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| Title: | Two newly identified genetic determinants of pigmentation in Europeans. |
| Author(s): | Sulem, P.
Gudbjartsson, D.F.
Stacey, S.N.
Helgason, A.
Rafnar, T.
Jakobsdottir, M.
Steinberg, S.
Gudjonsson, S.A.
Palsson, A.
Thorleifsson, G.
Palsson, S.
Sigurgeirsson, B.
Thorisdottir, K.
Ragnarsson, R.
Benediktsdottir, K.R.
Aben, K.K.H. (217174302)
Vermeulen, H.H.M. (298981033)
Goldstein, A.M.
Tucker, M.A.
Kiemeney, L.A.L.M. (105132063)
Olafsson, J.H.
Gulcher, J.
Kong, A.
Thorsteinsdottir, U.
Stefansson, K. |
| Publication year: | 2008 |
| Document type: | Article / Letter to editor |
| Journal: | Nature Genetics |
| ISSN: | 1061-4036 |
| Volume: | vol. 40 |
| Issue: | iss. 7 |
| Start page: | p. 835 |
| End page: | p. 837 |
| Abstract: | We present results from a genome-wide association study for variants associated with human pigmentation characteristics among 5,130 Icelanders, with follow-up analyses in 2,116 Icelanders and 1,214 Dutch individuals. Two coding variants in TPCN2 are associated with hair color, and a variant at the ASIP locus shows strong association with skin sensitivity to sun, freckling and red hair, phenotypic characteristics similar to those affected by well-known mutations in MC1R. |
| Subject: | EBP 1: Determinants in Health and Disease
EBP 2: Effective Hospital Care
UMCN 1.2: Molecular diagnosis, prognosis and monitoring |
| Organization: | Epidemiology, Biostatistics & HTA
UMCN Extern
Urology |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/70561
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