Candida albicans morphogenesis and host defence: discriminating invasion from colonization.

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Title:	Candida albicans morphogenesis and host defence: discriminating invasion from colonization.
Author(s):	Gow, N.A. Veerdonk, F.L. van de (314336400) Brown, A.J. Netea, M.G. (171035860)
Publication year:	2011
Document type:	Article / Letter to editor
Journal:	Nature Reviews Microbiology
ISSN:	1740-1526
Volume:	vol. 10
Issue:	iss. 2
Start page:	p. 112
End page:	p. 122
Abstract:	Candida albicans is a common fungal pathogen of humans that colonizes the skin and mucosal surfaces of most healthy individuals. Until recently, little was known about the mechanisms by which mucosal antifungal defences tolerate colonizing C. albicans but react strongly when hyphae of the same microorganism attempt to invade tissue. In this Review, we describe the properties of yeast cells and hyphae that are relevant to their interaction with the host, and the immunological mechanisms that differentially recognize colonizing versus invading C. albicans.
Subject:	N4i 2: Invasive mycoses and compromised host NCMLS 1A: Infection and autoimmunity
Organization:	UMCN Extern General Internal Medicine
Appears in Collections:	Academic bibliography

Please use this identifier to cite or link to this item: http://hdl.handle.net/2066/95699