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| Title: | Dendritic cell vaccination and immune monitoring. |
| Author(s): | Aarntzen, E.H.J.G. (314664688)
Figdor, C.G. (067631614)
Adema, G.J. (087131714)
Punt, C.J.A. (085052248)
Vries, I.J.M. de (162370016) |
| Publication year: | 2008 |
| Document type: | Article / Letter to editor |
| Journal: | Cancer Immunology Immunotherapy |
| ISSN: | 0340-7004 |
| Volume: | vol. 57 |
| Issue: | iss. 10 |
| Start page: | p. 1559 |
| End page: | p. 1568 |
| Abstract: | We exploited dendritic cells (DC) to vaccinate melanoma patients. We recently demonstrated a statistical significant correlation between favorable clinical outcome and the presence of vaccine-related tumor antigen-specific T cells in delayed type hypersensitivity (DTH) skin biopsies. However, favorable clinical outcome is only observed in a minority of the treated patients. Therefore, it is obvious that current DC-based protocols need to be improved. For this reason, we study in small proof of principle trials the fate, interactions and effectiveness of the injected DC. |
| Subject: | NCMLS 1: Immunity, infection and tissue repair
UMCN 1.4: Immunotherapy, gene therapy and transplantation |
| Organization: | Medical Oncology
Tumorimmunology |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/69708
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