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| Title: | Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tuberculous meningitis. |
| Author(s): | Alffenaar, J.W.C.
Altena, R. van
Bokkerink, H.J.
Luijckx, G.J.R.
Soolingen, D. van (148544304)
Aarnoutse, R.E. (256301077)
Werf, T.S. van der |
| Publication year: | 2009 |
| Document type: | Article / Letter to editor |
| Journal: | Clinical Infectious Diseases |
| ISSN: | 1058-4838 |
| Volume: | vol. 49 |
| Issue: | iss. 7 |
| Start page: | p. 1080 |
| End page: | p. 1082 |
| Abstract: | Moxifloxacin cerebrospinal fluid (CSF) penetration was evaluated by obtaining full plasma and CSF time concentration curves for 4 patients with tuberculous meningitis. The geometric mean ratio of the areas under the curve for CSF to plasma were 0.82 (range, 0.70-0.94) at 400 mg once per day and 0.71 (0.58-0.84) at 800 mg once per day. |
| Subject: | N4i 3: Poverty-related infectious diseases
NCEBP 13: Infectious diseases and international health |
| Organization: | UMCN Extern
Clinical Pharmacy |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/79494
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