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Full TextIssue DateTitleAuthor(s)
2011In vivo watermanagement: van verzilten tot verzuipenDeen, P.M.T.
2011Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover studyRennings, A.J.M.; Russel, F.G.M.; Li, Y.; Deen, P.M.T.; Masereeuw, R.; Tack, C.J.J.; Smits, P.
2011The physiological implication of novel proteins in systemic osmoregulationSinke, A.P.; Deen, P.M.T.
2011Succinate receptors in the kidneyDeen, P.M.T.; Robben, J.H.
2011Counteracting vasopressin-mediated water reabsorption by ATP, dopamine, and phorbol esters: mechanisms of actionBoone, M.; Kortenoeven, M.L.A.; Robben, J.H.; Tamma, G.; Deen, P.M.T.
2011Novel mutation in the AVPR2 gene in a Danish male with nephrogenic diabetes insipidus caused by ER retention and subsequent lysosomal degradation of the mutant receptorNejsum, L.N.; Christensen, T.M.; Robben, J.H.; Milligan, G.; Deen, P.M.T.; Bichet, D.G.; Levin, K.
2011alphaENaC-mediated lithium absorption promotes nephrogenic diabetes insipidusChristensen, B.M.; Zuber, A.M.; Loffing, J.; Stehle, J.C.; Deen, P.M.T.; Rossier, B.C.; Hummler, E.
2011Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulationSinke, A.P.; Caputo, C.; Tsaih, S.W.; Yuan, R.; Ren, D.; Deen, P.M.T.; Korstanje, R.
2011Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitinationTamma, G.; Robben, J.H.; Trimpert, C.; Boone, M.; Deen, P.M.T.
2011Hypotonicity-induced reduction of aquaporin-2 transcription in mpkCCD cells is independent of the tonicity responsive element, vasopressin, and cAMPKortenoeven, M.L.A.; Brand, M. van den; Wetzels, J.F.M.; Deen, P.M.T.
2011Autosomal recessive mental retardation, deafness, ankylosis, and mild hypophosphatemia associated with a novel ANKH mutation in a consanguineous familyMorava, E.; Kuhnisch, J.; Drijvers, J.M.; Robben, J.H.; Cremers, C.W.R.J.; Setten, P. van; Branten, A.J.W.; Stumpp, S.; Jong, A. de; Voesenek, K.E.J.; Vermeer, S.; Heister, A.; Claahsen-van der Grinten, H.L.; O'Neill, C.W.; Willemsen, M.H.; Lefeber, D.J.; Deen, P.M.T.; Kornak, U.; Kremer, J.M.J.; Wevers, R.A.
2010A system biology approach : modeling of Aquaporin-2 trafficking : WSPC proceedingsFrohlich, M.A.; Deen, P.M.T.; Klipp, E.
2010Potential of nonpeptide (ant)agonists to rescue vasopressin V2 receptor mutants for the treatment of X-linked nephrogenic diabetes insipidus.Los, E.L.; Deen, P.M.T.; Robben, J.H.
2010Blockade of dopamine, but not noradrenaline, transporters produces hyperthermia in rats that lack serotonin transporters.Olivier, J.D.A.; Cools, A.R.; Deen, P.M.T.; Olivier, B.; Ellenbroek, A.A.
2010RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter.Ko, B.; Kamsteeg, E.J.; Cooke, L.L.; Moddes, L.N.; Deen, P.M.T.; Hoover, R.S.
2010The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.Boone, M.; Mobasheri, A.; Fenton, R.A.; Balkom, B.W.M. van; Wismans, R.; Zee, C.E.E.M. van der; Deen, P.M.T.
2010Effect of the cGMP pathway on AQP2 expression and translocation: potential implications for nephrogenic diabetes insipidus.Boone, M.; Kortenoeven, M.L.A.; Robben, J.H.; Deen, P.M.T.
2010Functional variation in the arginine vasopressin 2 receptor as a modifier of human plasma von Willebrand factor levels.Nossent, A.Y.; Robben, J.H.; Deen, P.M.T.; Vos, H.L.; Rosendaal, F.R.; Doggen, C.J.; Hansen, J.L.; Sheikh, S.P.; Bertina, R.M.; Eikenboom, J.C.
2009EUNEFRON, the European Network for the Study of Orphan Nephropathies.Devuyst, O.; Meij, I.; Jeunemaitre, X.; Ronco, P.; Antignac, C.; Christensen, E.I.; Slobbe-Knoers, V.V.A.M.; Levtchenko, E.N.; Deen, P.M.T.; Muller, D.; Wagner, C.A.; Rampoldi, L.; Hoff, W.G. van 't
2009LIP5 interacts with aquaporin 2 and facilitates its lysosomal degradationBalkom, B.W.M. van; Boone, M.; Hendriks, G.; Kamsteeg, E.J.; Robben, J.H.; Stronks, H.C.; Voorde, A. van der; Herp, F. van; Sluijs, P. van der; Deen, P.M.T.
2009Congenital nephrogenic diabetes insipidus: what can we learn from mouse models?Boone, M.; Deen, P.M.T.
2009Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells.Robben, J.H.; Fenton, R.A.; Vargas, S.L.; Schweer, H.; Peti-Peterdi, J.; Deen, P.M.T.; Milligan, G.
2009Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus.Kortenoeven, M.L.A.; Li, Y.; Shaw, S.M.; Gaeggeler, H.P.; Rossier, B.C.; Wetzels, J.F.M.; Deen, P.M.T.
2009Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists.Robben, J.H.; Kortenoeven, M.L.A.; Sze, M.; Yae, C.; Milligan, G.; Oorschot, V.M.; Klumperman, J.; Knoers, N.V.A.M.; Deen, P.M.T.
2009p.R254Q mutation in the aquaporin-2 water channel causing dominant nephrogenic diabetes insipidus is due to a lack of arginine vasopressin-induced phosphorylation.Savelkoul, P.J.M.; Mattia, F.P. de; Li, Y.; Kamsteeg, E.J.; Konings, I.B.M.; Sluijs, P. van der; Deen, P.M.T.
2009LIP5 interacts with aquaporin 2 and facilitates its lysosomal degradation.Balkom, B.W.M. van; Boone, M.; Hendriks, G.; Kamsteeg, E.J.; Robben, J.H.; Stronks, H.C.; Voorde, A. van der; Herp, F. van; Sluijs, P. van der; Deen, P.M.T.
2009Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.Wildman, S.S.; Boone, M.; Peppiatt-Wildman, C.M.; Contreras-Sanz, A.; King, B.F.; Shirley, D.G.; Deen, P.M.T.; Unwin, R.J.
2009Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus.Kamsteeg, E.J.; Stoffels, M.; Tamma, G.; Siemerink-Konings, I.B.M.; Deen, P.M.T.
2009SLC29A3 gene is mutated in pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway.Cliffe, S.T.; Kramer, J.M.; Hussain, K.; Robben, J.H.; Jong, E.K. de; Brouwer, A.P.M. de; Nibbeling, E.; Kamsteeg, E.J.; Wong, M.; Prendiville, J.; James, C.; Padidela, R.; Becknell, C.; Bokhoven, J.H.L.M. van; Deen, P.M.T.; Hennekam, R.C.M.; Lindeman, R.; Schenck, A.; Roscioli, T.; Buckley, M.F.
2008Aquaporin 2 mutations in nephrogenic diabetes insipidus.Loonen, A.J.M.; Knoers, N.V.A.M.; Os, C.H. van; Deen, P.M.T.
2008Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption.Boone, M.; Deen, P.M.T.
2008Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2Li, Y.; Konings, I.B.M.; Zhao, J.; Price, L.S.; Heer, E. de; Deen, P.M.T.
2008Acute tryptophan depletion dose dependently impairs object memory in serotonin transporter knockout rats.Olivier, J.D.A.; Jans, L.A.; Korte-Bouws, G.A.; Korte, S.M.; Deen, P.M.T.; Cools, A.R.; Ellenbroek, B.A.; Blokland, A.
2008Missorting of the Aquaporin-2 mutant E258K to multivesicular bodies/lysosomes in dominant NDI is associated with its monoubiquitination and increased phosphorylation by PKC but is due to the loss of E258.Kamsteeg, E.J.; Savelkoul, P.J.; Hendriks, G.; Konings, I.B.M.; Nivillac, N.M.; Lagendijk, A.K.; Sluijs, P van der; Deen, P.M.T.
2008A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders.Olivier, J.D.A.; Hart, MG Van Der; Swelm, R.P.L. van; Dederen, P.J.W.C.; Homberg, J.R.; Cremers, T.; Deen, P.M.T.; Cuppen, E.; Cools, A.R.; Ellenbroek, B.A.
2007Pharmacological chaperones in nephrogenic diabetes insipidus: possibilities for clinical application.Robben, J.H.; Deen, P.M.T.
2007Functional rescue of vasopressin V2 receptor mutants in MDCK cells by pharmacochaperones : relevance to therapy of nephrogenic diabetes insipidusRobben, J.H.; Sze, M.; Knoers, N.V.A.M.; Deen, P.M.T.
2007Relief of nocturnal enuresis by desmopressin is kidney and vasopressin type 2 receptor independent.Robben, J.H.; Sze, M.; Knoers, N.V.A.M.; Eggert, P.; Deen, P.M.T.; Muller, D.
2007MAL decreases the internalization of the aquaporin-2 water channel.Kamsteeg, E.J.; Duffield, A.S.; Konings, I.B.M.; Spencer, J.; Pagel, P.; Deen, P.M.T.; Caplan, M.J.
2007Water in health and disease: new aspects of disturbances in water metabolism.Peters, H.P.E.; Robben, J.H.; Deen, P.M.T.; Wetzels, J.F.M.
2006Introduction: special issue on aquaporins.Chaumont, F.; Deen, P.M.T.; Delporte, C.; Devuyst, O.; Flamion, B.; Lameire, N.H.; Steels, P.; Verbavatz, J.M.
2006Aquaporines in de nier en hun rol in nefrogene diabetes insipidusRobben, J.H.; Knoers, N.V.A.M.; Deen, P.M.T.
2006Yolk proteolysis and aquaporin-1o play essential roles to regulate fish oocyte hydration during meiosis resumption.Fabra, M.; Raldua, D.; Bozzo, M.G.; Deen, P.M.T.; Lubzens, E.; Cerda, J.
2006Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.Robben, J.H.; Sze, M.; Knoers, N.V.A.M.; Deen, P.M.T.
2006Cell biological aspects of the vasopressin type-2 receptor and aquaporin 2 water channel in nephrogenic diabetes insipidus.Robben, J.H.; Knoers, N.V.A.M.; Deen, P.M.T.
2006Polarisation, key to good localisation.Beest, M. van; Robben, J.H.; Savelkoul, P.J.M.; Hendriks, G.; Devonald, M.A.; Konings, I.B.M.; Lagendijk, A.K.; Karet, F.; Deen, P.M.T.
2006Lys63-linked short-chain ubiquitination regulates aquaporin-2 endocytosis from the apical membrane.Kamsteeg, E.J.; Hendriks, G.; Boone, M.; Konings, I.B.M.; Oorschot, V.; Sluijs, P. van der; Klumperman, J.; Deen, P.M.T.
2006Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action.Detmers, F.J.M.; Groot, B.L. de; Muller, E.M.; Hinton, A.; Konings, I.B.M.; Sze, M.; Flitsch, S.L.; Grubmuller, H.; Deen, P.M.T.
2006Development of lithium-induced nephrogenic diabetes insipidus is dissociated from adenylyl cyclase activity.Li, Y.; Shaw, S.M.; Kamsteeg, E.J.; Walle, A. van de; Deen, P.M.T.
2005Marine fish egg hydration is aquaporin-mediated.Fabra, M.; Raldua, D.; Power, D.M.; Deen, P.M.T.; Cerda, J.

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