Subject:
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Research Programm of Donders Centre for Neuroscience |
Organization:
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Donders Centre for Neuroscience |
Abstract:
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Determining the perfusion territory of a specific artery in the brain can provide important
information in the diagnosis of many cerebrovascular diseases.
While a variety of methods exist to measure and quantify cerebral perfusion in general, only few of
them present the ability to gather regional information on cerebral perfusion that can be assigned
to a particular artery. Among such methods arterial spin labeling techniques based on magnetic
resonance imaging currently represent the most promising approaches with respect to a selective
measurement of flow territories of individual arteries.
The work of this doctoral thesis aims to fill the gap between the diagnostic possibilities of existing
techniques for flow territory mapping and the diagnostic demands required for an accurate
diagnosis in various cerebrovascular diseases.
The studies presented attempt to contribute to a technical solution of this problem with the
emphasis on selective perfusion measurements of individual intracranial arteries, and at the same
time to ensure clinical applicability.
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