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| Title: | Male-pattern baldness susceptibility locus at 20p11. |
| Author(s): | Richards, J.B.
Yuan, X.
Geller, F.
Waterworth, D.
Bataille, V.
Glass, D.
Song, K.
Waeber, G.
Vollenweider, P.
Aben, K.K.H. (217174302)
Kiemeney, L.A.L.M. (105132063)
Walters, B.
Soranzo, N.
Thorsteinsdottir, U.
Kong, A.
Rafnar, T.
Deloukas, P.
Sulem, P.
Stefansson, H.
Stefansson, K.
Spector, T.D.
Mooser, V. |
| Publication year: | 2008 |
| Document type: | Article / Letter to editor |
| Journal: | Nature Genetics |
| ISSN: | 1061-4036 |
| Volume: | vol. 40 |
| Issue: | iss. 11 |
| Start page: | p. 1282 |
| End page: | p. 1284 |
| Abstract: | We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)). |
| Subject: | UMCN 1.2: Molecular diagnosis, prognosis and monitoring |
| Organization: | Urology
UMCN Extern
Epidemiology, Biostatistics & HTA |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/69120
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