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Title: Sympathetic nervous system function in HIV-associated adipose redistribution syndrome.
Author(s): Gurp, P.J.M. van (298977494)
Tack, C.J.J. (155613936)
Valk, M. van der
Reiss, P.
Lenders, J.W.M. (073474959)
Sweep, C.G.J. (074620967)
Sauerwein, H.P.
Publication year: 2006
Document type: Article / Letter to editor
Journal: AIDS
ISSN: 0269-9370
Volume: vol. 20
Issue: iss. 5
Start page: p. 773
End page: p. 775
Abstract: It was recently suggested that HIV-associated adipose redistribution syndrome (HARS) results from an autonomic dysbalance. We investigated the local and global sympathetic nervous system function of patients with HIV-1 infection and HARS. Interstitial noradrenaline concentrations in skeletal muscle and subcutaneous adipose tissue were increased in the absence of changes in global sympathetic nerve activity, consistent with locally increased sympathetic activity. This could promote localized lipolysis in subcutaneous adipose tissue and contribute to the development of HARS.
Subject: UMCN 2.2: Vascular medicine and diabetes
UMCN 5.2: Endocrinology and reproduction
Organization: General Internal Medicine
UMCN Extern
Chemical Endocrinology
Appears in Collections:Academic bibliography

Please use this identifier to cite or link to this item: http://hdl.handle.net/2066/51401

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