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| Title: | Methylsulfonylmethane (MSM) Ingestion Causes a Significant Resonance in Proton Magnetic Resonance Spectra of Brain and Cerebrospinal Fluid. |
| Author(s): | Willemsen, M.A.A.P. (23476452X)
Engelke, U.F.H. (298974649)
Graaf, M. van der (096424346)
Wevers, R.A. (068311508) |
| Publication year: | 2006 |
| Document type: | Article / Letter to editor |
| Journal: | Neuropediatrics |
| ISSN: | 0174-304X |
| Volume: | vol. 37 |
| Issue: | iss. 5 |
| Start page: | p. 312 |
| End page: | p. 314 |
| Abstract: | The use of methylsulfonylmethane (MSM), available as an "over-the-counter" dietary supplement, led to the occurrence of an abnormal resonance at 3.15 ppm in the IN VIVO brain proton MR spectrum as well as the in vitro cerebrospinal fluid NMR study of a 4-year-old girl. The concentration of this compound amounted to 1.2 mmol/l in brain tissue and 1.7 mmol/l in cerebrospinal fluid. Our findings illustrate that ingestion of exogenous compounds, e.g., in medication, food or "innocent" supplements, may lead to abnormal resonances in spectroscopy studies that might be difficult to assign. |
| Subject: | UMCN 3.2: Cognitive neurosciences |
| Organization: | Paediatrics
FSW_Fac. algemeen
Neurology |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/50557
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