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| Title: | Safety and efficacy of a NRTI-sparing HAART regimen of efavirenz and lopinavir/ritonavir in HIV-1-infected children. |
| Author(s): | Fraaij, P.L.
Neubert, J.
Bergshoeff, A.S. (263438953)
Rossum, A.M. van
Hartwig, N.G.
Schroten, H.
Korn, K.
Burger, D.M. (119962306)
Groot, R. de (073314110)
Niehues, T. |
| Publication year: | 2004 |
| Document type: | Article / Letter to editor |
| Journal: | Antiviral Therapy |
| ISSN: | 1359-6535 |
| Volume: | vol. 9 |
| Issue: | iss. 2 |
| Start page: | p. 297 |
| End page: | p. 299 |
| Abstract: | We studied a nucleoside reverse transcriptase inhibitor (NRTI)-sparing regimen for the treatment of children infected with NRTI-resistant HIV-1. The combination of lopinavir/ritonavir and efavirenz suppressed HIV-1 levels for a prolonged period and resulted in a significant increase in CD4+ T cell numbers despite an extensive prior treatment with NRTI (>4 years). Observed side effects were transient with the exception of dyslipidaemia. |
| Subject: | UMCN 4.1: Microbial pathogenesis and host defense |
| Organization: | UMCN Extern
Clinical Pharmacy
Paediatrics |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/59321
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