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Browsing by Author Kolkman, A.J.

Full Text	Issue Date	Title	Author(s)
	2012	NRM spectroscopy in drug discovery : application and development of NMR based methodologies for P450BM3 drug metabolism, metabolite identification and mixture analysis	Kolkman, A.J.
	2012	Regioselective 16-b hydoxylation of steroids by rational redesign of the active site of cytochrome p450 bm3	Rea, V.; Kolkman, A.J.; Vottero, E.; Stronks, E.J.; Vermeulen, N.P.E., et al
	2011	Active site substitution a82w improves the regioselectivity of steroid hydroxylation by cytochrome p450 bm3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies	Rea, V.; Kolkman, A.J.; Vottero, E.; Stronks, E.J.; Ampt, K.A., et al
	2011	Liquid state nmr spectroscopy as a tool to obtain structural and binding information of drug molecules metabolized by p450bm3 enzymes	Kolkman, A.J.; Draaisma, V.R.J.; Tessari, M.; Vottero, E.V.; Ampt, K.A.M., et al
	2010	Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR	Vlieger, J.S.B. de; Kolkman, A.J.; Ampt, K.A.M.; Commandeur, J.N.M.; Vermeulen, N.P.E., et al
	2010	Cytochrome P450 BM3 Mutants as NOVEL Biocatalytic TOOLS for Regioselective Hydroxylation of Steroids	Rea, V.; Kolkman, A.J.; Vottero, E.; Honing, M.; Wijmenga, S.S., et al
	2009	A Microfluidic High-Resolution NMR Flow Probe	Bart, J.; Kolkman, A.J.; Oosthoek-de Vries, A.J.; Koch, K.; Nieuwland, P.J., et al