.P.; Loo, F.A. van de; Fransen, J.; Wieringa, B.; Wansink, D.G. |
| | 2011 | Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade | Heinhuis, B.; Koenders, M.M.J.F.; Riel, P.L.C.M. van; Loo, F.A.J. van de; Dinarello, C.A.; Netea, M.G.; Berg, W.B. van den; Joosten, L.A.B. |
| | 2011 | Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1beta, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritis | Koenders, M.I.; Marijnissen, R.J.; Devesa, I.; Lubberts, E.; Joosten, L.A.B.; Roth, J.; Lent, P.L.E.M. van; Loo, F.A.J. van de; Berg, W.B. van den |
| | 2010 | IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2. | Heinhuis, B.; Koenders, M.M.J.F.; Loo, F.A.J. van de; Lent, P.L.E.M. van; Kim, S.H.; Dinarello, C.A.; Joosten, L.A.B.; Berg, W.B. van den |
| | 2010 | The natural soluble form of IL-18 receptor beta exacerbates collagen-induced arthritis via modulation of T-cell immune responses. | Veenbergen, S.; Smeets, R.L.; Bennink, M.B.; Arntz, O.J.; Joosten, L.A.B.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2010 | A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis. | Arntz, O.J.; Geurts, J.; Veenbergen, S.; Bennink, M.B.; Brand, B.T. van den; Abdollahi-Roodsaz, S.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2009 | Immunocytokines: the long awaited therapeutic magic bullet in rheumatoid arthritis? | Loo, F.A.J. van de; Berg, W.B. van den |
| | 2009 | Computational design and application of endogenous promoters for transcriptionally targeted gene therapy for rheumatoid arthritis. | Geurts, J.; Joosten, L.A.B.; Takahashi, N.; Arntz, O.J.; Gluck, A.; Bennink, M.B.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2009 | A tail-anchored myotonic dystrophy protein kinase isoform induces perinuclear clustering of mitochondria, autophagy, and apoptosis. | Oude Ophuis, R.J.A.; Wijers-Rouw, M.J.P.; Bennink, M.B.; Loo, F.A.J. van de; Fransen, J.; Wieringa, B.; Wansink, D.G. |
| | 2009 | Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation. | Abdollahi-Roodsaz, S.; Joosten, L.A.B.; Koenders, M.I.; Brand, B.T. van den; Loo, F.A.J. van de; Berg, W.B. van den |
| | 2009 | Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1. | Blom, A.B.; Brockbank, S.M.; Lent, P.L.E.M. van; Beuningen, H.M. van; Geurts, J.; Takahashi, N.; Kraan, P.M. van der; Loo, F.A.J. van de; Schreurs, B.W.; Clements, K.; Newham, P.; Berg, W.B. van den |
| | 2008 | Targeting growth factors in arthritis : A rational for restoring the IGF-1 respose in chondrocytes | Loo, F.A.J. van de; Veenbergen, S.; Berg, W.B. van den |
| | 2008 | Tumor marker nucleoporin 88 kDa regulates nucleocytoplasmic transport of NF-kappaB. | Takahashi, N.; Kilsdonk, J.W.J. van; Ostendorf, B.; Smeets, R.; Bruggeman, S.W.M.; Alonso, A.; Loo, F.A.J. van de; Schneider, M.; Berg, W.B. van den; Swart, G.W.M. |
| | 2008 | Tumor marker nucleoporin 88 kDa regulates nucleocytoplasmic transport of NF-kappaB. | Takahashi, N.; Kilsdonk, J.W.J. van; Ostendorf, B.; Smeets, R.; Bruggeman, S.W.M.; Alonso, A.; Loo, F.A.J. van de; Schneider, M.; Berg, W.B. van den; Swart, G.W. |
| | 2008 | Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis. | Veenbergen, S.; Bennink, M.B.; Hooge, A.S.K. de; Arntz, O.J.; Smeets, R.L.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2008 | Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis. | Lent, P.L.E.M. van; Grevers, L.C.; Blom, A.B.; Arntz, O.J.; Loo, F.A.J. van de; Kraan, P.M. van der; Abdollahi-Roodsaz, S.; Srikrishna, G.; Freeze, H.; Sloetjes, A.; Nacken, W.; Vogl, T.; Roth, J.; Berg, W.B. van den |
| | 2008 | Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice : a comparative study using anti-TNFalpha, anti-IL-1alpha/beta and IL-1Ra | Joosten, L.A.B.; Helsen, M.M.A.; Loo, F.A.J. van de; Berg, W.B. van den |
| | 2007 | Application of a disease-regulated promoter is a safer mode of local IL-4 gene therapy for arthritis. | Geurts, J.; Arntz, O.J.; Bennink, M.B.; Joosten, L.A.B.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2007 | Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation. | Blaney Davidson, E.N.; Vitters, E.L.; Beuningen, H.M. van; Loo, F.A.J. van de; Berg, W.B. van den; Kraan, P.M. van der |
| | 2007 | Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling. | Blaney Davidson, E.N.; Vitters, E.L.; Lent, P.L.E.M. van; Loo, F.A.J. van de; Berg, W.B. van den; Kraan, P.M. van der |
| | 2006 | Gene therapy works in animal models of rheumatoid arthritis...so what! | Loo, F.A.J. van de; Geurts, J.; Berg, W.B. van den |
| | 2006 | Interleukin-17 acts independently of TNF-alpha under arthritic conditions. | Koenders, M.I.; Lubberts, E.; Loo, F.A.J. van de; Oppers-Walgreen, B.; Bersselaar, L.A.M. van den; Helsen, M.M.A.; Kolls, J.; Padova, F.E. Di; Joosten, L.A.B.; Berg, W.B. van den |
| | 2006 | Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. | Netea, M.G.; Joosten, L.A.B.; Lewis, E.; Jensen, D.R.; Voshol, P.J.; Kullberg, B.J.; Tack, C.J.J.; Krieken, H. van; Kim, S.H.; Stalenhoef, A.F.H.; Loo, F.A.J. van de; Verschueren, I.; Pulawa, L.; Akira, S.; Eckel, R.H.; Dinarello, C.A.; Berg, W.B. van den; Meer, J.W.M. van der |
| | 2006 | A novel role for suppressor of cytokine signaling 3 in cartilage destruction via induction of chondrocyte desensitization toward insulin-like growth factor. | Smeets, R.L.L.; Veenbergen, S.; Arntz, O.J.; Bennink, M.B.; Joosten, L.A.B.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2006 | IL-32, a proinflammatory cytokine in rheumatoid arthritis. | Joosten, L.A.B.; Netea, M.G.; Kim, S.H.; Yoon, D.Y.; Oppers-Walgreen, B.; Radstake, T.R.D.J.; Barrera, P.; Loo, F.A.J. van de; Dinarello, C.A.; Berg, W.B. van den |
| | 2005 | Divergent mitochondrial and endoplasmic reticulum association of DMPK splice isoforms depends on unique sequence arrangements in tail anchors. | Herpen, R.E.M.A. van; Oude Ophuis, R.J.A.; Wijers-Rouw, M.J.P.; Bennink, M.B.; Loo, F.A.J. van de; Fransen, J.; Wieringa, B.; Wansink, D.G. |
| | 2005 | Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging. | Hooge, A.S.K. de; Loo, F.A.J. van de; Bennink, M.B.; Arntz, O.J.; Hooge, P. de; Berg, W.B. van den |
| | 2005 | Enhancement of adenovirus-mediated gene delivery to rheumatoid arthritis synoviocytes and synovium by fiber modifications: role of arginine-glycine-aspartic acid (RGD)- and non-RGD-binding integrins. | Toh, M.L.; Hong, S.S.; Loo, F.A.J. van de; Franqueville, L.; Lindholm, L.; Berg, W.B. van den; Boulanger, P.; Miossec, P. |
| | 2005 | Soluble interleukin-1 receptor accessory protein ameliorates collagen-induced arthritis by a different mode of action from that of interleukin-1 receptor antagonist. | Smeets, R.L.L.; Joosten, L.A.B.; Arntz, O.J.; Bennink, M.B.; Takahashi, N.; Carlsen, H.; Martin, M.U.; Berg, W.B. van den; Loo, F.A.J. van de |
| | 2005 | NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis. | Lent, P.L.E.M. van; Nabbe, K.C.A.M.; Blom, A.B.; Sloetjes, A.W.; Holthuysen, A.E.M.; Kolls, J.; Loo, F.A.J. van de; Holland, S.M.; Berg, W.B. van den |
| | 2004 | Role of gene therapy in tissue engineering procedures in rheumatology: the use of animal models. | Kraan, P.M. van der; Loo, F.A.J. van de; Berg, W.B. van den |
| | 2004 | Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients? | Loo, F.A.J. van de; Smeets, R.L.L.; Berg, W.B. van den |
| | 2004 | Inflammation-responsive promoters for fine-tuned gene therapy in rheumatoid arthritis. | Loo, F.A.J. van de |
| | 2004 | An inflammation-inducible adenoviral expression system for local treatment of the arthritic joint. | Loo, F.A.J. van de; Hooge, A.S.K. de; Smeets, R.L.L.; Bakker, A.C.; Bennink, M.B.; Arntz, O.J.; Joosten, L.A.B.; Beuningen, H.M. van; Kraan, P.M. van der; Varley, A.W.; Berg, W.B. van den |
| | 2004 | Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. | Hooge, A.S.K. de; Loo, F.A.J. van de; Koenders, M.I.; Bennink, M.B.; Arntz, O.J.; Kolbe, T.; Berg, W.B. van den |
| | 2004 | Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction. | Joosten, L.A.B.; Smeets, R.L.L.; Koenders, M.I.; Bersselaar, L.A.M. van den; Helsen, M.M.A.; Oppers-Walgreen, B.; Lubberts, E.; Iwakura, Y.; Loo, F.A.J. van de; Berg, W.B. van den |
| | 2000 | An IFN-gamma-independent proinflammatory role of IL-18 in murine streptococcal cell wall arthritis | Joosten, L.A.B.; Loo, F.A.J. van de; Lubberts, E.; Helsen, M.M.A.; Netea, M.G.; Meer, J.W.M. van der; Dinarello, C.A.; Berg, W.B. van den |
| | 1997 | Interleukin-6 reduces cartilage destruction during experimental arthritis : A study in Interleukin-6-deficient mice | Loo, F.A.J. van de; Kuiper, S.; Enckevort, F.H.J. van; Arntz, O.J.; Berg, W.B. van den |
| | 1997 | Interleukin-6 reduces cartilage destruction during experimental arthritis : A study in interleukin-6-deficient mice | Loo, F.A.J. van de; Kuiper, S.; Enckevort, F.H.J. van; Arntz, O.J.; Berg, W.B. van den |
| | 1997 | Effect of interleukin 1 and leukaemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: Role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis | Loo, F.A.J. van de; Arntz, O.J.; Berg, W.B. van den |
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