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| Full Text | Issue Date | Title | Author(s) |  | 2011 | Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritis | Hofkens, W.; Grevers, L.C.; Walgreen, B.; Vries, T.J. de; Leenen, P.J.M.; Everts, V.; Storm, G.; Berg, W.B. van den; Lent, P.L. van |
| | 2011 | Liposomal targeting of glucocorticoids to the inflamed synovium inhibits cartilage matrix destruction during murine antigen-induced arthritis | Hofkens, W.; Storm, G.; van den Berg, W.B.; van Lent, P.L. |
| | 2011 | S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll-like receptor 4: implications for bone destruction in murine antigen-induced arthritis | Grevers, L.C.; Vries, T.J. de; Vogl, T.; Abdollahi-Roodsaz, S.; Sloetjes, A.W.; Leenen, P.J.M.; Roth, J.; Everts, V.; van den Berg, W.B.; van Lent, P.L. |
| | 2011 | Cytosolic phospholipase A2alpha gene silencing in the myeloid lineage alters development of Th1 responses and reduces disease severity in collagen-induced arthritis | Courties, G.; Baron, M.; Presumey, J.; Escriou, V.; Lent, P.L.E.M. van; Scherman, D.; Cantagrel, A.; Berg, W.B. van den; Jorgensen, C.; Apparailly, F.; Davignon, J.L. |
 | 2011 | Safety of glucocorticoids can be improved by lower yet still effective dosages of liposomal steroid formulations in murine antigen-induced arthritis: comparison of prednisolone with budesonide | Hofkens, W.; Hoven, J.M. van den; Pesman, G.J.; Nabbe, K.C.A.M.; Sweep, F.C.; Storm, G.; Berg, W.B. van den; Lent, P.L. van |
| | 2011 | Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Kruppel-like factor 2 | Tits, L.J.H. van; Stienstra, R.; Lent, P.L.E.M. van; Netea, M.G.; Joosten, L.A.B.; Stalenhoef, A.F.H. |
| | 2011 | Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1beta, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritis | Koenders, M.I.; Marijnissen, R.J.; Devesa, I.; Lubberts, E.; Joosten, L.A.B.; Roth, J.; Lent, P.L.E.M. van; Loo, F.A.J. van de; Berg, W.B. van den |
| | 2010 | To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy. | Blom, A.B.; Lent, P.L.E.M. van; Kraan, P.M. van der; Berg, W.B. van den |
| | 2010 | IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2. | Heinhuis, B.; Koenders, M.M.J.F.; Loo, F.A.J. van de; Lent, P.L.E.M. van; Kim, S.H.; Dinarello, C.A.; Joosten, L.A.B.; Berg, W.B. van den |
| | 2010 | S100A8 causes a shift toward expression of activatory Fcgamma receptors on macrophages via toll-like receptor 4 and regulates Fcgamma receptor expression in synovium during chronic experimental arthritis. | Lent, P.L.E.M. van; Grevers, L.C.; Schelbergen, R.F.P.; Blom, A.B.; Geurts, J.; Sloetjes, A.W.; Vogl, T.; Roth, J.; Berg, W.B. van den |
| | 2009 | Selectively induced death of macrophages in the synovial lining of murine knee joints using (10)B-liposomes and boron neutron capture synovectomy. | Lent, P.L.E.M. van; Krijger, G.C.; Hofkens, W.; Nievaart, V.A.; Sloetjes, A.W.; Moss, R.L.; Koning, G.A.; Berg, W.B. van den |
| | 2009 | Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1. | Blom, A.B.; Brockbank, S.M.; Lent, P.L.E.M. van; Beuningen, H.M. van; Geurts, J.; Takahashi, N.; Kraan, P.M. van der; Loo, F.A.J. van de; Schreurs, B.W.; Clements, K.; Newham, P.; Berg, W.B. van den |
| | 2009 | Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis. | Grevers, L.C.; Lent, P.L.E.M. van; Koenders, M.I.; Walgreen, B.; Sloetjes, A.W.; Nimmerjahn, F.; Verbeek, J.S.; Berg, W.B. van den |
| | 2009 | Scavenger receptor class A type I/II determines matrix metalloproteinase-mediated cartilage destruction and chondrocyte death in antigen-induced arthritis. | Lent, P.L.E.M. van; Hofkens, W.; Blom, A.B.; Grevers, L.C.; Sloetjes, A.W.; Takahashi, N.; Tits, L.J.H. van; Vogl, T.; Roth, J.; Winther, M.P. de; Berg, W.B. van den |
| | 2008 | Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis. | Lent, P.L.E.M. van; Grevers, L.; Blom, A.B.; Sloetjes, A.; Mort, J.S.; Vogl, T.; Nacken, W.; Berg, W.B. van den; Roth, J. |
| | 2008 | Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII. | Boross, P.; Lent, P.L.E.M. van; Martin-Ramirez, J.; Kaa, J. van der; Mulder, M.H.; Claassens, J.W.; Berg, W.B. van den; Arandhara, V.L.; Verbeek, J.S. |
| | 2008 | Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production. | Abdollahi-Roodsaz, S.; Joosten, L.A.B.; Helsen, M.M.A.; Walgreen, B.; Lent, P.L.E.M. van; Bersselaar, L.A.M. van den; Koenders, Mieke; Berg, W.B. van den |
| | 2008 | Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis. | Lent, P.L.E.M. van; Grevers, L.C.; Blom, A.B.; Arntz, O.J.; Loo, F.A.J. van de; Kraan, P.M. van der; Abdollahi-Roodsaz, S.; Srikrishna, G.; Freeze, H.; Sloetjes, A.; Nacken, W.; Vogl, T.; Roth, J.; Berg, W.B. van den |
| | 2007 | Murine antigen-induced arthritis. | Berg, W.B. van den; Joosten, L.A.B.; Lent, P.L.E.M. van |
| | 2007 | Amplifying elements of arthritis and joint destruction | Berg, W.B. van den; Lent, P.L.E.M. van; Joosten, L.A.B.; Abdollahi-Roodsaz, S.; Koenders, M.I. |
| | 2007 | Toll-like receptor 4 induced FcgammaR expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis: Toll-like receptor 4 largely regulates FcgammaR expression by interleukin 10. | Lent, P.L.E.M. van; Blom, A.B.; Grevers, L.C.; Sloetjes, A.W.; Berg, W.B. van den |
| | 2007 | Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3. | Blom, A.B.; Lent, P.L.E.M. van; Libregts, S.; Holthuysen, A.E.M.; Kraan, P.M. van der; Rooijen, N. van; Berg, W.B. van den |
| | 2007 | Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling. | Blaney Davidson, E.N.; Vitters, E.L.; Lent, P.L.E.M. van; Loo, F.A.J. van de; Berg, W.B. van den; Kraan, P.M. van der |
| | 2006 | Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation. | Lent, P.L.E.M. van; Grevers, L.C.; Lubberts, E.; Vries, T.J. de; Nabbe, K.C.A.M.; Verbeek, S.; Oppers-Walgreen, B.; Sloetjes, A.W.; Blom, A.B.; Berg, W.B. van den |
| | 2005 | Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of Fc gamma RII expression, which has clear functional consequences. | Radstake, T.R.D.J.; Nabbe, K.C.A.M.; Wenink, M.H.; Roelofs, M.F.; Oosterlaar, A.; Lieshout, A.W.T. van; Barrera Rico, P.; Lent, P.L.E.M. van; Berg, W.B. van den |
| | 2005 | Joint inflammation and chondrocyte death become independent of Fcgamma receptor type III by local overexpression of interferon-gamma during immune complex-mediated arthritis. | Nabbe, K.C.A.M.; Boross, P.; Holthuysen, A.E.M.; Sloetjes, A.W.; Kolls, J.; Verbeek, S.; Lent, P.L.E.M. van; Berg, W.B. van den |
 | 2005 | Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation. | Nabbe, K.C.A.M.; Lent, P.L.E.M. van; Holthuysen, A.E.M.; Sloetjes, A.W.; Koch, A.E.; Radstake, T.R.D.J.; Berg, W.B. van den |
| | 2005 | Expression and localisation of the new metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed synovial membranes of patients with rheumatoid arthritis. | Lent, P.L.E.M. van; Span, P.N.; Sloetjes, A.W.; Radstake, T.R.D.J.; Lieshout, A.W.T. van; Heuvel, J.J.T.M.; Sweep, C.G.J.; Berg, W.B. van den |
| | 2005 | NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis. | Lent, P.L.E.M. van; Nabbe, K.C.A.M.; Blom, A.B.; Sloetjes, A.W.; Holthuysen, A.E.M.; Kolls, J.; Loo, F.A.J. van de; Holland, S.M.; Berg, W.B. van den |
| | 2004 | Increased expression of Fcgamma R II and III on macrophages of rheumatoid arthritis patients results in higher production of TNF alpha and matrix metalloproteinase : Reply | Radstake, T.R.D.J.; Blom, A.B.; Lent, P.L.E.M. van; Berg, W.B. van den |
| | 2004 | Reply (Increased expression of Fc gamma RII and III on macrophages of rheumatoid arthritis patients result in higher production of TNF alpha and matrix metalloproteinase) | Radstake, T.R.D.J.; Blom, A.B.; Lent, P.L.E.M. van; Berg, W.B. van den |
| | 2004 | Expression of the novel metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed membranes of rheumatoid arthritis patients : cytoplasmatic but not membrane bound expression of RECK in synovial macrophages | Lent, P.L.E.M. van; Span, P.N.; Sloetjes, A.W.; Radstake, T.R.D.J.; Lieshout, A.W.T. van; Heuvel, J.J.T.M.; Sweep, C.G.J.; Berg, W.B. van den |
| | 2004 | Increased Fc gamma RII expression and aberrant tumour necrosis factor a production by mature dendritic cells from patients with active rheumatoid arthritis | Radstake, T.R.D.J.; Blom, A.B.; Slöetjes, A. W.; Gorselen, E.O.F. van; Pesman, G.J.; Engelen, L.P.H.; Torensma, R.; Berg, W.B. van den; Figdor, C.G.; Lent, P.L.E.M. van; Adema, G.J.; Barrera, P. |
| | 2004 | Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis. | Blom, A.B.; Lent, P.L.E.M. van; Holthuysen, A.E.M.; Kraan, P.M. van der; Roth, J.; Rooijen, N. van; Berg, W.B. van den |
| | 2004 | Increased FcgammaRII expression and aberrant tumour necrosis factor alpha production by mature dendritic cells from patients with active rheumatoid arthritis. | Radstake, T.R.D.J.; Blom, A.B.; Sloetjes, A.W.; Gorselen, E.O. van; Pesman, G.J.; Engelen, L.P.; Torensma, R.; Berg, W.B. van den; Figdor, C.G.; Lent, P.L.E.M. van; Adema, G.J.; Barrera Rico, P. |
| | 2004 | Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. | Lent, P.L.E.M. van; Blom, A.B.; Kraan, P.M. van der; Holthuysen, A.E.M.; Vitters, E.L.; Rooijen, N. van; Smeets, R.L.L.; Nabbe, K.C.A.M.; Berg, W.B. van den |
| | 2004 | Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis. | Metselaar, J.M.; Berg, W.B. van den; Holthuysen, A.E.M.; Wauben, M.H.M.; Storm, G.; Lent, P.L.E.M. van |
| | 2004 | High production of proinflammatory and Th1 cytokines by dendritic cells from patients with rheumatoid arthritis, and down regulation upon FcgammaR triggering. | Radstake, T.R.D.J.; Lent, P.L.E.M. van; Pesman, G.J.; Blom, A.B.; Sweep, C.G.J.; Ronnelid, J.; Adema, G.J.; Barrera Rico, P.; Berg, W.B. van den |
| | 2003 | Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with intercellular adhesion molecule 3-positive T cells | Lent, P.L.E.M. van; Figdor, C.G.; Barrera, P.; Ginkel, K. van; Sloetjes, A.; Berg, W.B. van den; Torensma, R. |
| | 2002 | Increased TNF-alfa production by dendritic cells (DC) in rheumatoid arthritis (RA) | Radstake, T.R.D.J.; Blom, A.B.; Pesman, G.J.; Figdor, C.G.; Berg, W.B. van den; Adema, G.J.; Lent, P.L.E.M. van; Barrera, P. |
| | 2001 | Resting naive T cells expressing ICAM-3 activate macrophages/dendritic cells in RA synovium mediated by design leading to elevated TNF alpha production: Identification of a new receptor involved in RA pathology | Lent, P.L.E.M. van; Torensma, R.; Sloetjes, A.; Barrera, P.; Figdor, C.G.; Berg, W.B. van den |
| | 1997 | Quantification of mRNA levels in joint capsule and articular cartilage of the murine knee joint by RT-PCR: Kinetics of stromelysin and IL-1 mRNA levels during arthritis. | Meurs, J.B.J. van; Lent, P.L.E.M. van; Joosten, L.A.B.; Kraan, P.M. van der; Berg, W.B. van den |
| | 1997 | Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice | Lent, P.L.E.M. van; Blom, A.B.; Holthuysen, A.E.M.; Jacobs, C.W.M.; Putte, L.B.A. van de; Berg, W.B. van den |
| | 1996 | Role of macrophages in chronic arthritis | Berg, W.B. van den; Lent, P.L.E.M. van |
| | 1996 | Phagocytic lining cells determine local expression of inflammation in type II collagen-induced arthritis | Lent, P.L.E.M. van; Holthuysen, A.E.M.; Bersselaar, L.A.M. van den; Rooijen, N. van; Joosten, L.A.B.; Loo, F.A.J. van de; Putte, L.B.A. van de; Berg, W.B. van den |
| | 1995 | Role of Interleukin 1 in antigen-induced exacerbations of murine arthritis | Loo, F.A.J. van de; Arntz, O.J.; Bakker, A.C.; Lent, P.L.E.M. van; Jacobs, H.J.M.; Berg, W.B. van den |
| | 1995 | Role of macrophage-like synovial lining cells in localization and expression of experimental arthritis | Lent, P.L.E.M. van; Holthuysen, A.E.M.; Bersselaar, L.A.M. van den; Rooijen, N. van; Putte, L.B.A. van de; Berg, W.B. van den |
| | 1995 | Role of Interleukin-1, Tumor Necrosis Factor alpha and Interleukin-6 in cartilage proteoglycan metabolism and destruction: effect of in situ blocking in murine antigen- and zymosan-induced arthritis | Loo, F.A.J. van de; Joosten, L.A.B.; Lent, P.L.E.M. van; Arntz, O.J.; Berg, W.B. van den |
| | 1995 | Major role for Interleukin 1 but not for tumor necrosis factor in early cartilage damage in immune complex arthritis in mice | Lent, P.L.E.M. van; Loo, F.A.J. van de; Holthuysen, A.E.M.; Bersselaar, L.A.M. van den; Vermeer, H.; Berg, W.B. van den |
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