Emotion perception and executive control interact in the salience network during emotionally charged working memory processing
Publication year
2014Source
Human Brain Mapping, 35, 11, (2014), pp. 5606-16ISSN
Publication type
Article / Letter to editor
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Organization
Donders Centre for Cognitive Neuroimaging
Cognitive Neuroscience
PI Group Affective Neuroscience
Journal title
Human Brain Mapping
Volume
vol. 35
Issue
iss. 11
Page start
p. 5606
Page end
p. 16
Subject
130 000 Cognitive Neurology & Memory; Radboudumc 12: Sensory disorders DCMN: Donders Center for Medical Neuroscience; Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical NeuroscienceAbstract
Processing of emotional stimuli can either hinder or facilitate ongoing working memory (WM); however, the neural basis of these effects remains largely unknown. Here we examined the neural mechanisms of these paradoxical effects by implementing a novel emotional WM task in an fMRI study. Twenty-five young healthy participants performed an N-back task with fearful and neutral faces as stimuli. Participants made more errors when performing 0-back task with fearful versus neutral faces, whereas they made fewer errors when performing 2-back task with fearful versus neutral faces. These emotional impairment and enhancement on behavioral performance paralleled significant interactions in distributed regions in the salience network including anterior insula (AI) and dorsal cingulate cortex (dACC), as well as in emotion perception network including amygdala and temporal-occipital association cortex (TOC). The dorsal AI (dAI) and dACC were more activated when comparing fearful with neutral faces in 0-back task. Contrarily, dAI showed reduced activation, while TOC and amygdala showed stronger responses to fearful as compared to neutral faces in the 2-back task. These findings provide direct neural evidence to the emerging dual competition model suggesting that the salience network plays a critical role in mediating interaction between emotion perception and executive control when facing ever-changing behavioral demands.
This item appears in the following Collection(s)
- Academic publications [238430]
- Donders Centre for Cognitive Neuroimaging [3824]
- Electronic publications [122512]
- Faculty of Medical Sciences [90359]
- Open Access publications [97507]
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