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| Title: | Nucleotide oligomerization domain 2 (Nod2) is not involved in the pattern recognition of Candida albicans. |
| Author(s): | Graaf, C.A.A. van der (297370715)
Netea, M.G. (171035860)
Franke, B. (182880869)
Girardin, S.E.
Meer, J.W.M. van der (070708525)
Kullberg, B.J. (074528858) |
| Publication year: | 2006 |
| Document type: | Article / Letter to editor |
| Journal: | Clinical and vaccine immunology |
| ISSN: | 1556-6811 |
| Volume: | vol. 13 |
| Issue: | iss. 3 |
| Start page: | p. 423 |
| End page: | p. 425 |
| Abstract: | Nucleotide-binding oligomerization domain 2 (Nod2) pathways are known to interact with Toll-like receptor 2 (TLR2) and TLR4, which are pattern recognition receptors for Candida albicans. We observed that the prevalence of Nod2 polymorphisms was not increased in patients with Candida infections. Candida-induced cytokine production in individuals with Nod2 polymorphisms was unaffected. We conclude that Nod2 is unlikely to play an important role in the recognition of Candida albicans. |
| Subject: | EBP 3: Effective Primary Care and Public Health
UMCN 4.1: Microbial pathogenesis and host defense
UMCN 5.1: Genetic defects of metabolism |
| Organization: | General Internal Medicine
Psychiatry
UMCN Extern |
| Appears in Collections: | Academic bibliography
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2066/49534
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