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Full TextIssue DateTitleAuthor(s)
2012Catabolic Factors and Osteoarthritis-Conditioned Medium Inhibit Chondrogenesis of Human Mesenchymal Stem CellsHeldens, Genoveva; Davidson, E.N.; Vitters, E.L.; Schreurs, B.W.; Piek, E.; Berg, W.B. van den; Kraan, P.M. van der
2012Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis.Flogel, U.; Burghoff, S.; Lent, P.L.E.M. van; Temme, S.; Galbarz, L.; Ding, Z.; El-Tayeb, A.; Huels, S.; Bonner, F.; Borg, N. van den; Jacoby, C.; Muller, C.E.; Berg, W.B. van den; Schrader, J.
2012Comparison of three types of treatment modalities on the outcome of fingertip injuries.Berg, W.B. van den; Vergeer, R.A.; Sluis, C.K. van der; Duis, H.J. Ten; Werker, P.M.
2012Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?Kraan, P.M. van der; Berg, W.B. van den
2012Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 miceBombardieri, M.; Barone, F.; Lucchesi, D.; Nayar, S.; van den Berg, W.B.; Proctor, G.; Buckley, C.D.; Pitzalis, C.
2012Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation.Wenink, M.H.; Santegoets, K.C.M.; Platt, A.M.; Berg, W.B. van den; Riel, P.L.C.M. van; Garside, P.; Radstake, T.R.D.J.; McInnes, I.B.
2012Interleukin-32: A predominantly intracellular proinflammatory mediator that controls cell activation and cell deathHeinhuis, B.; Netea, M.G.; van den Berg, W.B.; Dinarello, C.A.; Joosten, L.A.B.
2012T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization.Koenders, M.I.; Marijnissen, R.J.; Joosten, L.A.B.; Abdollahi-Roodsaz, S.; Padova, F.E. Di; Loo, F.A.J. van de; Dulos, J.; Berg, W.B. van den; Boots, A.M.H.
2012Disease-dependent local IL-10 production ameliorates collagen induced arthritis in miceHenningsson, L.; Eneljung, T.; Jirholt, P.; Tengvall, S.; Lidberg, U.; van den Berg, W.B.; van de Loo, F.A.; Gjertsson, I.
2012Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells.Heldens, G.T.H.; Blaney Davidson, E.N.; Vitters, E.L.; Schreurs, B.W.; Piek, E.; Berg, W.B. van den; Kraan, P.M. van der
2012Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritisTer Huurne, M.; Schelbergen, R.; Blattes, R.; Blom, A.; de Munter, W.; Grevers, L.C.; Jeanson, J.; Noel, D.; Casteilla, L.; Jorgensen, C.; Berg, W.B. van den; van Lent, P.L.
2012Anti IL-17A therapy inhibits bone loss in TNF-alpha-mediated murine arthritis by modulation of the T-cell balance.Zwerina, K.; Koenders, M.I.; Hueber, A.; Marijnissen, R.J.; Baum, W.; Heiland, G.R.; Zaiss, M.; McLnnes, I.; Joosten, L.A.B.; Berg, W.B. van den; Zwerina, J.; Schett, G.
2012The loss of alpha2beta1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis.Peters, M.E.W.J.; Wendholt, D.; Strietholt, S.; Frank, S.; Pundt, N.; Korb-Pap, A.; Joosten, L.A.B.; Berg, W.B. van den; Kollias, G.; Eckes, B.; Pap, T.
2012Interleukin 32 (IL-32) contains a typical alpha-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.Heinhuis, B.; Koenders, M.I.; Berg, W.B. van den; Netea, M.G.; Dinarello, C.A.; Joosten, L.A.B.
2012Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4.Schelbergen, R.F.P.; Blom, A.B.; Bosch, M.H.J. van den; Sloetjes, A.W.; Abdollahi-Roodsaz, S.; Schreurs, B.W.; Mort, J.S.; Vogl, T.; Roth, J.; Berg, W.B. van den; Lent, P.L.E.M. van
2012Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis.Lent, P.L.E.M. van; Blom, A.B.; Schelbergen, R.F.P.; Sloetjes, A.W.; Lafeber, F.P.J.G.; Lems, W.F.; Cats, H.; Vogl, T.; Roth, J.; Berg, W.B. van den
2012Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice.Abdollahi-Roodsaz, S.; Loo, F.A.J. van de; Koenders, M.I.; Helsen, M.M.A.; Walgreen, B.; Bersselaar, L.A.M. van den; Arntz, O.J.; Takahashi, N.; Joosten, L.A.B.; Berg, W.B. van den
2012Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis.Marijnissen, R.J.; Koenders, M.I.; Veerdonk, F.L. van de; Dulos, J.; Netea, M.G.; Boots, A.M.H.; Joosten, L.A.B.; Berg, W.B. van den
2012Enhanced suppressor of cytokine signaling 3 in arthritic cartilage dysregulates human chondrocyte functionvan de Loo, F.A.; Veenbergen, S.; van den Brand, B.; Bennink, M.B.; Blaney-Davidson, E.; Arntz, O.J.; van Beuningen, H.M.; van der Kraan, P.M.; van den Berg, W.B.
2011Trapped in a vicious loop: Toll-like receptors sustain the spontaneous cytokine production by rheumatoid synoviumAbdollahi-Roodsaz, S.; Loo, F.A. van de; Berg, W.B. van den
2011Toll-like receptors in rheumatic diseases: Are we paying a high price for our defense against bugs?Santegoets, K.C.M.; Bon, L. van; Berg, W.B. van den; Wenink, M.H.; Radstake, T.R.D.J.
2011Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritisHofkens, W.; Grevers, L.C.; Walgreen, B.; Vries, T.J. de; Leenen, P.J.M.; Everts, V.; Storm, G.; Berg, W.B. van den; Lent, P.L. van
2011Osteoarthritis year 2010 in review: pathomechanismsvan den Berg, W.B.
2011Liposomal targeting of glucocorticoids to the inflamed synovium inhibits cartilage matrix destruction during murine antigen-induced arthritisHofkens, W.; Storm, G.; van den Berg, W.B.; van Lent, P.L.
2011Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint diseaseMaicas Blasco, N.; Ferrandiz, M.L.; Brines, R.; Ibanez, L.; Cuadrado, A.; Koenders, M.I.; Berg, W.B. van den; Alcaraz, M.J.
2011Up-Regulation of the Inflammatory Response by Ovariectomy in Collagen-Induced Arthritis. Effects of Tin Protoporphyrin IX.Ibanez, L.; Alcaraz, M.J.; Maicas Blasco, N.; Guede, D.; Caeiro, J.R.; Koenders, M.I.; Berg, W.B. van den; Ferrandiz, M.L.
2011Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in miceBluml, S.; Bonelli, M.; Niederreiter, B.; Puchner, A.; Mayr, G.; Hayer, S.; Koenders, M.I.; Berg, W.B. van den; Smolen, J.; Redlich, K.
2011S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll-like receptor 4: implications for bone destruction in murine antigen-induced arthritisGrevers, L.C.; Vries, T.J. de; Vogl, T.; Abdollahi-Roodsaz, S.; Sloetjes, A.W.; Leenen, P.J.M.; Roth, J.; Everts, V.; van den Berg, W.B.; van Lent, P.L.
2011Toll-like receptor 4 signalling is specifically TGF-beta-activated kinase 1 independent in synovial fibroblastsGeurts, J.; van den Brand, B.T.; Wolf, A.; Abdollahi-Roodsaz, S.; Arntz, O.J.; Kracht, M.; van den Berg, W.B.; van de Loo, F.A.
2011Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcificationHellingman, C.A.; Davidson, E.N.; Koevoet, W.; Vitters, E.L.; Berg, W.B. van den; Osch, G.J. van; Kraan, P.M. van der
2011Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritisWenink, M.H.; Santegoets, K.C.M.; Butcher, J.; Bon, L. van; Lamers-Karnebeek, F.B.G.; Berg, W.B. van den; Riel, P.L. van; McInnes, I.B.; Radstake, T.R.D.J.
2011A pivotal role for antigen-presenting cells overexpressing SOCS3 in controlling invariant NKT cell responses during collagen-induced arthritisVeenbergen, S.; Bennink, M.B.; Affandi, A.J.; Bessis, N.; Biton, J.; Arntz, O.J.; Berg, W.B. van den; Loo, F.A. van de
2011A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblastsGeurts, J.; Vermeij, E.A.; Pohlers, D.; Arntz, O.J.; Kinne, R.W.; Berg, W.B. van den; Loo, F.A. van de
2011Animal models for arthritis: innovative tools for prevention and treatment.Kollias, G.; Papadaki, P.; Apparailly, F.; Vervoordeldonk, M.J.; Holmdahl, R.; Baumans, V.; Desaintes, C.; Santo, J. Di; Distler, J.; Garside, P.; Hegen, M.; Huizinga, T.W.J.; Jungel, A.; Klareskog, L.; McInnes, I.; Ragoussis, I.; Schett, G.; Hart, B.; Tak, P.P.; Toes, R.; Berg, W.B. van den; Wurst, W.; Gay, S.
2011Cytosolic phospholipase A2alpha gene silencing in the myeloid lineage alters development of Th1 responses and reduces disease severity in collagen-induced arthritisCourties, G.; Baron, M.; Presumey, J.; Escriou, V.; Lent, P.L.E.M. van; Scherman, D.; Cantagrel, A.; Berg, W.B. van den; Jorgensen, C.; Apparailly, F.; Davignon, J.L.
2011Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritisHeinhuis, B.; Koenders, M.M.J.F.; Loo, F.A.J. van de; Netea, M.G.; Berg, W.B. van den; Joosten, L.A.B.
2011Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascadeHeinhuis, B.; Koenders, M.M.J.F.; Riel, P.L.C.M. van; Loo, F.A.J. van de; Dinarello, C.A.; Netea, M.G.; Berg, W.B. van den; Joosten, L.A.B.
2011Safety of glucocorticoids can be improved by lower yet still effective dosages of liposomal steroid formulations in murine antigen-induced arthritis: comparison of prednisolone with budesonideHofkens, W.; Hoven, J.M. van den; Pesman, G.J.; Nabbe, K.C.A.M.; Sweep, F.C.; Storm, G.; Berg, W.B. van den; Lent, P.L. van
2011Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradationMarijnissen, R.J.; Koenders, M.M.J.F.; Smeets, R.L.; Stappers, M.H.T.; Nickerson-Nutter, C.; Joosten, L.A.B.; Boots, A.M.H.; Berg, W.B. van den
2011Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1beta, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritisKoenders, M.I.; Marijnissen, R.J.; Devesa, I.; Lubberts, E.; Joosten, L.A.B.; Roth, J.; Lent, P.L.E.M. van; Loo, F.A.J. van de; Berg, W.B. van den
2011The anti-CD20 antibody rituximab reduces the Th17 cell responseVeerdonk, F.L. van de; Lauwerys, B.; Marijnissen, R.J.; Timmermans, K.; Padova, F.E. Di; Koenders, M.M.J.F.; Gutierrez-Roelens, I.; Durez, P.; Netea, M.G.; Meer, J.W. van der; Berg, W.B. van den; Joosten, L.A.B.
2010Antigen-presenting cells and their Fcy and Toll-like receptors : leading suspects in autoimmunitySantegoets, Kim; Bon, L. van; Wenink, M.H.; Berg, W.B. van den
2010The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis.Bondeson, J.; Blom, A.B.; Wainwright, S.; Hughes, C.; Caterson, B.; Berg, W.B. van den
2010Recommendations for the use of preclinical models in the study and treatment of osteoarthritisPoole, R.; Blake, S.; Buschmann, M.; Goldring, S.; Laverty, S.; Lockwood, S.; Matyas, J.; McDougall, J.; Pritzker, K.; Rudolphi, K.; Berg, W.B. van den; Yaksh, T.
2010Translational mini-review series on Th17 cells: are T helper 17 cells really pathogenic in autoimmunity?Koenders, M.I.; Berg, W.B. van den
2010The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse.Glasson, S.S.; Chambers, M.G.; Berg, W.B. van den; Little, C.B.
2010Bone morphogenetic proteins and articular cartilage: To serve and protect or a wolf in sheep clothing's?Kraan, P.M. van der; Davidson, E.N.; Berg, W.B. van den
2010To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy.Blom, A.B.; Lent, P.L.E.M. van; Kraan, P.M. van der; Berg, W.B. van den
2010A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis.Kraan, P.M. van der; Blaney Davidson, E.N.; Berg, W.B. van den
2010IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2.Heinhuis, B.; Koenders, M.M.J.F.; Loo, F.A.J. van de; Lent, P.L.E.M. van; Kim, S.H.; Dinarello, C.A.; Joosten, L.A.B.; Berg, W.B. van den

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