A set of BAC clones spanning the human genome.

Title:	A set of BAC clones spanning the human genome.
Author(s):	Krzywinski, M. Bosdet, I. Smailus, D. Chiu, R. Mathewson, C. Wye, N. Barber, S. Brown-John, M. Chan, S. Chand, S. Cloutier, A. Girn, N. Lee, D. Masson, A. Mayo, M. Olson, T. Pandoh, P. Prabhu, A.L. Schoenmakers, E.F.P.M. (298977346) Tsai, M.Y. Albertson, D. Lam, W.W. Choy, C.O. Osoegawa, K. Zhao, S. Jong, P.J. de Schein, J. Jones, S. Marra, M.A.
Publication year:	2004
Document type:	Article / Letter to editor
Journal:	Nucleic Acids Research
ISSN:	0305-1048
Volume:	vol. 32
Issue:	iss. 12
Start page:	p. 3651
End page:	p. 3660
Abstract:	Using the human bacterial artificial chromosome (BAC) fingerprint-based physical map, genome sequence assembly and BAC end sequences, we have generated a fingerprint-validated set of 32 855 BAC clones spanning the human genome. The clone set provides coverage for at least 98% of the human fingerprint map, 99% of the current assembled sequence and has an effective resolving power of 79 kb. We have made the clone set publicly available, anticipating that it will generally facilitate FISH or array-CGH-based identification and characterization of chromosomal alterations relevant to disease.
Subject:	UMCN 1.2: Molecular diagnosis, prognosis and monitoring
Organization:	UMCN Extern Human Genetics
Appears in Collections:	Academic bibliography

Please use this identifier to cite or link to this item: http://hdl.handle.net/2066/57492