Publication year
2003Source
Physiological Measurement, 24, 4, (2003), pp. N35-40ISSN
Publication type
Article / Letter to editor
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Organization
Paediatrics - OUD tm 2017
Journal title
Physiological Measurement
Volume
vol. 24
Issue
iss. 4
Page start
p. N35
Page end
p. 40
Subject
UMCN 2.1: Heart, lung and circulation; UMCN 3.1: Neuromuscular development and genetic disordersAbstract
This paper describes the simultaneous use of two, noninvasive, near-infrared techniques near-infrared spectroscopy (NIRS) and a continuous wave NIR laser Doppler flow system (LDF) to measure changes in the blood oxygenation, blood concentration and blood flow velocity in the brain. A piglet was used as animal model. A controlled change in the arterial CO2 pressure (PaCO2) was applied for achieving changes in the listed cerebrovascular parameters. The time courses of blood concentration parameters (NIRS) and RMS blood flow velocity (LDF) were found to correspond closely with those of carotid blood flow and arterial carbon dioxide pressure (PaCO2). This result shows the additional value of LDF when combined with NIRS, preferably in one instrument. Development of pulsed LDF for regional blood flow measurement is indicated.
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- Academic publications [238441]
- Faculty of Medical Sciences [90373]
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