The economic impact of high-need psoriasis in daily clinical practice before and after the introduction of biologics.
Fulltext:
88933.pdf
Embargo:
until further notice
Size:
80.91Kb
Format:
PDF
Description:
Publisher’s version
Publication year
2010Source
British Journal of Dermatology, 162, 6, (2010), pp. 1324-9ISSN
Annotation
01 juni 2010
Publication type
Article / Letter to editor
Display more detailsDisplay less details
Organization
Dermatology
Intensive Care
Health Evidence
IQ Healthcare
Medical Psychology
Former Organization
Epidemiology, Biostatistics & HTA
Journal title
British Journal of Dermatology
Volume
vol. 162
Issue
iss. 6
Page start
p. 1324
Page end
p. 9
Subject
N4i 1: Pathogenesis and modulation of inflammation; NCEBP 8: Psychological determinants of chronic illnessAbstract
Background Although costs of biologics are high, effective treatment of patients with psoriasis may reduce the total health care costs, as it may limit the need for hospitalization. Objectives To investigate the economic impact of psoriasis, including direct costs, before and after the introduction of biologics, with special focus on hospitalized patients, treatment effectiveness and patient satisfaction with medication. Patients and methods A descriptive retrospective cohort study including 67 patients with high-need psoriasis was done. Direct costs were investigated for the biologic and pre-biologic period. Direct costs for a subgroup of hospitalized patients were analysed separately. Patient satisfaction with biologic treatment was measured using the Treatment Satisfaction Questionnaire for Medication (TSQM) version II. Effectiveness of biologic therapy was investigated by means of the Psoriasis Area and Severity Index (PASI). Results Mean total direct costs were euro10 146 per patient per year (PPPY) in the pre-biologic treatment period, compared with euro17 712 PPPY in the biologic treatment period. For six patients in the cohort, introduction of biologics led to a reduction of direct costs, as these patients did not need long hospitalizations. Treatment with biologics led to a decrease in PASI from 19.0 at the start of biologic therapy to 6.4 at analysis (66.4%). Patient satisfaction with biologics was high, indicated by a mean TSQM score of 77.8. Conclusions Introduction of biologic therapies may have cost-neutral or cost-saving effects for patients who otherwise require long hospitalization periods. Treatment with biologics proved effective and was accompanied by high satisfaction for the patients.
This item appears in the following Collection(s)
- Academic publications [238430]
- Electronic publications [122512]
- Faculty of Medical Sciences [90359]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.