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| Title: | Experiences with cerebrospinal fluid analysis in Dutch memory clinics |
| Author(s): | Spies, P.E. (321510186)
Slats, D. (321509501)
Ramakers, I.
Verhey, F.R.J. (087843706)
Olde Rikkert, M.G.M. (167212737) |
| Publication year: | 2011 |
| Document type: | Article / Letter to editor |
| Journal: | European Journal of Neurology |
| ISSN: | 1351-5101 |
| Volume: | vol. 18 |
| Issue: | iss. 7 |
| Start page: | p. 1014 |
| End page: | p. 1016 |
| Annotation: | Spies, P E Slats, D Ramakers, I Verhey, F R J Olde Rikkert, M G M Research Support, Non-U.S. Gov't England Eur J Neurol. 2011 Jul;18(7):1014-6. doi: 10.1111/j.1468-1331.2010.03222.x. Epub 2010 Sep 16. |
| Abstract: | BACKGROUND: Evidence on cerebrospinal fluid (CSF) analysis to demonstrate Alzheimer's disease has not yet been implemented in diagnostic guidelines. METHODS: We investigated the use of CSF analysis in a survey amongst all known memory clinics in the Netherlands, of which 85 of 113 (75.2%) responded. RESULTS: Sixty per cent of respondents used CSF analysis in 5% (median) of patients. The analysis almost always confirmed the working diagnosis in 68.4% and sometimes changed it in 28.2%. Complications occurred very infrequently (0%, median) and were mild. Reasons not to perform CSF analysis included the lack of clear recommendations in diagnostic guidelines. CONCLUSIONS: These results ask for a guideline update to clarify the use of CSF analysis as an add-on diagnostic method. |
| Subject: | DCN 1: Perception and Action
NCEBP 11: Alzheimer Centre |
| Organization: | Geriatrics
UMCN Extern
IQ Healthcare |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/97899
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