Publication year
2014Source
Advances in Experimental Medicine and Biology, 813, (2014), pp. 81-91ISSN
Publication type
Article / Letter to editor
Display more detailsDisplay less details
Organization
SW OZ DCC SMN
Journal title
Advances in Experimental Medicine and Biology
Volume
vol. 813
Page start
p. 81
Page end
p. 91
Subject
Biological psychology; DI-BCB_DCC_Theme 3: Plasticity and Memory; Biologische psychologieAbstract
The distinction between generalized and partial epilepsies is probably one, if not the most, pregnant assertions in modern epileptology. Both absence and generalized tonic-clonic seizures, the prototypic seizures found in generalized epilepsies, are classically seen as the result of a rapid, synchronous recruitment of neuronal networks resulting in impairment of consciousness and/or convulsive semiology. The term generalized also refers to electroencephalographic presentation, with bilateral, synchronous activity, such as the classical 3 Hz spike and wave discharges of typical absence epilepsy. However, findings obtained from electrophysiological and functional imaging studies over the last few years, contradict this view, showing a rather focal onset for most of the so-called generalized seizure types. Therefore, we ask here the question whether “generalized epilepsy” does indeed exist.
This item appears in the following Collection(s)
- Academic publications [238430]
- Faculty of Social Sciences [29483]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.